ProRule PRU01055

General rule information [?]

Accession PRU01055
Dates 11-APR-2018 (Created)
22-NOV-2019 (Last updated, Version 2)
Data class Domain;
Predictors PROSITE; PS51718; G_DYNAMIN_2
Name Dynamin-type guanine nucleotide-binding (G) domain
Function Members of the dynamin GTPase family catalyze diverse membrane remodelling events in endocytosis, cell division, and plastid maintenance. The dynamin-type G domain consists of a central eight-stranded beta-sheet surrounded by seven alpha-helices and two one-turn helices. It contains the five canonical guanine nucleotide binding motifs (G1-5).
Scope(s) Eukaryota
Example(s) P21575 (DYN1_RAT);

Propagated annotation [?]

Comments [?]

SIMILARITYBelongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

Keywords [?]

Gene Ontology [?]

GO:0003924; Molecular function:GTPase activity
GO:0005525; Molecular function:GTP binding

Cross-references [?]


Features [?]

From: PS51718
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="Dynamin-type G #"
REGION 11 18 /note="G1 motif"
REGION 37 39 /note="G2 motif"
REGION 113 116 /note="G3 motif"
REGION 179 182 /note="G4 motif"
REGION 213 216 /note="G5 motif"

Additional information [?]

Size range 101-347 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined


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UniProtKB rule member sequences [?]