ProRule PRU01037
General rule information
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| PURL | https://purl.expasy.org/prosite/rule/PRU01037 |
| Accession | PRU01037 |
| Dates | 22-AUG-2014 (Created)
22-NOV-2019 (Last updated, Version 4) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51700; SEPARIN |
Name | SEPARIN core domain |
| Function | The separin core domain contains a conserved histidine and cyteine residue, which are hallmarks of cysteine proteases. The separin core domain forms the peptidase C50 family. |
| Scope(s) |
Eukaryota |
| Example(s) | Q14674 (ESPL1_HUMAN); |
Propagated annotation
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Keywords
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| case <FTTag:protease> | |
| Hydrolase | |
| Protease | |
| Thiol protease | |
| end case | |
Features
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| From: PS51700 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="Peptidase C50 #" | |||||||||
| ACT_SITE | 85 | 85 | protease | C | ||||||||
Additional information
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| Size range | 85-110 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [7] All [ 7 ]
- Retrieve set of proteins with 3D structure for this domain