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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU00990


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00990
General rule information [?]

Accession PRU00990
Dates 13-NOV-2014 (Created)
19-NOV-2022 (Last updated, Version 7)
Data class Domain;
Predictors PROSITE; PS51657; PSRV_HELICASE
Name (+)RNA virus helicase core domain
Function The helicase core contains two structural domains, an N-terminal ATP-binding domain and a C-terminal domain.
Scope(s) Viruses
Riboviria
Example(s) P0C6Y1;

Propagated annotation [?]

Keywords [?]

ATP-binding
Helicase
Hydrolase
Nucleotide-binding

Gene Ontology [?]

GO:0004386; Molecular function:helicase activity
GO:0005524; Molecular function:ATP binding
GO:0016787; Molecular function:hydrolase activity
GO:0000166; Molecular function:nucleotide binding

Features [?]

From: PS51657
Key From To Description Tag Condition FTGroup
DOMAIN from 155 /note="(+)RNA virus helicase ATP-binding #"
BINDING 33 40 /ligand="a ribonucleoside 5'-triphosphate"
/ligand_id="ChEBI:CHEBI:61557"
DOMAIN 156 to /note="(+)RNA virus helicase C-terminal #"

Additional information [?]

Size range 206-377 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]