Home  |  Contact
annotation rule: PRU01027

General rule information [?]

Accession PRU01027
Dates 30-OCT-2013 (Created)
22-NOV-2019 (Last updated, Version 8)
Data class Domain
Predictors PROSITE; PS51690; ALPHAVIRUS_CP
Name Alphavirus core protein (CP) domain
Function The alphavirus CP forms peptidase family S3.

Propagated annotation [?]


Description [?]

case <FTGroup:1>
+ RecName: EC 3.4.21.90;

Comments [?]

Catalytic activity Reaction=Autocatalytic release of the core protein from the N-terminus of the togavirus structural polyprotein by hydrolysis of a -Trp-|-Ser- bond.; EC=3.4.21.90;
end case


Gene Ontology [?]

case <FTGroup:1>
GO:0004252; Molecular function: serine-type endopeptidase activity.
GO:0006508; Biological process: proteolysis.

Keywords [?]

Hydrolase
Protease
Serine protease
end case


Features [?]

From: PS51690
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       Peptidase S3 #        
ACT_SITE     27     27       Charge relay system     H   1
ACT_SITE     49     49       Charge relay system     D   1
ACT_SITE     101     101       Charge relay system     S   1

Additional information [?]

Size range 139-161 amino acids
Related rules None
Repeats 1
Topology Undefined
Example P22056 (POLS_ONNVG)
Scope
Viruses; Alphavirus
Comments None

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.


View rule in raw text format (no links)


UniProtKB rule member sequences [?]