General rule information
[?]
Accession |
PRU01031 |
Dates |
21-AUG-2014 (Created) 14-MAY-2022 (Last updated, Version 6) |
Predictors |
PROSITE; PS51694; PEPTIDASE_M66
|
Name |
Peptidase family M66 domain |
Function |
The peptidase family M66 domain is a zinc metalloprotease. |
Propagated annotation
[?]
case <FTGroup:1>
end case
case <FTGroup:2>
Cofactor |
Zn(2+) Note: Binds 1 zinc ion per subunit. |
end case
case <FTGroup:2>
GO:0046872; Molecular function: metal ion binding.
end case
case <FTGroup:1>
GO:0006508; Biological process: proteolysis.
GO:0004222; Molecular function: metalloendopeptidase activity.
end case
case <FTGroup:1>
end case
case <FTGroup:2>
end case
From: PS51694 |
Key
|
|
From
|
|
To
|
|
Description
|
|
Tag
|
|
Condition
|
|
FTGroup
|
DOMAIN
|
|
from
|
|
to
|
|
Peptidase M66
|
|
|
|
|
|
|
ACT_SITE
|
|
154
|
|
154
|
|
|
|
|
|
E
|
|
1
|
BINDING
|
|
153
|
|
153
|
|
/ligand="Zn(2+)" /ligand_id="29105" /ligand_note="catalytic
|
|
|
|
H
|
|
1,2
|
BINDING
|
|
157
|
|
157
|
|
/ligand="Zn(2+)" /ligand_id="29105" /ligand_note="catalytic
|
|
|
|
H
|
|
1,2
|
BINDING
|
|
163
|
|
163
|
|
/ligand="Zn(2+)" /ligand_id="29105" /ligand_note="catalytic
|
|
|
|
H
|
|
1,2
|
Additional information
[?]
Size range |
245-282 amino acids |
Related rules |
None |
Repeats |
1 |
Topology |
Undefined |
Example |
O82882 (STCE_ECO57) |
Scope |
Bacteria; Proteobacteria
Eukaryota; Dictyostelium |
Comments |
None |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and
distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives
(CC BY-NC-ND 4.0) License, see
prosite_license.html.
UniProtKB rule member sequences
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