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annotation rule: PRU01037

General rule information [?]

Accession PRU01037
Dates 22-AUG-2014 (Created)
22-NOV-2019 (Last updated, Version 4)
Data class Domain
Predictors PROSITE; PS51700; SEPARIN
Name SEPARIN core domain
Function The separin core domain contains a conserved histidine and cyteine residue, which are hallmarks of cysteine proteases. The separin core domain forms the peptidase C50 family.

Propagated annotation [?]


Keywords [?]

case <FTTag:protease>
Hydrolase
Protease
Thiol protease
end case


Features [?]

From: PS51700
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       Peptidase C50 #        
ACT_SITE     85     85           protease   C  

Additional information [?]

Size range 85-110 amino acids
Related rules None
Repeats 1
Topology Undefined
Example Q14674 (ESPL1_HUMAN)
Scope
Eukaryota
Comments None

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.


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UniProtKB rule member sequences [?]