We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
ProRule PRU01060
View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU01060
General rule information
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| Accession | PRU01060 |
| Dates | 27-APR-2016 (Created)
22-NOV-2019 (Last updated, Version 4) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51723; PEPTIDASE_M60 |
Name | Peptidase family M60 domain |
| Function | The peptidase family M60 domain belongs to the zincin superfamily of zinc-requiring metalloproteases (clan MA, subclan MA(E)). The peptidase family M60 domain contains the metal-binding consensus motif HExxH. The peptidase family M60 domain targets complex host glycoproteins, such as mucins. |
| Scope(s) |
Eukaryota Bacteria Gammaproteobacteria Viruses Betabaculovirus |
| Example(s) | P29998; |
Propagated annotation
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Features
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| From: PS51723 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="Peptidase M60 #" | |||||||||
Additional information
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| Size range | 277-314 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Bacteria [5] Eukaryota [13] Viruses [3] All [ 21 ]
- Retrieve set of proteins with 3D structure for this domain