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| annotation rule: PRU01002 |
General rule information
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| Accession | PRU01002 |
| Dates | 28-MAY-2013 (Created) 22-NOV-2019 (Last updated, Version 5) |
| Data class | Domain |
| Predictors | PROSITE; PS51667; WRC |
| Name | WRC domain |
| Function | The WRC domain contains two distinctive features, namely a putative nuclear localization signal and a zinc-finger motif consisting of the conserved spacing of three Cys and one His residues (C3H motif). It has been suggested that the WRC domain functions in DNA binding. |
Propagated annotation
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Comments
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case <FTGroup:1>
| Subcellular location | Nucleus. |
end case
Gene Ontology
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case <FTGroup:1>
GO:0005634; Cellular component: nucleus.
Keywords
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end case
Features
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| From: PS51667 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | WRC # | |||||||||
| MOTIF | 6 | 16 | Bipartite nuclear localization signal | R-C-[KR]-R-T-D-G-K-K-W-R | 1 | |||||||
| MOTIF | 34 | 41 | Bipartite nuclear localization signal | [KR]-[GNS]-[KR]-[GHKNP]-R-[AS]-R-K | 1 | |||||||
Additional information
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| Size range | 35-55 amino acids |
| Related rules | None |
| Repeats | 1-2 |
| Topology | Undefined |
| Example | O81001 (GRF1_ARATH) |
| Scope | Eukaryota; Magnoliopsida |
| Comments | None |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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