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annotation rule: PRU01051

General rule information [?]

Accession PRU01051
Dates 20-MAY-2020 (Created)
20-MAY-2020 (Last updated, Version 1)
Data class Domain
Predictors PROSITE; PS51714; G_BMS1
Name Bms1-type guanine nucleotide-binding (G) domain
Function Bms1p and Tsr1p represent a new family of factors required for ribosome biogenesis. They are each independently required for 40S ribosomal subunit biogenesis. Bms1p, a protein required for pre-rRNA processing, contains an evolutionarily conserved G domain with five conserved polypeptide loops designated G1 through G5, which form contact sites with the guanine nucleotide or coordinate the Mg(2+) ion. Tsr1p lacks a P-loop and is not predicted to bind GTP.

Propagated annotation [?]


Comments [?]

Similarity Belongs to the TRAFAC class translation factor GTPase superfamily. Bms1-like GTPase family.

Gene Ontology [?]

case <FTGroup:1>
GO:0005525; Molecular function: GTP binding.

Keywords [?]

GTP-binding
Nucleotide-binding
end case


Features [?]

From: PS51714
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       Bms1-type G #        
REGION     10     17       G1 #     G-x(4)-G-K-[ST]   1
REGION     42     46       G2 #     x(2)-T-x(2)   1
REGION     57     60       G3 #     E-x(3)   1
REGION     110     113       G4 #     T-H-x-D   1
REGION     144     146       G5 #         1

Additional information [?]

Size range 157-195 amino acids
Related rules None
Repeats 1
Topology Undefined
Example Q07381 (TSR1_YEAST)
Scope
Eukaryota
Comments None

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.


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UniProtKB rule member sequences [?]