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annotation rule: PRU01005

General rule information [?]

Accession PRU01005
Dates 7-JUN-2013 (Created)
22-NOV-2019 (Last updated, Version 5)
Data class Domain
Predictors PROSITE; PS51670; SHKT
Name ShKT domain
Function In venomous creatures, the ShKT domain may have been modified to give rise to potent ion channel blockers, whereas the incorporation of this domain into plant oxidoreductases and prolyl hydroxylases and into worm astacin-like metalloproteases and trypsin-like serines protaeses produced enzymes with potential channel-modulatory activity.

Propagated annotation [?]

Keywords [?]

case <FTTag:disulf>
end case

Features [?]

From: PS51670
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       ShKT #        
DISULFID     1     35           disulf   C-x*-C  
DISULFID     10     28           disulf   C-x*-C  
DISULFID     19     32           disulf   C-x*-C  

Additional information [?]

Size range 0-49 amino acids
Related rules None
Repeats 1-4
Topology Undefined
Example P29187 (K1A_STIHL)
Eukaryota; Metazoa
Comments None


PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]