ProRule PRU01055
General rule information
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| PURL | https://purl.expasy.org/prosite/rule/PRU01055 |
| Accession | PRU01055 |
| Dates | 11-APR-2018 (Created)
22-NOV-2019 (Last updated, Version 2) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51718; G_DYNAMIN_2 |
Name | Dynamin-type guanine nucleotide-binding (G) domain |
| Function | Members of the dynamin GTPase family catalyze diverse membrane remodelling events in endocytosis, cell division, and plastid maintenance. The dynamin-type G domain consists of a central eight-stranded beta-sheet surrounded by seven alpha-helices and two one-turn helices. It contains the five canonical guanine nucleotide binding motifs (G1-5). |
| Scope(s) |
Eukaryota Bacteria |
| Example(s) | P21575 (DYN1_RAT); |
Propagated annotation
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Comments
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| SIMILARITY | Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. |
Keywords
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Gene Ontology
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| GO:0003924; Molecular function:GTPase activity |
| GO:0005525; Molecular function:GTP binding |
Cross-references
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| PROSITE | PS00410; G_DYNAMIN_1; 1; |
Features
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| From: PS51718 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="Dynamin-type G #" | |||||||||
| REGION | 11 | 18 | /note="G1 motif" | |||||||||
| REGION | 37 | 39 | /note="G2 motif" | |||||||||
| REGION | 113 | 116 | /note="G3 motif" | |||||||||
| REGION | 179 | 182 | /note="G4 motif" | |||||||||
| REGION | 213 | 216 | /note="G5 motif" | |||||||||
Additional information
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| Size range | 101-347 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Bacteria [6] Eukaryota [126] All [ 132 ]
- Retrieve set of proteins with 3D structure for this domain