ProRule PRU01005
General rule information
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| Accession | PRU01005 |
| Dates | 7-JUN-2013 (Created)
22-NOV-2019 (Last updated, Version 5) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51670; SHKT |
Name | ShKT domain |
| Function | In venomous creatures, the ShKT domain may have been modified to give rise to potent ion channel blockers, whereas the incorporation of this domain into plant oxidoreductases and prolyl hydroxylases and into worm astacin-like metalloproteases and trypsin-like serines protaeses produced enzymes with potential channel-modulatory activity. |
| Scope(s) |
Eukaryota Metazoa |
| Example(s) | P29187 (K1A_STIHL); |
Propagated annotation
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Keywords
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| case <FTTag:disulf> | |
| Disulfide bond | |
| end case | |
Features
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| From: PS51670 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="ShKT #" | |||||||||
| DISULFID | 1 | 35 | disulf | C-x*-C | ||||||||
| DISULFID | 10 | 28 | disulf | C-x*-C | ||||||||
| DISULFID | 19 | 32 | disulf | C-x*-C | ||||||||
Additional information
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| Size range | 0-49 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1-4 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [132] All [ 132 ]
- Retrieve set of proteins with 3D structure for this domain