We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
ProRule PRU01055
View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU01055
General rule information
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| Accession | PRU01055 |
| Dates | 11-APR-2018 (Created)
22-NOV-2019 (Last updated, Version 3) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51718; G_DYNAMIN_2 |
Name | Dynamin-type guanine nucleotide-binding (G) domain |
| Function | Members of the dynamin GTPase family catalyze diverse membrane remodelling events in endocytosis, cell division, and plastid maintenance. The dynamin-type G domain consists of a central eight-stranded beta-sheet surrounded by seven alpha-helices and two one-turn helices. It contains the five canonical guanine nucleotide binding motifs (G1-5). |
| Scope(s) |
Eukaryota Bacteria |
| Example(s) | P21575; |
Propagated annotation
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Comments
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| SIMILARITY | Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. |
Keywords
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Gene Ontology
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| GO:0003924; Molecular function:GTPase activity |
| GO:0005525; Molecular function:GTP binding |
Cross-references
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| PROSITE | PS00410; G_DYNAMIN_1; 1; |
Features
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| From: PS51718 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="Dynamin-type G #" | |||||||||
| REGION | 11 | 18 | /note="G1 motif" | |||||||||
| REGION | 37 | 39 | /note="G2 motif" | |||||||||
| REGION | 113 | 116 | /note="G3 motif" | |||||||||
| REGION | 179 | 182 | /note="G4 motif" | |||||||||
| REGION | 213 | 216 | /note="G5 motif" | |||||||||
Additional information
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| Size range | 101-347 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Bacteria [6] Eukaryota [126] All [ 132 ]
- Retrieve set of proteins with 3D structure for this domain