ProRule PRU01051

General rule information [?]

Accession PRU01051
Dates 20-MAY-2020 (Created)
-- (Last updated, Version 1)
Data class Domain;
Predictors PROSITE; PS51714; G_BMS1
Name Bms1-type guanine nucleotide-binding (G) domain
Function Bms1p and Tsr1p represent a new family of factors required for ribosome biogenesis. They are each independently required for 40S ribosomal subunit biogenesis. Bms1p, a protein required for pre-rRNA processing, contains an evolutionarily conserved G domain with five conserved polypeptide loops designated G1 through G5, which form contact sites with the guanine nucleotide or coordinate the Mg(2+) ion. Tsr1p lacks a P-loop and is not predicted to bind GTP.
Scope(s) Eukaryota
Example(s) Q07381 (TSR1_YEAST);

Propagated annotation [?]

Comments [?]

SIMILARITYBelongs to the TRAFAC class translation factor GTPase superfamily. Bms1-like GTPase family.

Keywords [?]

Gene Ontology [?]

case <FTGroup:1>
GO:0005525; Molecular function:GTP binding

Features [?]

From: PS51714
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="Bms1-type G #"
REGION 10 17 /note="G1 #" G-x(4)-G-K-[ST] 1
REGION 42 46 /note="G2 #" x(2)-T-x(2) 1
REGION 57 60 /note="G3 #" E-x(3) 1
REGION 110 113 /note="G4 #" T-H-x-D 1
REGION 144 146 /note="G5 #" 1

Additional information [?]

Size range 157-195 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined


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UniProtKB rule member sequences [?]