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General rule information [?]

Accession PRU01002
Dates 28-MAY-2013 (Created)
22-NOV-2019 (Last updated, Version 5)
Data class Domain
Predictors PROSITE; PS51667; WRC
Name WRC domain
Function The WRC domain contains two distinctive features, namely a putative nuclear localization signal and a zinc-finger motif consisting of the conserved spacing of three Cys and one His residues (C3H motif). It has been suggested that the WRC domain functions in DNA binding.

Propagated annotation [?]

Comments [?]

case <FTGroup:1>
Subcellular location Nucleus.
end case

Gene Ontology [?]

case <FTGroup:1>
GO:0005634; Cellular component: nucleus.

Keywords [?]

end case

Features [?]

From: PS51667
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       WRC #        
MOTIF     6     16       Bipartite nuclear localization signal     R-C-[KR]-R-T-D-G-K-K-W-R   1
MOTIF     34     41       Bipartite nuclear localization signal     [KR]-[GNS]-[KR]-[GHKNP]-R-[AS]-R-K   1

Additional information [?]

Size range 35-55 amino acids
Related rules None
Repeats 1-2
Topology Undefined
Example O81001 (GRF1_ARATH)
Eukaryota; Magnoliopsida
Comments None


PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]

UniProtKB/Swiss-Prot sets
Eukaryota [26]