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PROSITE entry PS51718


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General information about the entry

Entry name [info] G_DYNAMIN_2
Accession [info] PS51718
Entry type [info] MATRIX
Date [info] 01-MAY-2014 CREATED;
07-APR-2021 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00362
Associated ProRule [info] PRU01055

Name and characterization of the entry

Description [info] Dynamin-type guanine nucleotide-binding (G) domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=273;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=268;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.0734248; R2=0.0082282; TEXT='-LogE';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=47981.0000000; R2=0.0000000; PRIORITY=1; TEXT='Heuristic 0.5%';
/CUT_OFF: LEVEL=0; SCORE=1572; H_SCORE=47981; N_SCORE=15.0; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=538; H_SCORE=47981; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-32; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380;
...
                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-380; BD=-380;
/M: SY='Q';  M= -13, -75,  23,   1,  32, -21,  45,  -5,  -8, -66, -62, -52,  31,  55, -57,  44, -54, -65, -74, -55;
/M: SY='D';  M= -19, -75,  55, -54,  27, -74, -62,  15, -52,  22, -52, -57, -74,  11,  51, -61,   3,  -8, -75, -55;
/M: SY='D';  M= -16, -73,  51,  24, -73, -12,  49, -67, -54, -19, -63,  11,   3, -53,  -3,  21,  36, -15, -87, -64;
/M: SY='H';  M= -13, -70, -61,  -1,  -1, -70,  52,  -8,  22,  31, -50,   7, -70, -55,   3,  17,  25,  -9, -77, -56;
/M: SY='P';  M= -62, -80, -70, -61,   1, -68, -65, -59, -64, -22,  80, -69, 105, -63, -71,  16, -57, -64, -75, -65;
/M: SY='M';  M=   7, -73, -53,  46, -73, -68, -57, -64,  54, -64,  55,   3, -65,   7,  28, -10, -11,  -9, -77, -65;
/M: SY='V';  M= -59, -70, -84, -79,  12, -86, -81,  63, -77,  22, -38, -78, -78, -76, -78, -70, -56,  73, -76, -55;
/M: SY='V';  M=  42, -66, -79, -72,   3, -73, -75, -32, -72,  40, -42, -75, -77, -71, -73, -61, -55,  69, -77, -58;
/M: SY='F';  M=   4, -69, -83, -78,  75, -80, -77,  37, -76,  -8, -44, -76, -79, -78, -76, -67, -57,  63, -63, -42;
/M: SY='V';  M= -60, -69, -81, -77,  46, -83, -78,  44, -74,  21, -41, -74, -77, -76, -76, -66,  23,  66, -72, -50;
/M: SY='G';  M= -49, -77, -64, -76, -83, 103, -71, -91, -70, -86, -75, -50, -68, -67, -77, -49, -68, -84, -74, -78;
/M: SY='D';  M= -61, -79,  68, -45, -80,   5, -56, -76,   3, -75,  19,   5,  36,  40,  40, -10,   2, -74, -83, -68;
/M: SY='Q';  M= -60, -76,   6, -50, -62, -72, -56, -55, -51, -15,  53, -57, -69,  89,   1, -54,  38,   8,  58,  17;
/M: SY='S';  M= -46, -66, -54, -56, -75,  15, -58, -75,  20, -78, -70,  33, -65, -50, -56,  89,   4, -69, -82, -68;
/M: SY='N';  M=  43, -66,  40, -53, -75, -56, -59, -66, -55, -71, -66,  51, -67, -54,  -2,  48,  25,  -7, -86, -68;
/M: SY='G';  M= -49, -77, -64, -76, -83, 103, -71, -91, -70, -86, -75, -50, -68, -67, -77, -49, -68, -84, -74, -78;
/M: SY='K';  M= -63, -77, -55, -41, -79, -70, -58, -79, 110, -78, -66, -48, -63, -39, -24, -57, -57, -75, -72, -65;
/M: SY='S';  M= -42, -64, -56, -57, -73, -51, -60, -72, -57, -76, -69, -44, -63, -50, -62, 104,  30, -64, -83, -66;
/M: SY='S';  M=  45, -62, -59, -59, -72, -54, -64, -66, -58, -70, -64, -49, -63, -55, -64,  72,  69, -57, -82, -67;
/M: SY='V';  M= -60, -67, -80, -75,  45, -82, -73, -31, -73,  45,  32, -74, -78, -73, -74, -66,  25,  63, -71, -49;
/M: SY='I';  M= -65,  57, -85, -81, -47, -87, -78,  79, -78,  52, -35, -78, -79, -75, -79, -73, -60,   2, -75, -57;
/M: SY='N';  M= -61, -74, -34,  81, -80, -62, -48, -80, -43, -80, -71,  93, -64, -41,   4, -50, -54, -78, -87, -72;
/M: SY='A';  M=  71, -64, -62, -60, -67, -53,  29, -66, -60, -66,  28,   0, -67, -55, -63,  56, -48, -58, -74,  18;
/M: SY='L';  M= -67, -71, -85, -78,  46, -85, -69,  36, -77,  71,  52, -80, -81, -72, -75, -76, -63, -37, -65, -46;
/M: SY='I';  M=   6, -69, -81, -75, -49, -79, -74,  55, -74,  50,  28, -75, -77, -70, -75, -12, -56,  39, -76, -57;
/M: SY='G';  M= -54, -79, -60,  -3, -77,  84,  71, -87,  -9, -80, -69, -50, -68,  16, -64, -52, -67, -83,  50, -63;
/M: SY='F';  M= -11, -75,   0,  36,  55, -74,  21, -17,   0, -14, -56, -59, -70,  38,  34, -59,   2, -14, -68, -49;
/I:         I=-38; MD=-97;
/M: SY='D';  M= -15, -84,  42,  37, -86, -71, -58, -83,  35, -81, -72,   7,  34,  37,  39, -59, -62, -80, -84, -73; D=-38;
/I:         I=-38; MI=0; MD=-97; IM=0; DM=-97;
/M: SY='F';  M= -17, -71, -81, -76,  70, -80, -71,  38, -70,  20,  32, -74, -79, -72,   1, -20, -59,  39, -63, -43;
/M: SY='L';  M= -66, -70, -68, -70,  11, -74, -59, -42, -68,  69,  33,  56,   8, -65, -69, -67, -59, -49, -68,  20;
/M: SY='P';  M= -64, -86, -68, -59, -75, -11,  25,  32, -64, -67, -60, -68, 108,  15, -72, -63, -59, -14, -79, -72;
/M: SY='R';  M= -56, -73, -58,  20, -68,  -7, -59, -57,  -6, -15,  27,  10, -69,  13,  55,  32,  -4,  26, -79, -64;
/M: SY='G';  M= -10, -78,  42,  35, -75,  71, -60, -84, -54, -79, -72, -50, -67, -54,  26, -53, -64, -78, -73,  17;
/M: SY='M';  M= -53, -71, -61,  -8, -68,  29, -62,  18, -58, -58,  52,  11, -67,  49, -62,  40,  25,  11, -79, -64;
/M: SY='G';  M= -53, -74, -55,  -9, -78,  78, -60, -80, -57, -27, -68,  55, -69,  14,   2,   1, -60, -77, -78, -72;
/M: SY='P';  M=  -9, -77, -62,  -1, -68, -16,  70,  35, -62, -59,  45,   6,  71, -58, -66,  -1,   0, -55, -81, -61;
/M: SY='C';  M= -16,  82, -66,  22, -63,   6, -69,  17,  -6, -11,  55, -63, -71, -62, -67, -58,  24,  22, -82, -66;
/I:         I=-16; MI=0; MD=-40; IM=0; DM=-40;
/M: SY='T';  M= -72, -83, -81, -83, -86, -89, -90, -70, -80, -80, -78, -71, -83, -83, -87,  -7,  83,  10,-108, -85; D=-16;
/I:         I=-16; DM=-40;
/M: SY='R';  M= -17, -99, -87, -76,  26, -94, -77, -94,  -4, -87, -82, -79, -95, -67,  79, -81, -84, -90, -88, -73; D=-16;
/I:         I=-16; DM=-40;
/M: SY='R';  M= -21,  56, -79, -72, -82, -83, -74, -79, -55, -22, -73, -71, -87, -65,  70,  16,  -1, -26, -94, -78; D=-16;
/I:         I=-16; DM=-40;
/M: SY='P';  M= -72, -94, -70,  19, -91, -79, -78, -78, -70, -87, -78, -77, 100, -70, -80,  -7,  -3, -16, -91, -88; D=-16;
/I:         I=-16; DM=-40;
/M: SY='L';  M= -15,  32, -82, -79, -56, -85, -80,  41, -78,  46, -44, -76, -80, -76, -80, -67,  38,  19, -83, -65; D=-16;
/I:         I=-16; DM=-40;
/M: SY='H';  M= -68,  29, -72, -13,   7, -83,  57,  38,  -5,   5, -52,   2, -79, -68, -69, -68,  -2,  23, -78,  14; D=-16;
/I:         I=-16; DM=-40;
/M: SY='C';  M= -69,  74,   0, -11, -57, -88, -77,  45, -78,  46,  14, -77, -84, -74, -80, -75, -65,  -2, -84, -66; D=-16;
/I:         I=-16; DM=-40;
/M: SY='Q';  M=   8, -78, -64,  -7,  26, -73,  26, -73,  -7, -70, -64, -58, -72,  71,  21, -54,  50, -69, -78, -60; D=-16;
/I:         I=-16; DM=-40;
/M: SY='M';  M= -69, -76, -80,  -5,   5, -87,  29, -42, -71,  57,  65, -78, -83, -68,  -6, -76, -67,  15, -78, -56; D=-16;
/I:         I=-16; DM=-40;
/M: SY='Q';  M= -61, -76, -68,  -7, -69, -75, -67,  12,  16,   4,  30, -62, -73,  50, -60,  31,  25,   8, -83, -66; D=-16;
/I:         I=-16; DM=-40;
/M: SY='N';  M= -13, -78, -56,  -1,  -7, -69,  22, -68,  -7, -73, -67,  74,   9, -57,  33, -59, -60,   9, -81,  13; D=-16;
/I:         I=-16; DM=-40;
/M: SY='N';  M= -60, -75,  53,  33, -72,  16, -54, -74, -55, -27, -68,  61,  37, -53, -63,   8,  -5, -73, -80,  12;
/M: SY='P';  M=  -7, -74, -65, -62, -74,  54, -68,  -8, -14, -25, -62, -57,  60,  14, -67,  10,  27, -15, -77, -71;
/M: SY='S';  M= -54, -70,   3, -52, -73, -61,  31, -12,  22, -71, -64,  28,   7,  14,   6,  56,  50, -63, -83, -64;
/I:         I=-8; MD=-20;
/M: SY='D';  M= -80,  28,  42,  33,  -2, -86, -76, -91, -12, -31, -85,   7,  -9, -70, -77,  -6, -74, -89, -99, -82; D=-8;
/I:         I=-8; MI=0; MD=-20; IM=0; DM=-20;
/M: SY='C';  M=  10,  62, -50,  60, -77, -14,  30, -77,  31, -74, -67, -53, -64,  15, -52,  30,   2, -69, -81, -68;
/M: SY='F';  M= -15, -73, -62,  36,  59,   9, -65, -53,  -7, -20, -57,  -1,  -6, -61, -64, -11, -59,  29,  48,   8;
/M: SY='H';  M=  21, -76, -51,  54, -70, -15,  56,  -7,  17, -69, -62,   1,  33, -48,  -3, -54,   3, -65, -76,  11;
/M: SY='V';  M=  24, -71, -70, -13, -62, -17, -70,  13,  19,   4,  29, -66,  34, -61, -63,  -9, -55,  48, -78, -64;
/M: SY='W';  M= -62,  30,  -3, -66,  28, -14, -66,  34,  17, -11,  23,   3, -74, -64,  -5, -61,  19,  16,  39,  19;
/M: SY='M';  M= -18,  25, -69, -66, -56, -74,  53,  17,  -3,  -3,  69,   2,   9, -62, -64, -60,  22,  30, -76,  18;
/M: SY='H';  M= -64, -75,  26,  31, -58, -74,  91,  -7, -58,  35, -49, -55, -70, -53,  -4, -10,   4, -59, -79,  12;
/M: SY='G';  M= -57,  20, -64, -62,  54,  56, -59, -71,  -6, -66, -63,   4, -72,  52, -61,  18, -60, -70, -61,  32;
/M: SY='P';  M= -10, -75, -56,  20, -70, -65, -60,  12,  33,   3, -57,  25,  50,  33, -54,  33, -53, -60, -77, -67;
/M: SY='D';  M= -62, -77,  92, -38, -82, -65, -54, -79,   2, -78, -72, -41, -66,  38,  29,  11,  26, -75, -90, -67;
/M: SY='E';  M= -63, -77,  45,  56, -65, -13, -52, -71,  26, -18,  16,  45,  11, -48, -53, -57, -58, -71, -73,  39;
/I:         I=-21; MD=-53;
/M: SY='W';  M= -75, -89,  23,  -9,   4, -81,  27,  -9,  30, -80, -76,   5,   2, -65,  -7,  -6,  -4, -78,  48, -67; D=-21;
/I:         I=-21; MI=0; MD=-53; IM=0; DM=-53;
/M: SY='K';  M= -66, -81, -73, -10, -74, -11, -76,  29,  32, -25,  26, -66, -77, -65, -66,  28,  22, -20, -88, -73; D=-21;
/I:         I=-21; DM=-53;
/M: SY='Y';  M= -61, -77,   2,  20, -53, -10, -52, -66,  45, -20, -59, -56,   3,   9,   7,  18, -58, -23, -59,  74;
/M: SY='E';  M= -59, -73, -57,  45,  -5, -73, -63,  14,  -2,   7,  25,   0,  27,   8, -61,  -1,  26,  14, -77, -61;
/M: SY='I';  M= -57, -70, -64,  -1,   4, -73, -68,  43,  32, -11, -50,  10, -70, -59, -59,  17,  31,  39, -77, -59;
/M: SY='D';  M= -11, -75,  80,   5,   4, -64,  23, -73, -10, -71,  22, -46,  33, -54, -61,  30,  -2, -70, -84, -62;
/I:         I=-45; MD=-115;
/M: SY='L';  M=  19, -73,  -7, -17,  -4,  15, -70, -52, -69,  38, -52, -66,  34, -66, -73,  -2,  -4,  10, -77, -64; D=-45;
/I:         I=-45; MI=-115; IM=-115; DM=-115;
/M: SY='N';  M=  11, -70,  -5, -15,  -2, -11,  26,  20, -61, -20, -56,  47, -70, -57, -65,  42,  -2,  -6, -74,  20;
/M: SY='E';  M=  34, -75,   4,  62, -79, -67,  14, -71,  32, -71, -64, -54, -63,  55,   6, -52, -58,  -8, -78, -66;
/M: SY='L';  M= -15, -71,   2,  13,  11, -81, -69,  42, -70,  51,  32, -72, -75, -66, -72, -68, -59,  25, -73, -54;
/M: SY='A';  M=  49, -70,   6,  -7, -68, -12, -64,  -6,  -4,   3, -55, -59, -70,  13,  36, -53,  -3,  12, -78, -65;
/M: SY='H';  M=  11, -75,  -1,  14, -74, -67,  81, -67,  53, -69, -61, -52,   4,   6,   8,  -3, -57,  12, -82, -59;
/M: SY='D';  M=  42, -73,  44,  44, -70, -63, -57, -67, -50, -22, -62, -54, -67,  19,  22,  16, -55, -15, -76,  13;
/M: SY='I';  M= -64, -75, -75,  -8, -51, -82,  27,  74, -71,  45,  22, -71,   9, -66, -73,  -5, -59, -34, -75, -56;
/M: SY='E';  M=  -9, -75,   7,  56, -72, -69,  24, -10, -47, -25, -60,   3, -66,  36,  35,  19, -56,  12, -81, -64;
/M: SY='M';  M=  17, -75,  23,  -3, -63, -69, -58, -58,  -6,   7,  46, -60,  33,  12,  41, -10, -58,  -7, -73,  16;
/M: SY='E';  M=   2, -77,  28,  53, -77, -10, -57, -76,  -1, -23, -66, -53,  10,  12,  49,  23, -57, -71, -79, -68;
/M: SY='N';  M= -11, -68, -59, -61,  48, -67, -58, -55,  17,  -1,  56,  58, -70,   7, -58, -52,  53, -56, -71, -51;
/M: SY='N';  M= -58, -74,  35,  35, -73, -14, -56, -66, -49, -19,  24,  43,  11,  13,  28,  33, -53,  -8, -83, -67;
/M: SY='K';  M=  20, -72,   2,  -5,   5, -65, -59, -65,  54, -22,  17,  33,  12, -50,  22,   0, -55, -22, -75, -62;
/M: SY='W';  M= -18, -72, -73, -67,   5, -17, -66,  11,  -9,  44, -47, -66,   8, -62,  -5,  36, -57, -13,  56,  12;
/M: SY='A';  M=  53, -68, -56,  39, -72, -60, -64, -59, -58, -24, -60,   9,  33, -54, -64,  21,  18,  12, -80, -70;
/M: SY='K';  M=  11, -74,   0, -57, -66,  40, -62,  -3,  46, -22,  26, -54,   1,  13, -54,  -8,   1, -61, -71,  17;
/M: SY='E';  M= -10,  27, -61,  35,  33, -17, -63, -56,  -8,  18,  24, -61, -70, -55,  22,  15,  16, -10, -72, -56;
/M: SY='G';  M=  10, -73,   1, -60, -71,  54, -64,  -6,  32,   1, -61,  28,   7, -58, -59,  -9,  -4, -63, -77, -69;
/M: SY='Q';  M= -60,  29, -59,  -7, -67, -16, -56,  17,  26, -60,  20,  31, -71,  77,   7, -56, -58,  13, -73,  13;
/M: SY='Y';  M=  23, -71,  25,   0, -63,  18, -57, -64, -54, -21, -61,  37, -69, -55,  20,  -3,  23,  -9, -72,  39;
/M: SY='V';  M= -16, -72,  -5, -63,  33, -73,  29,  29, -62, -51, -51,   8,   7,  16,  -5,  -6,   0,  53, -76, -54;
/M: SY='S';  M= -57, -69, -63,  -9,  28, -68, -62,   0,  19,  21,  28,  33, -72, -58, -60,  46, -51,  25, -74, -55;
/M: SY='D';  M= -11, -76,  50,  35, -72, -65,  22, -14, -57, -22, -65,  11,  49, -53, -64,  30,   5, -66,  49, -64;
/I:         I=-36; MD=-90;
/M: SY='P';  M= -18, -95,  -5, -76, -88, -13, -81, -86,  17, -92, -86,  -1,  28, -76, -77,  16, -73, -14, -94,  10; D=-36;
/I:         I=-36; MI=0; MD=-90; IM=0; DM=-90;
/M: SY='E';  M=   2, -76, -52,  55, -65, -72,  26,  17,  35, -23, -57,   9, -67, -46,  41, -58, -59, -17, -74,  13;
/M: SY='P';  M= -66, -82, -65,  -3,  31, -72, -66, -64,  15,   2, -60, -67, 100, -61,   1, -62,   2, -67, -72, -63;
/M: SY='I';  M=   8,  57, -81, -76, -53, -80, -77,  80,  -9,  16,  30, -72, -75, -70, -73, -67, -58,   3, -76, -60;
/M: SY='H';  M= -14,  32, -59,   1,   0,  -8,  57,  -8,  -4, -64, -59,   0, -68,   6,  -4,  34,  33, -14, -75,  14;
/M: SY='L';  M= -11, -69, -74,  -4, -50, -78, -70,  39, -70,  57,  23, -71, -74, -65, -72,  -8,  19,  17, -76, -58;
/I:         I=-29; MD=-75;
/M: SY='S';  M= -10, -79, -59,  35, -83, -70,  13, -82,  -3, -81, -73, -57, -71,  16,  34,  52,  23, -75, -88, -72; D=-29;
/I:         I=-29; MI=0; MD=-75; IM=0; DM=-75;
/M: SY='V';  M= -19, -80, -85, -10, -63, -14, -87,  43, -82,  19, -51, -83, -85, -79, -84, -75, -66,  53, -88, -70; D=-29;
/I:         I=-29; DM=-75;
/M: SY='E';  M= -71,  28, -64,  45, -74, -82, -69, -73,  28,  16, -66, -71,  36,  12, -62, -13, -68, -74, -82,   3; D=-29;
/I:         I=-29; DM=-75;
/M: SY='H';  M= -68, -85, -66,  -3,   0, -10,  57, -82, -16, -78, -71,   8, -80, -60,  21,  37, -65, -80, -72,  57; D=-29;
/I:         I=-29; DM=-75;
/M: SY='P';  M=  15, -83, -68, -64, -84, -71, -68, -80,  21, -26, -72,  30,  48, -60,  40,  15, -63, -77, -88, -78; D=-29;
/I:         I=-29; DM=-75;
/M: SY='H';  M= -61, -74,  -4, -66, -49,  35,  64, -54, -64,  37, -49, -59, -74, -62,  -8, -59,  20,  -8, -65,  60;
/M: SY='C';  M= -17,  71,   2, -62, -58, -75, -67,  22, -62,   8, -50, -64,  10,  36,  -4, -59,  21,  31, -76,  19;
/M: SY='P';  M= -61, -77,  27,   2, -66,  -9, -60, -61,  -6,  15, -58,   6,  72,  16, -63,  -9,   2, -14, -75,  15;
/M: SY='D';  M= -62, -76,  79, -44, -82, -10, -51, -81, -48, -82, -73,  74,   2,  16,  29,  -1, -54, -79, -91, -70;
/M: SY='L';  M= -63, -70, -84, -78, -45, -85, -72,  47, -76,  65,  58, -79, -79, -71, -75, -74, -59,  34, -74, -55;
/M: SY='T';  M=  -8, -65, -60,  -5, -65, -66, -67, -48,  -9, -13, -55,   5, -66, -59, -63,  32,  76,  40, -84, -65;
/M: SY='L';  M= -67, -72, -85, -79,  13, -87, -72,  60, -78,  72,  18, -80, -80, -72, -77, -76, -62, -33, -69, -51;
/M: SY='I';  M= -60, -72, -84, -80, -48, -86, -78,  76, -76,  11,  30, -77, -77, -74, -77, -71, -56,  61, -74,  11;
/M: SY='D';  M= -67, -81, 117,  10, -88, -65, -53, -86, -54, -84, -83, -36, -66, -53, -63, -56, -57, -83,-102, -71;
/M: SY='T';  M=  -9, -65, -64, -63, -61, -65, -66, -53, -62,  38, -51, -55,  13, -60, -67,  51,  74, -52, -80, -63;
/M: SY='P';  M= -66, -92, -67, -55, -86, -68, -70, -74, -63, -84, -70, -73, 128, -66, -75, -64, -59, -79, -79, -83;
/M: SY='G';  M= -48, -76, -64, -75, -82, 101, -70, -90, -69, -86, -75, -50, -68, -66, -76,   2, -65, -83, -74, -77;
/M: SY='I';  M= -63, -72, -81, -76,  27, -84, -73,  51, -75,  44, -38, -76,   9, -73, -76, -69,  -3,  44, -69,   9;
/I:         I=-26; MD=-67;
/M: SY='N';  M= -65, -76,  52, -61, -70, -71, -65,  44, -65, -19, -60,  60, -74, -64, -71,  -1,  30, -12, -92, -69; D=-26;
/I:         I=-26; MI=0; MD=-67; IM=0; DM=-67;
/M: SY='Q';  M=  10, -85,  -2,  -2,   0, -82, -75, -67, -15,  -2, -67, -72, -84,  30,  14,  -5, -69,  11, -87, -72; D=-26;
/I:         I=-26; DM=-67;
/M: SY='T';  M= -65, -77,  -1, -67, -72, -78, -73,  -1, -10, -18, -62,  10,   6, -66,  18,  -7,  50,  30, -91, -72; D=-26;
/I:         I=-26; DM=-67;
/M: SY='P';  M=  21, -80, -66,  16, -82, -13, -72, -14,  -9, -74, -69, -65,  41,  11,   2,  -4,  24,  -9, -86, -76; D=-26;
/I:         I=-26; DM=-67;
/M: SY='E';  M=   7, -71, -59,  35, -67,  11, -65,   0,  19, -17,  21, -58, -66,  15, -58,  -5,  27,  31, -79, -65;
/M: SY='Q';  M=   8, -75,  40,   1,   1,  21, -58, -68,  17,   1, -60,  -3, -68,  57,   1, -53,   2, -67, -76, -62;
/M: SY='D';  M= -12, -74,  67,  -4, -82,  47, -56, -82,  -2, -81, -73,  47, -67,  17, -59,  19, -55, -77, -85, -71;
/M: SY='Q';  M= -57, -77,   6,  55, -75, -68, -52, -68, -45, -22,  54, -53, -64,  86,   3,  30, -56, -68, -77, -63;
/I:         I=-15; MD=-37;
/M: SY='P';  M=   8, -97, -83, -74, -98, -81, -82, -93, -67, -96, -86, -80,  71, -73,  39,  18, -73, -89, -97, -91; D=-15;
/I:         I=-15; MI=0; MD=-37; IM=0; DM=-37;
/M: SY='G';  M= -19,-103, -86, -18, -99,  39, -89,-106,  29,-105, -95, -80,  -1, -80, -79, -79, -88,-101, -96,  -5; D=-15;
/I:         I=-15; DM=-37;
/M: SY='Y';  M= -88,-100,  -5,  13, -66, -92, -67, -90, -74, -88, -83,  32, -95, -74,  -4, -79, -12, -91, -75,  75; D=-15;
/I:         I=-15; DM=-37;
/M: SY='E';  M= -18, -96,   3,  34, -99, -87,  28, -96,  28, -93, -84, -70,  10,  25, -65, -71,  -1, -91, -99, -84; D=-15;
/I:         I=-15; DM=-37;
/M: SY='I';  M= -84, -93,-105,-101,  32,-106, -96,  66, -96, -13,  30, -95, -95, -94, -97, -92, -78,  -6, -85, -65; D=-15;
/I:         I=-15; DM=-37;
/M: SY='E';  M= -15, -92, -72,  18,   3, -11, -76, -88,  10, -30, -80,   9, -86,  13,  -9,   7, -74, -86, -91, -79; D=-15;
/I:         I=-15; DM=-37;
/M: SY='D';  M=   8, -90,  38,  20, -98, -26, -78, -95,  -5, -95, -89, -66, -82, -68, -76,  31,  -8, -87,-102, -88; D=-15;
/I:         I=-15; DM=-37;
/M: SY='M';  M= -63,  32, -81, -71, -51, -79, -67,  23,  -5,  28,  99, -73, -75,   8, -65, -70, -61,  19,  80, -52;
/M: SY='I';  M= -58,  57, -77, -75, -54, -78, -77,  63, -72,  23, -43, -68, -75, -70, -75,  18,  24,  39, -80, -61;
/M: SY='K';  M=   5, -72,  42,  20, -72, -66, -57, -67,  43,  -3,  11,  12, -66,  18,   3,  -4,  28, -64, -81, -65;
/M: SY='W';  M=  12, -75, -56,  29, -73, -11, -61, -76,  50, -75, -67, -53, -65,  55, -47,  44, -55, -72,  86, -60;
/M: SY='Y';  M= -68, -76, -73, -69,  58, -79,  27, -48,  -7,  16, -46, -70, -80,  14, -62, -67, -63,  13, -45,  95;
/M: SY='C';  M=  21,  74, -79, -75,   8, -75, -72,  48, -72,  19,  68, -70, -76, -70, -74, -62,   4,  -3, -75, -57;
/M: SY='Q';  M=  12, -73,   8,  32, -72, -64, -56, -65,   2,   1,  26,   7, -66,  64,   1,  28,  -5, -64, -78, -64;
/M: SY='R';  M= -19,  32,  42, -51, -78, -66,  51, -79, -44, -77, -68,  34,  55, -51,  67,  -1, -58, -76, -86, -66;
/M: SY='Q';  M=  45,  28, -58,  -8, -78, -60, -60, -67,  18, -71, -63,  32,  47,  61, -55,  -3, -54, -10, -79, -70;
/M: SY='D';  M= -62, -76,  71,  53, -80, -62,  68, -82, -50, -79, -71,  60, -65, -46, -57,  16, -54, -79, -93, -64;
/M: SY='R';  M=  35, -71, -63,  19,   3, -68, -64, -10, -49, -14, -55, -62, -70, -53,  60,   8,  -4,  28, -76, -61;
/M: SY='I';  M= -65, -74, -84, -81,  46, -87, -80,  90, -77,   7, -38, -74, -76, -76, -79, -70,   4,   5, -67, -48;
/I:         I=-45; MD=-115;
/M: SY='I';  M= -70, -80,  24, -76,   9, -88, -80,  64, -80,  29, -47, -75, -83, -77, -82, -14, -64,  15, -81, -61; D=-45;
/I:         I=-45; MI=-115; IM=-115; DM=-115;
/M: SY='L';  M= -11, -69, -83, -76, -45, -83, -73,  23, -76,  72, -33, -80, -81, -72, -75, -71, -59,  43, -75, -56;
/M: SY='V';  M=  19,  58, -78, -74,  45, -75, -75, -34, -73,   8, -47,  -9, -80, -75, -74, -63, -55,  71, -74, -53;
/M: SY='V';  M= -15,  30, -82, -77,  34, -80, -77,  44, -75,  30, -41, -75, -79, -74, -76,  -8, -56,  60, -73, -53;
/M: SY='N';  M= -61, -73,  47,  37,  28, -68, -56, -58, -55,  -2,  23,  48, -69,  38, -60, -10,  -7,   7, -78, -57;
/M: SY='P';  M=  35, -73,   5,  -2, -70, -63, -61, -62, -55, -68, -62, -58,  58,  33,  -2,  28,   5,  12, -75,  16;
/M: SY='S';  M=  37,  29,   3,  35, -73,  -7,  29, -63, -58, -68, -63, -53, -65, -54, -64,  43,  28,  12, -84, -67;
/M: SY='S';  M= -50, -67,  -1, -52, -76, -54, -54, -74,  23, -77, -68,  65, -65,  17, -53,  76,  23, -69, -85, -67;
/M: SY='Q';  M=  10, -67, -66, -61, -61, -69, -65, -41, -61,  22,  17,  11, -71,  51, -64,  -4,  39,  50, -80, -62;
/M: SY='D';  M= -18, -78,  85,  46, -76,  -7, -58, -68,  -1,  -1, -66, -48,   7, -52, -60, -57, -58, -11, -87, -69;
/M: SY='W';  M=  -9,  28, -70, -70,  -6,  -7, -70,  17, -66,  -3,  22,  31, -73, -64, -70,  33,   0,  -5, 109, -52;
/M: SY='T';  M=  29,  25, -56,  20, -74,  -7,  29,  -6,  -4, -68, -62,   6, -66,  36,   3,  21,  37, -61, -81, -65;
/M: SY='N';  M= -12, -68,   4, -62,   6, -65, -61,  16, -58,  18, -53,  56, -71, -59,   2,  33,  33,  -6, -79, -59;
/I:         I=-38; MD=-97;
/M: SY='S';  M= -11,  16,   5,  35, -79, -12, -66, -74, -61, -74,  22, -54, -68, -56, -68,  57,  48, -68, -89, -73; D=-38;
/I:         I=-38; MI=0; MD=-97; IM=0; DM=-97;
/M: SY='E';  M= -57, -75,  -2,  69, -72, -69, -59,  16,  19, -24, -62, -54, -63, -44,  24,  42,   1, -60, -79, -66;
/M: SY='M';  M=  46, -69, -63,  -1,   6, -63,  24, -56, -57, -13,  54,   6, -69,  14,  -1,  11,   0,  -6,  47, -56;
/M: SY='F';  M= -62, -71, -68,  -1,  45, -15, -65, -13,  -7,  40, -47, -64, -74, -60,  38,  -4,  26,  -5, -69, -51;
/M: SY='F';  M= -64, -78,  43,  38,  44, -72, -55, -69,  28, -64,  28, -54,   4,  13,  38, -10, -60, -69, -67,  15;
/M: SY='L';  M=   3, -71, -73,  -3,  30, -78,  23,  18,  -5,  51,  44, -71, -76, -63, -66, -67, -61,  -3, -66,  16;
/M: SY='A';  M=  42, -69,   2,  -5,   8, -68, -69,  19,  -8,   6, -51, -63, -71, -60,  -2,   8, -54,  39, -76, -59;
/M: SY='K';  M= -59, -74, -61, -52, -69, -70, -59,  -3,  65, -62,  24,   7, -69,  10,  50,  18, -54,  27, -77, -63;
/M: SY='Q';  M=  34, -73, -52,  41, -69, -64, -55, -67,  43,   1, -58,  32, -66,  57, -47, -52, -57, -65, -72,  12;
/M: SY='I';  M=  34, -69, -72,  -8, -54, -72, -69,  43,  -7,  24,  30, -69, -72, -63, -67,  -4, -55,  34, -73,   9;
/M: SY='D';  M= -62, -77,  92, -38, -81, -65, -56, -75,  56, -77, -73, -42, -66, -49,   1,  18, -54, -11, -88, -68;
/M: SY='P';  M= -61, -79, -64, -62, -66,  29, -63, -65, -16,  15, -59,   8,  87, -62,  -5,  -9,   1, -67, -72,  18;
/M: SY='E';  M= -57, -77,   3,  62, -80, -66,  30, -79,  21, -75, -67, -49, -63,  55,  28,  43, -10, -74, -80, -65;
/M: SY='G';  M= -57, -74, -60,  23,  24,  49, -63, -66,  44,  18, -58, -56, -69, -54,   3,  17, -60, -66, -70, -59;
/M: SY='S';  M= -56, -73,  43, -51, -70, -65, -61, -62,  19,  10, -60, -52,  49,   1,  -4,  53,  -3,  -9, -81, -66;
/M: SY='R';  M= -65, -78, -57, -52, -74, -70,  30, -75,   5, -25, -61,  48,  10,  19,  89, -56,  -2, -73, -80, -62;
/M: SY='T';  M= -55, -66, -68, -68, -57, -73, -71,  47, -65,   8,  23, -58, -67, -65, -70,  21,  78,  16, -81, -61;
/M: SY='I';  M= -68, -75, -80, -77,  73, -84, -70,  74, -66, -17, -44, -72, -77, -71,  26, -69,  -2, -36, -58,  21;
/M: SY='F';  M= -23, -72, -81, -80,  67,  30, -76,  55, -76, -13, -46, -71, -77, -77, -77, -66, -60,  41, -64, -46;
/M: SY='V';  M= -58, -69, -84, -78, -49, -86, -80,  47, -76,  40, -37, -79, -79, -75, -77, -70, -55,  78, -80, -58;
/M: SY='N';  M= -60, -69, -68, -72,  33, -73, -67,  29, -68,  32, -44,  57, -78, -68, -71,  -7, -54,  53, -75, -54;
/M: SY='N';  M= -56, -65, -45, -58, -73, -13, -53, -69,  -6, -75, -66,  95, -66, -54, -58,  -3,  74, -65, -90, -69;
/M: SY='K';  M= -14, -77, -57, -43, -78, -69, -58, -79, 100, -77, -65, -50, -65, -40,  44, -56, -58, -73, -73, -65;
/M: SY='W';  M=  21, -75, -85, -76,  80, -74, -75,  -7, -73,  14, -51, -78,   1, -75, -75, -68, -65,  -5, 111, -35;
/M: SY='D';  M= -68, -81, 114, -33, -85, -65,  57, -86, -55, -82, -79, -36, -67, -53, -62, -56, -58, -83,-103, -65;
/M: SY='Q';  M=   8, -71, -55, -52, -67, -63,  27, -61,  19,  23,  12,  59, -70,  65, -52,   1,   0, -62, -79, -61;
/M: SY='I';  M=  32, -69, -70, -63, -61, -69, -67,  34,  -5,  10,  17, -63, -71,  15,  20,  16,   0,  26, -77, -62;
/M: SY='D';  M=  34, -73,  49,  24, -69, -67, -62,  -6, -52,   3, -57, -57,  -5, -54,  39,  -3, -56,  11, -81, -66;
/I:         I=-42; MD=-106;
/M: SY='K';  M= -15, -83,  26,  40, -86, -74, -65, -85,  43, -84, -76, -57,   7, -52,  26,  17,   3, -79, -88, -76; D=-42;
/I:         I=-42; MI=-106; MD=-106; IM=-106; DM=-106;
/M: SY='N';  M= -64, -82, -55,  43, -84,  43, -64, -84,  18, -23, -74,  48, -73,  12, -61,  -7, -65, -82, -86, -78; D=-42;
/I:         I=-42; DM=-106;
/M: SY='T';  M= -59, -71,   7,  22,  43, -71, -63, -56, -60,  25, -54, -58,  28,   8, -65,  17,  58, -57, -72, -54;
/M: SY='Q';  M=  -9, -77,  25,  44, -77, -67, -56, -11,  -4, -31, -63, -53,  10,  59,  39,  31, -56, -67, -79, -66;
/I:         I=-36; MI=0; MD=-90; IM=0; DM=-90;
/M: SY='C';  M= -17,  74,  42, -55, -70, -65, -57, -70,  13, -67,  54,  49, -73,  15, -59,  20, -10, -68, -83,  10; D=-36;
/I:         I=-36; DM=-90;
/M: SY='P';  M=  29, -72, -65,  -2, -65,  -7, -65,  -6,  18,  18,  22, -62,  35, -56,  20,  -5,  -1, -12, -76, -65;
/M: SY='R';  M= -16, -76,  40,  45, -74, -16, -56, -68, -44, -66,  54, -53, -67,  17,  59,  20, -57, -16, -80, -65;
/M: SY='D';  M= -18, -77,  84,  -1, -76, -66, -55, -73,   0,   0, -66, -46, -69,  17,  44,  13, -57, -71, -85, -66;
/M: SY='V';  M=  11, -68, -82, -76, -54, -80, -84,  55, -74, -40, -42, -76, -76, -75, -77, -64, -53,  85, -83, -61;
/I:         I=-31; MD=-79;
/M: SY='Q';  M= -74, -88,  -3,  19, -84, -80,  22, -81,  20,  -1, -71,  34, -80,  37,  25, -19, -70, -82, -92, -74; D=-31;
/I:         I=-31; MD=-79;
/M: SY='K';  M=   6, -88,   2,  21, -88, -81, -70, -23,  43, -80, -74, -66, -78,  16,  39, -68, -70, -15, -89, -78; D=-31;
/I:         I=-31; MI=0; MD=-79; IM=0; DM=-79;
/M: SY='Q';  M= -80, -91,  -6, -75,  30, -92, -80,  -5, -79,  14, -65, -79, -92,  52, -80, -15,  -2, -23, -87, -68; D=-31;
/I:         I=-31; DM=-79;
/M: SY='H';  M= -18, -73, -71,  -9, -43, -79,  70,   2, -69,  57, -39, -69, -78, -62, -67, -67, -62,  15, -65,  59;
/M: SY='S';  M= -52, -71, -58,  18, -70,  47, -59, -66, -57,   1,  51,   2, -67,  12,  -5,  59, -53, -65, -77, -66;
/M: SY='N';  M=  27, -72, -51,  34, -75,  29, -59, -75, -56, -77, -68,  52,  49, -54, -64,  22,   0, -70, -77,  -1;
/M: SY='R';  M= -60, -76, -63,  -6, -65,  26, -61, -63,  31,  17, -56, -58,  36,   8,  40,  -6,   2, -22, -72,   9;
/M: SY='C';  M= -12,  70, -70,  -7,  32, -18, -68,  -6, -13,  28,  28, -63, -73, -65, -68,  -1,  38, -10, -74, -56;
/M: SY='W';  M= -63, -75, -76, -73,  47, -18, -66,  20, -66,   1,  29,   3,   1, -67,  -3,  -8, -61,  25,  86,  37;
/M: SY='P';  M=  24, -76, -57,  -6, -79,  -6,  49, -76,  20, -76, -66,  10,  67,  13,  18,  22, -55, -72, -80, -67;
/M: SY='L';  M= -10, -72,  27, -61,  28, -10, -61, -49, -10,  54,  30,  22, -76,   8,  -4, -63, -60, -54, -71, -54;
/M: SY='C';  M=  25,  33,   1, -57, -67, -10, -65,  -7,  33,  16, -56, -58,  12, -56,  32, -10,  19, -57, -78, -66;
/I:         I=-8; MD=-21;
/M: SY='K';  M=  10, -73, -67, -58, -70, -72, -67,  14,  53, -60,  17, -60, -70,  12,  19,  -5,  24,  28, -80, -66; D=-8;
/I:         I=-8; MD=-21;
/M: SY='D';  M= -68, -86,  52, -66,   6,  39, -75, -76, -74, -21, -75, -62,  28, -74, -81,  -8,   0, -16, -89, -74; D=-8;
/I:         I=-8; MD=-21;
/M: SY='F';  M= -81, -89, -85,  -7,  65, -13, -71, -12, -82,   4, -61, -84,   8, -81, -83, -80, -77, -67, -60,  61; D=-8;
/I:         I=-8; MD=-21;
/M: SY='F';  M= -78, -87, -92, -85,  41, -95, -80, -12, -84,   4,  19, -86,  -2,  11, -84, -80,   1,  24, -77,  18; D=-8;
/I:         I=-8; MD=-21;
/M: SY='H';  M= -74, -91, -84, -83,   5,  33,  52,  11, -81, -73, -70, -74, -87,  12, -83, -73,   0,   8,  46, -67; D=-8;
/I:         I=-8; MD=-21;
/M: SY='V';  M=   7, -83,  -3, -83,  27, -87, -88,  -2, -85, -15, -64, -81, -89, -85, -88, -13,  -4,  42, -89, -68; D=-8;
/I:         I=-8; MD=-21;
/M: SY='V';  M= -22, -86, -91, -84,   6, -90, -84, -10, -15,  14, -61, -86,  10, -82, -83, -11, -71,  37, -83,  15; D=-8;
/I:         I=-8; MD=-21;
/M: SY='P';  M= -69,  23, -78, -75, -89, -78, -82, -75, -77, -86, -80,  -5,  69, -76, -85,  44,  -8,   9,-100, -88; D=-8;
/I:         I=-8; MD=-21;
/M: SY='T';  M= -76,  31, -79, -75,   1, -88, -80, -14,  27, -26, -71,   4, -86, -73,  16, -69,  41, -10, -92, -74; D=-8;
/I:         I=-8; MD=-21;
/M: SY='G';  M=  11, -86,  -6, -73,  -1,  24,  24, -90, -11, -87, -81,   2, -84, -71,  -1,  14, -10, -84, -92, -76; D=-8;
/I:         I=-8; MD=-21;
/M: SY='Q';  M= -76, -98, -76, -63,-101, -19, -73, -95,  -2, -93, -81, -70,  -2,  79,  19,  -6,  -5, -93, -94, -83; D=-8;
/I:         I=-8; MD=-21;
/M: SY='S';  M= -80, -99,  -6,  -6, -99, -90, -84, -89, -17, -91,  24, -78, -93,   5,   1,  37, -76, -18,-107, -90; D=-8;
/I:         I=-8; MI=0; MD=-21; IM=0; DM=-21;
/M: SY='N';  M= -82,-100, -81, -13, -96,  25, -89,  22,  -6, -90, -86,  28, -94, -82, -87, -11, -82, -81,-104, -94; D=-8;
/I:         I=-8; DM=-21;
/M: SY='Q';  M= -76, -92,   4, -15, -94, -83, -77, -83, -75, -30, -82,  32, -90,  35, -80,  29, -10, -14,-106, -87; D=-8;
/I:         I=-8; DM=-21;
/M: SY='P';  M= -14, -91,  40,  -7, -92,  23, -72, -10, -69, -87, -80,  25,  51,  15, -77, -65, -70, -81, -94, -84; D=-8;
/I:         I=-8; DM=-21;
/M: SY='E';  M= -62, -75,   1,  52, -70, -18,  24,  -6,  18,   6, -58,  48, -67,  10,  26, -55,   1, -64, -81, -64;
/M: SY='L';  M=   8, -72,   4,  31,   6, -70, -60,  22, -13,  41, -48,  30, -72, -57, -64,  -2, -57, -50, -71,  11;
/M: SY='P';  M= -58, -74,  -3,  20,  -4, -62,  24, -75,  31, -76, -67,  50,  53,  19, -52,  43,  -9, -73, -80, -64;
/M: SY='Q';  M= -10, -70, -66, -64, -53, -71, -61,  18, -60,  28, -46,  31, -74,  34,  -5,  -3,  23,  30, -71,  34;
/M: SY='C';  M=   9,  60,   6,  28, -74,  -9,  22, -15, -55, -70, -64,  10,  36, -55,  17,  16,   4, -13, -84, -69;
/M: SY='E';  M= -18, -74,  10,  69, -77, -67, -55, -68, -45, -71, -65,  29, -64,  38,  24,  20,  -4,   8, -82, -68;
/M: SY='A';  M=  45, -71,  -1,  22,   0, -64, -62,  17, -58, -61, -58, -59,  12,  42, -62,  16,   2,  -6, -72,  13;
/M: SY='W';  M= -63,  28,   4, -55, -63, -71,  19, -57,  19,  34, -52,  30,  11,  41,  19, -10, -59,  -9,  47, -59;
/M: SY='Q';  M=   6, -79,  28,  35, -79, -69, -53, -75, -38, -71,  10, -52, -67,  73,  69, -53,  -2, -71, -78, -65;
/M: SY='W';  M=  29, -72,  -3,  -4,  26, -71, -65, -47, -57, -14, -53, -66, -74,  34,  23, -59, -59,  48,  57,  19;
/M: SY='Y';  M= -62, -77,   1,  64, -54, -73,  25, -62, -52, -60,  49,   7, -67,  37, -56, -57,   4,  -9, -62,  71;
/M: SY='E';  M= -57, -75,  31,  55, -76,  10, -58,  -7,  29, -70, -65,   6, -64,  16,  -5,  17,  -4,  -8, -81, -68;
/M: SY='D';  M= -18, -76,  55,  45, -74, -10, -58, -13,  16,  -2, -63, -51, -66,  13,  24,  21, -56, -66, -81, -66;
/M: SY='F';  M= -62, -71, -69, -71,  73, -71, -63,  43, -64, -21, -51,  34, -75, -66,  -5,  33,  -3,  -9, -61,  12;
/M: SY='F';  M=   9, -72, -82, -76,  96, -78, -67,  34, -12,   7, -47, -73, -80, -76, -70, -68, -63, -46, -50,  20;
/M: SY='W';  M= -65, -80, -65,  -6,  28, -73,  30, -63,  14,  15, -55, -62,   3,  56,  35,  -7, -63, -66,  86,  16;
/M: SY='D';  M=  11, -71,  40,  20,   5, -64,  22, -58, -58, -19,  26,  32,  12, -55, -64,  29,  -9,  11, -81, -61;
/I:         I=-36; MD=-90;
/M: SY='H';  M= -10, -77,  25,  48, -77, -66,  86, -78, -53, -26, -64,   3, -67,  44, -56,  33, -57, -75, -88, -60; D=-36;
/I:         I=-36; MI=0; MD=-90; IM=0; DM=-90;
/M: SY='P';  M= -66, -82,   1,  35, -78, -72, -58, -77,  43, -19, -67,  34,  55, -48,  53, -60, -61, -75, -81, -71; D=-36;
/I:         I=-36; DM=-90;
/M: SY='Y';  M= -20, -75,   3,  -3, -57, -17, -60,  -8,  16,  19, -52, -61,   3,  17,  26,  -4, -58,  23, -69,  40;
/M: SY='F';  M= -68, -73,  -2, -71,  58, -81, -64, -42,  -4,  54, -42, -74, -81, -69, -68, -71, -63,  12,  58,  51;
/M: SY='R';  M= -58, -75,   7,  19,  -4, -12, -59,  -6,  20, -20,  23, -54,  12, -50,  50,  40,  -4, -62, -76, -62;
/M: SY='H';  M= -15, -75,  44,  -2, -71,   7,  68, -12,   0,  -5, -61,  11,  10, -53,   0,  18,  -6, -66, -84, -61;
/M: SY='C';  M=  24,  32,   3, -62,   5,  26, -64, -18,  -1,   0,  15,   1, -70, -59,  -3,  32,   4, -59, -76, -62;
/I:         I=-19; MD=-47;
/M: SY='D';  M= -23,  22,  37, -61,  25, -75,  31,  -4,  -8,  28,  29,   8,   1, -63,  -2, -66, -63, -58, -72,  20; D=-19;
/I:         I=-19; MD=-47;
/M: SY='Q';  M= -12, -79,  36,  44, -71, -74, -59, -64, -53,  29, -57, -58,   4,  63,   2, -59,  -2, -65, -81, -66; D=-19;
/I:         I=-19; MD=-47;
/M: SY='E';  M= -70, -88,  19,  55, -89, -81, -66, -83,  45, -83, -77, -61, -73,  13,  24, -12, -67, -14, -89, -77; D=-19;
/I:         I=-19; MD=-47;
/M: SY='N';  M=  23, -83, -67, -10, -81, -17, -71, -22, -12,   2, -69,  48,   2,  10, -71,  -5, -66, -72, -91, -79; D=-19;
/I:         I=-19; MD=-47;
/M: SY='R';  M= -18,-103, -82,  -7,   3, -95,  28, -99,  13, -93, -85, -79, -93,  35,  38, -81, -87, -96, -96, -78; D=-19;
/I:         I=-19; MI=0; MD=-47; IM=0; DM=-47;
/M: SY='I';  M=   8, -79, -83, -78, -69, -16, -82,  42, -77, -20,  16, -75, -81,  14, -80,  -6,   0,  37, -88, -71; D=-19;
/I:         I=-19; DM=-47;
/M: SY='G';  M= -55, -76,  27,   0, -79,  67, -67, -79,  20, -24, -71, -51, -68, -59, -63,  15,  23, -75, -81, -73; D=-19;
/I:         I=-19; DM=-47;
/M: SY='F';  M= -64, -73, -76,  -3,  43, -84, -73,  41, -69,  23,  24, -72, -76, -70,  -8, -66,  34,  28, -72, -52; D=-19;
/I:         I=-19; DM=-47;
/M: SY='P';  M=  10, -79,  -2,   0, -73,  11, -64,  15,  17, -71, -64, -59,  53,  37, -60,  20, -58, -64, -75,   9; D=-19;
/I:         I=-19; DM=-47;
/M: SY='K';  M=  24,  24, -57,  -4, -76, -62,  51, -71,  52, -74, -65,  11,  51, -51, -50,  32, -53, -23, -81, -66;
/M: SY='L';  M= -14, -69, -79, -74,  12, -80,  28,   4, -74,  73, -35, -75, -80, -69, -73, -11, -59,  16, -72, -51;
/M: SY='R';  M=   1, -76, -65,  -6,   6, -15, -57, -63, -40,   5, -56, -60, -74,   6,  84,  -3, -61, -16, -69,  14;
/M: SY='H';  M= -64, -79,  38,  47, -69, -74,  58, -64,  -8,  18, -56, -54, -68,  49,  41, -59, -62, -14, -81, -60;
/M: SY='W';  M=  45, -71,   5, -58,  27, -63, -59, -66,  25, -64, -61, -58, -70, -57,   0,  18,  17, -61,  59,  56;
/M: SY='L';  M=  11, -70, -73,  19, -49, -79, -70,  24, -70,  69, -36, -76, -76, -65, -72, -68, -60,  17, -74, -58;
/M: SY='E';  M=   7, -72,   7,  46, -73, -11, -57, -15,  -3, -21,  11,  31, -65,  16,  -2,  37,  -3, -63, -80, -67;
/M: SY='Q';  M= -58, -75,   9,  38, -78,  -8,  27, -76,  18, -33, -65,  57, -66,  67, -49,  28, -54, -74, -82, -65;
/M: SY='I';  M= -63,  33,   3,  15,  31,   9, -68,  40, -66,  30, -47, -66,   5,  29, -69, -64, -61,  -2, -72, -56;
/M: SY='W';  M= -63, -71, -78, -70,  31, -81, -71,  21, -70,  53, -40, -72, -77,  29, -70, -65,  26,  29,  57, -49;
/M: SY='W';  M= -15, -79, -60,  36,   7, -10,  50, -13, -54, -23, -61,   8, -70,   9,  21, -17, -10, -68, 114, -48;
/M: SY='K';  M=   8, -74,  45,  -2, -77, -63, -56, -16,  61, -73, -66,  32, -66,  16,   9,  10,  -3, -67, -81, -67;
/M: SY='R';  M= -61, -75,   4, -55, -64, -71,  46,  -4,  35,  18,  47, -55, -71, -49,  59,  31, -57, -59, -78, -58;
/M: SY='Y';  M= -66, -76,  -1,  -6, -41, -80, -57,  39,  -4,  32,  46, -69, -76, -60,  -4, -68, -61,  -2, -57,  77;
/M: SY='Q';  M= -22,  24, -58,   2,  29, -12, -57, -69,  31, -16, -60,  10, -69,  64,  24,  30, -56, -68, -71, -57;
/I:         I=-36; MD=-90;
/M: SY='E';  M= -66, -80,  30,  53, -77, -75, -61,  -7,  -7,  -3, -65,  31, -70,  36, -11, -59,  23, -67, -87, -71; D=-36;
/I:         I=-36; MI=0; MD=-90; IM=0; DM=-90;
/M: SY='S';  M=  10,  16, -58, -61, -67, -10, -60,  -5,  -1,  12, -58,  48, -69, -55,  -5,  60,   2, -58, -81, -66;
/M: SY='L';  M= -18,  32, -77, -13,  44, -81, -71,  37, -71,  46, -40, -74, -78,  13, -72, -68, -60,  33, -69, -50;
/M: SY='P';  M= -10, -87, -58,  36, -85, -68, -66, -75,  -3, -81, -70, -68, 114, -57, -66, -60, -59, -76, -79, -80;
/I:         E1=0; IE=-380; DE=-380;
» more

Post-processing [info]

COMPETES_HIT_WITH PS51705; PS51706; PS51709; PS51710; PS51711; PS51712; PS51713; PS51714; PS51715; PS51716; PS51717; PS51719; PS51720; PS51721; PS51722

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_06 which contains 572'619 sequence entries.


Total number of hits 130 in 130 different sequences
Number of true positive hits 130 in 130 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 2
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 98.48 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] DOMAIN
Feature description [info] Dynamin-type G
Version [info] 4

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
130 sequences

ARC5_ARATH  (Q84N64), BDLP_NOSP7  (B2IZD3), CRFC_ECOLI  (P0DM85), 
CRFC_ECOLX  (P0DM86), DLP1_CAMJJ  (A0A0H3PJL7), DLPA_DICDI  (Q55F94), 
DLPB_DICDI  (Q54MH8), DLPC_DICDI  (Q55AX0), DNM1L_BOVIN (Q2KIA5), 
DNM1L_CAEEL (Q8WQC9), DNM1L_DANRE (Q7SXN5), DNM1L_HUMAN (O00429), 
DNM1L_MOUSE (Q8K1M6), DNM1L_RAT   (O35303), DNM1_SCHPO  (Q09748), 
DNM1_YEAST  (P54861), DRP1A_ARATH (P42697), DRP1B_ARATH (Q84XF3), 
DRP1C_ARATH (Q8LF21), DRP1D_ARATH (Q8S3C9), DRP1E_ARATH (Q9FNX5), 
DRP2A_ARATH (Q9SE83), DRP2B_ARATH (Q9LQ55), DRP3A_ARATH (Q8S944), 
DRP3B_ARATH (Q8LFT2), DRP4A_ARATH (Q9ZP56), DRP4C_ARATH (Q9ZP55), 
DRP5A_ARATH (F4HPR5), DYN1_BOVIN  (Q08DF4), DYN1_CAEEL  (P39055), 
DYN1_HUMAN  (Q05193), DYN1_MOUSE  (P39053), DYN1_RAT(P21575), 
DYN2_BOVIN  (A6H7I5), DYN2_HUMAN  (P50570), DYN2_MOUSE  (P39054), 
DYN2_RAT(P39052), DYN3_HUMAN  (Q9UQ16), DYN3_MOUSE  (Q8BZ98), 
DYN3_RAT(Q08877), DYNA_DICDI  (Q94464), DYNB_DICDI  (Q9U1M9), 
DYN_DROME   (P27619), EHD1_ARATH  (Q94CF0), EHD1_BOVIN  (Q5E9R3), 
EHD1_HUMAN  (Q9H4M9), EHD1_MOUSE  (Q9WVK4), EHD1_PONAB  (Q5RBP4), 
EHD1_RAT(Q641Z6), EHD2_ARATH  (B3LF48), EHD2_HUMAN  (Q9NZN4), 
EHD2_MOUSE  (Q8BH64), EHD2_RAT(Q4V8H8), EHD3_HUMAN  (Q9NZN3), 
EHD3_MOUSE  (Q9QXY6), EHD3_RAT(Q8R491), EHD4_HUMAN  (Q9H223), 
EHD4_MOUSE  (Q9EQP2), FZO1_CAEEL  (Q23424), FZO1_SCHPO  (Q9USY7), 
FZO1_YEAST  (P38297), FZO_DROME   (O18412), FZO_DROSI   (Q9N6P4), 
MARF_DROME  (Q7YU24), MFN1_HUMAN  (Q8IWA4), MFN1_MOUSE  (Q811U4), 
MFN1_RAT(Q8R4Z9), MFN2_HUMAN  (O95140), MFN2_MOUSE  (Q80U63), 
MFN2_RAT(Q8R500), MGM1_CHATD  (G0SGC7), MGM1_YEAST  (P32266), 
MSP1_SCHPO  (P87320), MX1B_MOUSE  (P09922), MX1_BOVIN   (P79135), 
MX1_CANLF   (Q9N0Y3), MX1_EUMJU   (Q4ADG8), MX1_HORSE   (Q28379), 
MX1_HUMAN   (P20591), MX1_ICTPU   (Q7T2P0), MX1_MACMU   (A1E2I4), 
MX1_MOUSE   (Q3UD61), MX1_ONCMY   (Q91192), MX1_OTABY   (Q4ADG7), 
MX1_PHOVI   (Q4ADG6), MX1_PIG (P27594), MX1_PONAB   (Q5R5G3), 
MX1_RAT (P18588), MX1_SHEEP   (P33237), MX2_BOVIN   (Q9BDI7), 
MX2_BUBBU   (A0MWD1), MX2_CANLF   (Q9N0Y2), MX2_HUMAN   (P20592), 
MX2_ICTPU   (Q4U4N4), MX2_MACMU   (A1E2I5), MX2_MOUSE   (Q9WVP9), 
MX2_ONCMY   (Q91196), MX2_PIG (A7VK00), MX2_RAT (P18589), 
MX2_SHEEP   (Q5I2P5), MX3_ONCMY   (Q91197), MX3_RAT (P18590), 
MXA_DANRE   (Q8JH68), MXB_DANRE   (Q800G8), MXC_DANRE   (Q6DKF0), 
MXE_DANRE   (Q800G5), MX_ANAPL(P33238), MX_CHICK(Q90597), 
MX_CTEID(Q6TKS7), MX_DICLA(Q2KTC2), MX_EPICO(Q6PW23), 
MX_LARCR(Q000A9), MX_PERFL(P20593), MX_SINCH(Q6TN15), 
MX_SOLSE(Q5U752), OPA1_CHICK  (Q5F499), OPA1_DANRE  (Q5U3A7), 
OPA1_HUMAN  (O60313), OPA1_MOUSE  (P58281), OPA1_ONCMA  (O93248), 
OPA1_PONAB  (Q5RAM3), OPA1_RAT(Q2TA68), SDL5A_SOYBN (Q39828), 
SDLCA_SOYBN (Q39821), SRCA_CHICK  (Q90577), SRCA_HUMAN  (Q86TD4), 
SRCA_MOUSE  (Q7TQ48), SRCA_RABIT  (P13666), VPS1_SCHPO  (Q9URZ5), 
VPS1_YEAST  (P21576)
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UniProtKB/Swiss-Prot
False negative sequences
2 sequences

DLP2_CAMJJ  (A0A0H3PJK4), DYNA_BACSU  (P54159)

		
PDB
[Detailed view]
80 PDB

1JWY; 1JX2; 2AKA; 2J68; 2J69; 2QPT; 2W6D; 2X2E; 2X2F; 3L43; 3SNH; 3SZR; 3T34; 3T35; 3W6N; 3W6O; 3W6P; 3ZVR; 3ZYC; 3ZYS; 4BEJ; 4CID; 4H1U; 4H1V; 4P4S; 4P4T; 4P4U; 4UUD; 4UUK; 4WHJ; 5A3F; 5D3Q; 5GNR; 5GNS; 5GNT; 5GNU; 5GO4; 5GOE; 5GOF; 5GOM; 5GTM; 5MTV; 5MVF; 5OWV; 5OXF; 5UOT; 5WP9; 5YEW; 6DLU; 6DLV; 6JFK; 6JFL; 6JFM; 6JSJ; 6JTG; 6QL4; 6RZT; 6RZU; 6RZV; 6RZW; 6S9A; 7AX3; 7SOX; 8CT1; 8CT9; 8EEW; 8EF7; 8EFF; 8EFR; 8EFS; 8EFT; 8SXZ; 8SZ4; 8SZ7; 8SZ8; 8T0K; 8T0R; 8T1H; 8TYM; 8TYN
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