ProRule PRU01002
General rule information
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| PURL | https://purl.expasy.org/prosite/rule/PRU01002 |
| Accession | PRU01002 |
| Dates | 28-MAY-2013 (Created)
22-NOV-2019 (Last updated, Version 5) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51667; WRC |
Name | WRC domain |
| Function | The WRC domain contains two distinctive features, namely a putative nuclear localization signal and a zinc-finger motif consisting of the conserved spacing of three Cys and one His residues (C3H motif). It has been suggested that the WRC domain functions in DNA binding. |
| Scope(s) |
Eukaryota Magnoliopsida |
| Example(s) | O81001 (GRF1_ARATH); |
Propagated annotation
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Comments
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| case <FTGroup:1> | |
| SUBCELLULAR LOCATION | Nucleus. |
| end case | |
Keywords
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| Nucleus | |
| end case | |
Gene Ontology
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| case <FTGroup:1> | |
| GO:0005634; Cellular component:nucleus | |
Features
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| From: PS51667 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="WRC #" | |||||||||
| MOTIF | 6 | 16 | /note="Bipartite nuclear localization signal" | R-C-[KR]-R-T-D-G-K-K-W-R | 1 | |||||||
| MOTIF | 34 | 41 | /note="Bipartite nuclear localization signal" | [KR]-[GNS]-[KR]-[GHKNP]-R-[AS]-R-K | 1 | |||||||
Additional information
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| Size range | 35-55 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1-2 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [26] All [ 26 ]
- Retrieve set of proteins with 3D structure for this domain