ProRule PRU01005

General rule information [?]

Accession PRU01005
Dates 7-JUN-2013 (Created)
22-NOV-2019 (Last updated, Version 5)
Data class Domain;
Predictors PROSITE; PS51670; SHKT
Name ShKT domain
Function In venomous creatures, the ShKT domain may have been modified to give rise to potent ion channel blockers, whereas the incorporation of this domain into plant oxidoreductases and prolyl hydroxylases and into worm astacin-like metalloproteases and trypsin-like serines protaeses produced enzymes with potential channel-modulatory activity.
Scope(s) Eukaryota
Example(s) P29187 (K1A_STIHL);

Propagated annotation [?]

Keywords [?]

case <FTTag:disulf>
Disulfide bond
end case

Features [?]

From: PS51670
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="ShKT #"
DISULFID 1 35 disulf C-x*-C
DISULFID 10 28 disulf C-x*-C
DISULFID 19 32 disulf C-x*-C

Additional information [?]

Size range 0-49 amino acids
Related rules None
Fusion None
Repeats 1-4
Topology Undefined


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UniProtKB rule member sequences [?]