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annotation rule: PRU01051 |
Accession | PRU01051 |
Dates | 20-MAY-2020 (Created) 20-MAY-2020 (Last updated, Version 1) |
Data class | Domain |
Predictors | PROSITE; PS51714; G_BMS1 |
Name | Bms1-type guanine nucleotide-binding (G) domain |
Function | Bms1p and Tsr1p represent a new family of factors required for ribosome biogenesis. They are each independently required for 40S ribosomal subunit biogenesis. Bms1p, a protein required for pre-rRNA processing, contains an evolutionarily conserved G domain with five conserved polypeptide loops designated G1 through G5, which form contact sites with the guanine nucleotide or coordinate the Mg(2+) ion. Tsr1p lacks a P-loop and is not predicted to bind GTP. |
Similarity | Belongs to the TRAFAC class translation factor GTPase superfamily. Bms1-like GTPase family. |
From: PS51714 | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
DOMAIN | from | to | Bms1-type G # | |||||||||
REGION | 10 | 17 | G1 # | G-x(4)-G-K-[ST] | 1 | |||||||
REGION | 42 | 46 | G2 # | x(2)-T-x(2) | 1 | |||||||
REGION | 57 | 60 | G3 # | E-x(3) | 1 | |||||||
REGION | 110 | 113 | G4 # | T-H-x-D | 1 | |||||||
REGION | 144 | 146 | G5 # | 1 |
Size range | 157-195 amino acids |
Related rules | None |
Repeats | 1 |
Topology | Undefined |
Example | Q07381 (TSR1_YEAST) |
Scope | Eukaryota |
Comments | None |
Eukaryota | [13] |