ProRule PRU01027
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PURL: https://purl.expasy.org/prosite/rule/PRU01027
General rule information
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| Accession | PRU01027 |
| Dates | 30-OCT-2013 (Created)
22-NOV-2019 (Last updated, Version 9) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51690; ALPHAVIRUS_CP |
Name | Alphavirus core protein (CP) domain |
| Function | The alphavirus CP forms peptidase family S3. |
| Scope(s) |
Viruses Alphavirus |
| Example(s) | P22056 (POLS_ONNVG); |
Propagated annotation
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Identifier, protein and gene names
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| case <FTGroup:1> | |
| Protein name | + RecName: EC=3.4.21.90; |
Comments
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| CATALYTIC ACTIVITY | Reaction=Autocatalytic release of the core protein from the N-terminus of the togavirus structural polyprotein by hydrolysis of a -Trp-|- Ser- bond.; EC=3.4.21.90; |
| end case | |
Keywords
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| Hydrolase | |
| Protease | |
| Serine protease | |
| end case | |
Gene Ontology
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| case <FTGroup:1> | |
| GO:0004252; Molecular function:serine-type endopeptidase activity | |
| GO:0006508; Biological process:proteolysis | |
Features
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| From: PS51690 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="Peptidase S3 #" | |||||||||
| ACT_SITE | 27 | 27 | /note="Charge relay system" | H | 1 | |||||||
| ACT_SITE | 49 | 49 | /note="Charge relay system" | D | 1 | |||||||
| ACT_SITE | 101 | 101 | /note="Charge relay system" | S | 1 | |||||||
Additional information
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| Size range | 139-161 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
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UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Viruses [35] All [ 35 ]
- Retrieve set of proteins with 3D structure for this domain