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Entry: PS51723

General information about the entry

Entry name [info] PEPTIDASE_M60
Accession [info] PS51723
Entry type [info] MATRIX
Date [info] 01-JUN-2014 CREATED;
01-JUN-2014 DATA UPDATE;
12-AUG-2020 INFO UPDATE.
PROSITE Doc. [info] PDOC51723
Associated ProRule [info] PRU01060

Name and characterization of the entry

Description [info] Peptidase family M60 domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=309;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=304;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.4184458; R2=0.0078857; TEXT='-LogE';
/CUT_OFF: LEVEL=0; SCORE=962; N_SCORE=10.0; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=518; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-28; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380;
...
                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-380; BD=-380;
/M: SY='H';  M= -24, -37,   2,   5, -67,   3,  81,-102,   3, -43, -45,  48, -12,  34,  -8,   8,   1, -40, -11, -30;
/M: SY='D';  M= -11, -50,  61,   1, -26,  18, -87, -10, -43, -26, -15,  39,   3, -23, -11,   1, -11, -58,-107,  19;
/M: SY='W';  M= -36, -38,   6, -66,  36, -40, -32, -45, -10, -26,   4, -16, -66, -89,  48, -66, -31, -48, 122,  49;
/M: SY='Q';  M= -91,-106, -88,  -7,  17, -76,  45,  -6, -18, -70,  -6,  23,-100,  85,   0, -27,  19,   3, -99,  32;
/M: SY='P';  M= -18, -56,  -8, -57, -24, -64,   9, -66, -89, -48, -42, -48,  89, -88, -27,  65,  -5, -44, -30, -43;
/M: SY='T';  M= -11, -44, -53, -94, -90,-100, -99,   1, -92,  27, -80, -84, -95, -94, -98, -22, 102, -40,-113, -93;
/M: SY='G';  M= -54,-106, -58,-101,-109,  97, -39,-112, -94,-111, -47, -30,   4, -94,  -6, -26, -36, -40,-105, -48;
/M: SY='Y';  M= -24,  -9, -65,-104,  27, -73, -96,  42, -65,  48, -71,-104,-109, -53,  -6, -98, -24,  24,  15,  51;
/M: SY='Y';  M= -20,-108,-105, -70,  -2,-105, -43,  22, -98, -37, -38,-102,-108, -56, -98, -10, -41,  12,  98, 107;
/M: SY='A';  M=  58,   2,-107,-100, -36, -36,-102,   4, -74,  45, -33,-101,-105, -47,-102, -88, -55,  43, -24, -47;
/M: SY='P';  M=   9,-106, -26,   4, -23, -61, -42, -48,  13,  -9, -33,  20,  77,  11,  12,  -7,  -5, -37,-107, -97;
/M: SY='P';  M=  59,-104, -60,  -4,-110, -46, -33,-100,  19,-104, -95, -91,  88,   3, -48, -27, -26, -47,-108,-103;
/M: SY='G';  M= -50,-105, -32, -69,-111,  93, -12,-116, -44, -87,-102,  50, -99, -13, -22, -42, -93,-111,-107,-104;
/M: SY='E';  M= -11, -38,  48,  65,-105, -70, -87, -46,   9, -99, -24, -81, -93,  44, -27,   6,  15,   3,-111, -27;
/M: SY='T';  M= -54, -34, -26,  37, -96, -51, -21,  -8,  -3,   1, -18,  -6,  14,   2,   5,  15,  42,  22, -36, -94;
/M: SY='I';  M=  -1,-100,-112,-107,   5, -37,-107,  69,-105,  30,  14,-104,-106,-102,-106, -40, -63,  53,-104, -85;
/M: SY='T';  M= -70, -31, -40,  28, -44, -71, -15,  12,   5, -41, -87, -39, -95, -26,  24,   6,  76,   3,-110, -27;
/M: SY='I';  M= -53,   0,-114,-109, -32,-115,-110,  71,-106,  26, -35,-108,-108,-105,-108,-100, -53,  68,   9, -26;
/M: SY='R';  M= -58,-104,   1,  28,   4,-100, -22, -22,  11, -40, -40,  -5, -98, -14,  49,  10,  47, -42, -15,  38;
/M: SY='V';  M=   2, -13,-104, -97,  15, -34,-100,  26, -94,  12, -14, -98,-105,  30,   5, -15,  -9,  59,-103, -15;
/I:         I=-14; MI=0; MD=-34; IM=0; DM=-34;
/M: SY='E';  M= -32,-120, -41,  15,-117,  10, -38, -60, -18,  -7,-107,  10,  11,-102, -75,   7,   6, -56, -16,-114; D=-14;
/I:         I=-14; DM=-34;
/M: SY='D';  M= -32, -33,  49,  28, -64, -19, -39, -26, -17, -47, -46,  16,  11, -49, -62,  25, -13, -52,-121, -52; D=-14;
/I:         I=-14; DM=-34;
/M: SY='N';  M=  -7,-106,  34,  -5, -22,   0, -93, -14, -19, -47, -42,  44,  11,   4, -48,  18,  15, -20,-115, -58; D=-14;
/I:         I=-14; DM=-34;
/M: SY='N';  M=  11, -53,   0, -17,  -1,  14,  27,  -9,  -9, -40, -48,  39, -12,   1, -14,  17,  16,   0,-107, -27;
/M: SY='P';  M= -26,-105,  28,  -2, -58,  23, -44, -68,   8, -64, -15,  33,  48,   3, -90, -13,  27,  -5,  12,  13;
/M: SY='Q';  M=  20,  -7,   6,  -2, -64,   8,   1, -49, -11, -50,  -9,  12,  27,  35,  -9,   0,  21,  -3, -16, -21;
/M: SY='N';  M= -24, -15,  25,  -7,-104,  22, -24, -44,  23, -32, -40,  52,  16, -19, -26,   8,  32, -33, -30, -98;
/M: SY='W';  M= -56,  20,-107, -64,  10,-109, -39,  46, -70,  35, -75,-102,  33, -17, -32, -28,   0,  29,  65, -24;
/M: SY='T';  M= -32,-102, -66,  -4, -10, -10,   1, -23,  34, -15, -21, -23, -54,  33,  28,  18,  40,  -3,-105, -23;
/M: SY='V';  M=  -9,   3, -72, -71, -25, -42,-106,  56,-102,  38, -70,-104, -32,-101, -42, -48, -38,  58,-106, -28;
/M: SY='Q';  M=   8,  11, -58, -59,  -8, -55,   6,  -6,  -4,  -7, -84, -26,   7,  69,  35, -43, -35,   2,  13,  27;
/M: SY='I';  M= -54, -35, -61,-106,  11, -56,-105,  73,-103,  40,   1, -25,-106,-101, -61, -44,  -2,  31,-103, -84;
/M: SY='G';  M= -40,-102, -59, -64,-101,  68, -19, -63, -56, -13, -39,  61,-100,  19, -43,  -5,  10,  -8, -27, -52;
/I:         I=-25; MD=-63;
/M: SY='C';  M=  13,  81,  -4, -96, -39, -61,  -4, -47, -22,  -5, -14,  17, -43, -15, -18, -14,  30,   0,-113,  -2; D=-25;
/I:         I=-25; MD=-63;
/M: SY='H';  M=-102,  14,   8, -20, -69,-108, 105, -47, -43, -16, -35, -19,  -1,  29,  16, -44, -99, -60,-119,   3; D=-25;
/I:         I=-25; MD=-63;
/M: SY='T';  M= -26,-109, -27, -46,   3, -12, -12, -42, -20,  -1, -95,  15, -12, -28,  12,  13,  44, -40,-115, -50; D=-25;
/I:         I=-25; MI=0; MD=-63; IM=0; DM=-63;
/M: SY='D';  M= -15,-111,  67,   8, -68, -43, -14,-101, -21,   8, -97,  -7,  28, -25, -21, -30,   5, -49,   4, -61; D=-25;
/I:         I=-25; DM=-63;
/M: SY='N';  M= -57, -50,  60,  -7,-106,  27, -28, -49, -59, -78,-100,  77, -60,  -7, -33,  39, -57, -58,-116, -31;
/M: SY='N';  M=  -5,-101, -12, -51,  21,  -3, -21, -12, -24,  29, -82,  39,  -3, -27,   4,   8,  13, -21,-102,   1;
/M: SY='D';  M=   8, -41,  46,  10, -69, -23,  34, -94, -85, -28, -53,  41, -13, -21, -11,  19,  30,   3,   0, -57;
/M: SY='N';  M= -47,-104,  26, -10, -63,  11,  21,-105,  35, -63, -96,  38, -29,  19,  35,  35,   3, -66,-110, -33;
/M: SY='H';  M=  -1, -35, -41,  30, -12, -24,  54, -18,   8, -23,  12,  -2,   5,  37, -17, -10,  -9, -24,  34,  11;
/M: SY='W';  M= -42,-104,  28,  26,  -9,   5,   2, -27, -22, -46, -24,  32, -25,  -4,   6,  12,  38, -52,  38,  10;
/I:         I=-15; MI=0; MD=-37; IM=0; DM=-37;
/M: SY='P';  M= -55, -12, -25, -14,-132, -46, -13,-127,  -7, -38,-122, -14,  36, -36,-118,  -4, -30, -61,-140, -67; D=-15;
/I:         I=-15; DM=-37;
/M: SY='W';  M= -78,-137,-130, -30, -42, -83, -53, -31, -53,  -4, -20, -14, -67,-121, -65, -73,  -6, -73, 101, -17; D=-15;
/I:         I=-15; DM=-37;
/M: SY='K';  M= -57,-131, -17, -79,-117, -59,-111, -34,  32, -52,-115,  11, -39, -13,  -3, -31, -50, -47,-124,  25; D=-15;
/I:         I=-15; DM=-37;
/M: SY='R';  M=-116,-131,-111,-108,-128, -60,-106,-129, -61,-127, -55,  26,-127, -98,  82, -16, -45, -59,-133,-118; D=-15;
/I:         I=-15; DM=-37;
/M: SY='W';  M= -30,-131,-127,-118, -37, -43, -24, -49,-111,  -9,  16, -57,  16, -38,  10, -81, -68, -37,  98,   0; D=-15;
/I:         I=-15; DM=-37;
/M: SY='P';  M= -64,-134,-113, -37,-132, -36, -48,-123,  -6, -97,-118, -68,  95,-110, -76, -25, -49, -79,-129,-127; D=-15;
/I:         I=-15; DM=-37;
/M: SY='R';  M= -50,-119, -71, -44,-107, -60, -36,  -6,   4,  -3, -36,  13,-119, -22,  18,  -5, -16,   5,-122,  -8; D=-15;
/I:         I=-15; DM=-37;
/M: SY='V';  M= -72,-117, -32, -20, -13, -21, -45,  11, -71,   7,  27, -63, -61, -36,-115, -76,   2,  30,-118,   0; D=-15;
/I:         I=-15; DM=-37;
/M: SY='S';  M= -19, -52, -59,  28, -94, -47,   0,  -5,   9,   5, -15, -23,   6,  -3,   5,  34,  25,  12,-107, -11;
/M: SY='K';  M=  -8,  34, -23, -31, -97, -56,   7,  -3,  40, -65,  -2,  26, -41,  28,  20,   8,  30, -22, -13,   6;
/M: SY='S';  M= -16, -49, -35,  14, -36,  -6, -92, -49, -28, -97, -92, -82, -24,  17,  11,  59,  53,   9, -30, -16;
/M: SY='F';  M= -73,-105,-100, -14,  58, -72, -45,  29,  -6,  -8,  -3, -12,  14,   9, -21, -39,  -8,  17,  20,  48;
/M: SY='P';  M=  -4,-103,  29,   2,-103, -70, -26, -36,   1, -65,  -3,  44,  49,  24, -18,   3,  38, -10,-112, -52;
/I:         I=-19; MD=-49;
/M: SY='L';  M= -74,-105, -72,-110, -35, -79, -42,  43,-110,  66,   3,-112, -42,-105,-110, -69, -94,  30, -22, -26; D=-19;
/I:         I=-19; MD=-49;
/M: SY='D';  M= -49,-124,  26, -46, -54, -45, -51, -13,  19, -35,-109,  -2,  -9,-105, -10, -42,   2, -25,-127, -15; D=-19;
/I:         I=-19; MI=0; MD=-49; IM=0; DM=-49;
/M: SY='N';  M=   4, -52, -68, -37, -45, -17, -23, -50,   4,-115,-109,  35,   0, -24, -68,  18,  29, -44,-125, -59; D=-19;
/I:         I=-19; DM=-49;
/M: SY='N';  M= -60,-103,  -2,  23, -43,  19, -32,-103,  -3, -80, -40,  61,  23,  27,   3,  31,  17, -56,-110, -53;
/M: SY='G';  M= -18,-104,  14,  18,-108,  56, -90,-107,  20, -66, -98,  18, -49,  26,  -7,  30,  -6, -55, -19, -99;
/M: SY='W';  M= -24, -51,  -2,  28, -47, -67, -22,  -3,  10, -48, -22,   6,  -1,  20, -11,   1,  27,  21,  79, -18;
/M: SY='N';  M= -41, -99, -86, -61,  11, -26,  20,   8, -19, -17,  -6,  75, -40,  10, -92, -56,  48,  17,-108, -25;
/M: SY='T';  M= -67,-101, -27,  33, -28, -43, -91,   5,  47, -61, -47, -36, -54,   4, -17,  35,  58, -19,-108, -49;
/M: SY='I';  M= -74,-102,-109, -47,  50,-112, -26,  61, -49,  25,   7,-103, -54,-101,-103, -36, -11,  35, -13,  29;
/M: SY='T';  M=  11,  12,  -3, -35, -18,   9, -48, -32,   2, -75, -45, -23, -97, -21,  -4,  42,  51,  11, -31, -30;
/M: SY='S';  M=  25, -54,  -9, -92,  15, -57,  12, -20, -91, -91, -41,  27, -99, -89, -60,  61,  25,  25,  37, -27;
/M: SY='P';  M= -13,-108, -10,  29, -73, -41, -15, -45, -25, -32, -94,   6,  90,  -1, -20,  13,   8, -72,-109, -30;
/M: SY='Y';  M= -47, -47, -17, -18,  35, -79,  58, -18, -10, -26, -43,   9, -59,  19,   3, -47,  -5, -21,  40,  80;
/M: SY='G';  M= -31, -37,  30, -32,-108,  85, -97, -72, -45, -66,-100, -48, -21, -33, -43, -27,  -1, -19,   7,-102;
/M: SY='G';  M= -15,   4, -94,-103,-107,  97, -99,-114, -98, -69,-102, -81, -98, -95,-104,  15, -34,-107,-103, -13;
/M: SY='V';  M= -14, -51,-103, -61, -84, -39, -99,  16, -98,  42,  43,  -8,   7, -28, -44,   0, -12,  51,-107, -41;
/M: SY='I';  M= -41,-103,-111,-104, -81, -80,-106,  62,-104,  47, -15,-107,  45,-102,-107, -99, -40,  49,-107, -90;
/M: SY='Y';  M= -67,-108, -40, -49,  70, -59,  -5, -42, -96, -40, -33, -56,-110,   5, -95, -70, -44, -66,  15, 113;
/M: SY='I';  M= -52,-101,-114,-109,  42,-115,-107,  65,-107,  41, -27, -62,-109,-105,-107,-101, -54,  55,-100, -80;
/M: SY='R';  M= -26,-105,  31,  20, -40,  -3,  -9,   5,  -6, -45,  34,   7, -55,  11,  36, -13,  10, -14,   1,   8;
/M: SY='Y';  M= -59,  53, -68, -97,  17, -44,  -6, -33, -39, -16, -11,  32,  -3, -92, -12,  11,  29,  11,  40,  66;
/I:         I=-21; MD=-53;
/M: SY='P';  M= -34,-109, -24, -70, -29, -15,  -3, -12, -47, -22, -23,   0,  69,  -4, -43,   0,  27,   8,  15, -16; D=-21;
/I:         I=-21; MI=0; MD=-53; IM=0; DM=-53;
/M: SY='D';  M= -79,-112,  57,  -1, -45,   7, -28, -26, -23, -29,-101,  37, -68,  -1, -18,   0, -11, -29,-118,  -9; D=-21;
/I:         I=-21; DM=-53;
/M: SY='D';  M=  -4,-108,  32,  17, -59,  10, -92, -68,  -5, -81,-101,  29, -16,   0, -31,  20,  19, -37, -15,  12; D=-21;
/I:         I=-21; DM=-53;
/M: SY='Q';  M= -15, -29,  22,  30, -25,  -3, -53,-100,   1, -48, -95,   2,   8,  38,   1,  32,  37, -42, -22, -62;
/M: SY='N';  M=  -5,-103,  27,  13,  -3,  15, -35, -32,  -4, -74, -56,  47,  36,   6, -22,  17,   2, -23,-109, -95;
/M: SY='Q';  M=  32,-101,  -4, -12, -58,  -6,  -4,  -6, -25, -14, -36, -22,  11,  37, -15,  13,  37, -27,  12, -34;
/M: SY='P';  M=  12, -20, -34,   1, -60,  37, -16, -95,  -4, -37,   0,  29,  40,  24, -61,   8, -18,   0,-107, -12;
/I:         I=-33; MI=0; MD=-84; IM=0; DM=-84;
/M: SY='P';  M= -14,-104,  26,  17,   5, -12,  -1, -26,   9, -99, -94,  17,  33,  13,   9,  26,  21, -19,-109, -93;
/M: SY='V';  M= -21,-100,-111,-106,  29,-111,-109,  56, -78,   6, -35, -61,  -8,-104,-106, -73, -27,  73, -16, -84;
/M: SY='E';  M= -65,-104,  25,  51, -24, -34,  37, -57,  34,-100, -16,  11, -10,   5,  -4,  -7,  42, -32,-110, -49;
/M: SY='V';  M= -19, -37,-111,-107,  23,-111,-102,  53,-104,   7,  10, -59,-108,-103,-105, -97, -41,  69, -31,  41;
/M: SY='T';  M= -88,-102, -15,  36, -40, -98,  28, -42,  24, -61, -92,  12, -32, -12,  33,  18,  62, -23, -28, -27;
/M: SY='F';  M= -31,-101,-113,-109,  68,-113,-105,  65,-106,  15, -35,-106,-108,-106,-107, -99, -27,  48, -93,  -2;
/M: SY='S';  M= -13, -13,   4,  39,-103,   4, -90, -76, -12, -36, -19,  -2, -21, -21, -22,  59,  35, -16,-112, -98;
/M: SY='G';  M= -51,-103,   7, -19,-108,  75,   0,-111, -55,-111,-101,  65, -53, -16, -59,   8,   8,-107,-111, -50;
/I:         I=-31; MI=0; MD=-79; IM=0; DM=-79;
/M: SY='A';  M=  48,   3, -65, -98,  -2,  48,  12, -23, -50, -45, -45, -91,-102, -95, -28, -28, -30,  40,-102,  11;
/M: SY='V';  M=  -1,  -8, -94,   7, -50,  -9, -18,  31,  17, -30, -45, -34, -56,   8, -34,   0,  22,  36, -23,  19;
/M: SY='P';  M= -23,-107,   0,  14,-101, -76,   9, -33,  32, -17, -88, -16,  53,  32,  33, -39,   1,  16,-109, -48;
/M: SY='H';  M=  35, -51, -96, -95,  -1, -72,  60,   0, -94,  31,  28,  26,-103, -14, -95,   8, -18, -16,-101,  31;
/M: SY='P';  M= -55,-117, -64, -57,-112,   3, -15,-101, -93, -63, -98, -50, 122, -95,-104, -32, -63, -45,-109,-109;
/M: SY='Y';  M= -54, -50, -53, -73,  37,-107,  47,  -9, -67,  17,   7, -32, -61, -48,  15, -43,   2,  32, -16,  70;
/M: SY='F';  M= -14, -23,-110,-107,  90,-108, -31,   8,-103,  -4, -25,-104, -29,-104,-102, -64, -59, -34,  53,  79;
/M: SY='D';  M= -65, -47,  50, -26, -96,-102, -37,  40,  16, -66,   9,  29,-100, -17,  38, -43,   6,  27,  -4, -93;
/I:         I=-9; MD=-23;
/M: SY='H';  M= -53,-110, -47, -50,  10, -79,  44, -24, -20,  42,  13, -32,-113,   1, -63,  13, -62, -24,-103,  37; D=-9;
/I:         I=-9; MI=0; MD=-23; IM=0; DM=-23;
/M: SY='G';  M= -26, -22,   4,-102, -63,  70,-103,-121, -13, -93,-111,  30,-108, -12, -33, -56,   5,-115,-119,-112; D=-9;
/I:         I=-9; DM=-23;
/M: SY='K';  M= -14, -44, -22,  18, -60,   3, -17, -38,  29,-102, -40, -12,  10,  11,  -3,  -1,  -5,  16,-113, -16; D=-9;
/I:         I=-9; DM=-23;
/M: SY='T';  M= -34, -38,  15,   9,-106,   4,  42, -72, -21, -50, -44,  33, -99,   2,  -7,   1,  64, -49,-119, -98; D=-9;
/I:         I=-9; DM=-23;
/M: SY='T';  M=   2,-100,  46, -54,-106, -39, -18, -49,  -5,-103, -97,  19, -19,   6, -62,  44,  67, -71,-117, -98; D=-9;
/I:         I=-9; DM=-23;
/M: SY='D';  M=  -3,-105,  50,  27,-101, -73, -44,  10, -11, -16, -89,  45,  29,  35, -29, -85, -21,  10,-113, -97;
/M: SY='Q';  M=  20,-103,  33,  48, -68,  -8,  -6, -80,  -8, -61, -96,  24, -17,  51, -85,  15,  14, -67,-110, -46;
/M: SY='D';  M=   6,-105,  63,  51,-107, -52, -45, -33, -11, -62,   7,  21, -50,  31, -17,  14, -13, -55, -33, -97;
/M: SY='W';  M=-103,-116,-123,-110,  72,-107,-110, -34,-103, -47, -90,-116,-111,-105,-105, -70,-105, -17, 158,  36;
/M: SY='K';  M= -19,-104, -27,   9,  22, -45, -45,  -5,  49,   4,  -3,  15,  -3,  37, -11, -32, -15,  -6, -11, -87;
/M: SY='N';  M=   9,-103,   9,  48, -44, -73, -38,-103,  18, -61, -95,  55, -95,  38,  10,  16,   8, -75,-108, -15;
/I:         I=-22; MD=-55;
/M: SY='M';  M=  -5,-109,  11,  28, -68, -34, -18, -22, -50, -15,  65,  -4,-103,  45,  -4,   4,  -7, -48,-113, -52; D=-22;
/I:         I=-22; MI=0; MD=-55; IM=0; DM=-55;
/M: SY='W';  M= -26,-111,-108, -11, -89, -75,-106,  22, -24,  35, -16, -46, -11,  -5,-104, -98,  32, -14,  82, -11; D=-22;
/I:         I=-22; DM=-55;
/M: SY='R';  M=  -7, -35,  29,  -6,-104, -51,  -8, -48,  37, -21, -94,  22,-101,  26,  57,  -5, -64, -43,   9, -38; D=-22;
/I:         I=-22; DM=-55;
/M: SY='N';  M=  16,-104,  34,  -6, -40, -52, -14,-102,  28, -36, -95,  59, -37,  22, -29,   4,   1, -71, -28,  18; D=-22;
/I:         I=-22; DM=-55;
/M: SY='T';  M=  26, -19,   6, -19, -13, -15, -30, -45,  -7, -36, -92,  21, -52,   1, -24,  34,  41, -92,-101,  41; D=-22;
/I:         I=-22; DM=-55;
/M: SY='P';  M= -55,-106,  31,   2,-104, -11, -92, -43,  11, -56,   7,   1,  68,  33, -43,  -3,  23,  13,-111, -55;
/M: SY='A';  M=  46, -33,  -6, -58, -22,  11, -11, -25, -67,   2, -37, -30, -38, -15, -97,  35, -19,  25,-105,  -3;
/M: SY='P';  M= -23,-111,  -6,   7,-109,  11, -94,-102, -15, -25, -97,  21, 103, -89, -69,   0, -52, -73,-110,-106;
/M: SY='W';  M= -56, -10, -44, -65,  54, -67,   0,  -9, -99,  -8, -36,-105,-109, -13, -65, -23, -46,  -3, 133,  58;
/M: SY='A';  M=  68,  15,-100, -60,   3,  22, -39, -31, -96, -27, -16, -92,-100, -95,-101, -41,  23,  32,-106, -93;
/I:         I=-38; MI=0; MD=-97; IM=0; DM=-97;
/M: SY='E';  M= -68, -40,  48,  84,  19, -71, -31, -68, -83,  11, -25, -28, -95, -49, -90, -50, -62, -14, -23,  -9;
/M: SY='I';  M= -69,-101,-113,-107, -12,-115, -21,  62,-106,  56,  25,-108, -55, -60,-106,-102, -89,  46,-103, -24;
/M: SY='E';  M=  -4,  -2,  34,  47,  -2, -81,  -1, -50,  12, -48, -17, -19, -98,   4,  20,  -7, -33,  29,-107,  -8;
/M: SY='G';  M= -16,  -2,  -5, -94, -29,  60, -95, -63, -93,  -8,  -5, -10, -97, -91, -99,  42,  58, -92,-108, -54;
/M: SY='D';  M= -38,-108,  61,  44,-110,  32, -52,-111,  35, -82,-101,  -2,  27, -18,   6, -32, -27,-106,-111, -45;
/M: SY='H';  M= -46, -38, -57, -86, -44, -12,  68,-100,  30, -59, -90,  58, -53,  -1,  47, -22, -13, -24, -27,  51;
/M: SY='I';  M=  21, -45, -59,-103,  40, -76,-103,  54,-101, -10,  33, -33,-104,-100,-103, -12,  14,  48,-102, -83;
/M: SY='I';  M= -22, -36, -97,   2, -39,-106,  19,  64, -29,  -8,  15, -17,-101,  38,  -1, -36,   2,  28,-107, -53;
/M: SY='F';  M= -59, -31,-112,-107,  56,-113, -10,  49,-104,  41,  47,-105,-109, -49,-104,-100, -18,  28, -19,  14;
/M: SY='T';  M= -14, -43, -64, -94, -15,-100,  42, -17, -92,  29, -19,  21, -99, -57, -65, -13,  78,   5,-109,  -9;
/M: SY='V';  M=  10, -97,-108,-103,  19, -23,-101, -13,-101,  30,  53,-101,-105, -99,-102, -20,   7,  65,-104, -28;
/M: SY='P';  M= -65,-112, -92, -11, -63, -98,  -5, -99, -21, -27, -44, -60, 109,  -9,   7,  -4,  15,-101,-107, -26;
/M: SY='S';  M=  31, -99, -91, -34, -39, -92, -46, -48,  17, -47,  -6, -34,  16,   2,  24,  48,  40,  -7,-106, -18;
/M: SY='E';  M=  14,-103,  34,  37, -61, -39,  -9, -20,  26, -79, -94,  24, -53,  19,  -1,  14,  20, -20,-111, -57;
/M: SY='D';  M=  -2,-103,  57,   6, -24, -40,  -5, -31,  12, -42, -44,  37, -69,   4,   4,  20,  -6, -16,-108,  11;
/M: SY='M';  M=  32, -15,-104, -97,   5, -38, -98,  28,  21,  24,  41, -97,-103, -92, -11, -27, -31,  29,-101,  -6;
/M: SY='R';  M= -21,-106,  -3, -10, -96, -60, -87, -33,  36,  21, -86,  17,   8,  20,  66, -88, -10, -63, -21, -16;
/M: SY='K';  M=   8,-103,  18,  19, -40, -28,   7, -57,  46, -25, -28,  30, -59,  37,  -1,  -3,  -1, -23,-108, -34;
/I:         I=-13; MD=-32;
/M: SY='Y';  M= -20,-104, -64,-102,  18, -18,  22,  17,-101,  36, -11, -99,-108, -17, -69,  11,  -2,  16, -12,  45; D=-13;
/I:         I=-13; MD=-32;
/M: SY='I';  M=  10, -24, -42, -68, -61, -37,-108,  25, -20,  -3,  -6,  12, -69, -57,   1, -26,   5, -51,-119, -11; D=-13;
/I:         I=-13; MI=0; MD=-32; IM=0; DM=-32;
/M: SY='N';  M=  21, -15,  14, -37, -20,  10, -42,-114, -14,-115, -37,  23,  -4,  -7, -63,  -7, -61, -46,  12, -18; D=-13;
/I:         I=-13; DM=-32;
/M: SY='T';  M= -14,-106,  26,  33, -57,  -6, -35, -65,  15, -40, -36, -34,  -1,  12, -60,  18,  34, -11, -28, -11; D=-13;
/I:         I=-13; DM=-32;
/M: SY='D';  M= -53, -45,  86,  -6, -44,  -4, -20, -64, -17, -57, -40,  53, -98, -27,  11,   8, -18,-104, -26, -49;
/M: SY='P';  M=   2,-105,-104, -96, -16, -17, -41,  41, -98,  32,  23,-101,  71,  14,-102, -65, -54,  13,-104, -91;
/M: SY='D';  M= -30,-104,  51,  44, -57, -20, -43, -62, -12, -26, -93,  35, -30,  39, -60,   4,  14,  -5,-109,   1;
/M: SY='K';  M=  22,-104,  33,  33, -26, -36, -38, -78,  40, -62, -17,  -1,   8,  35, -10,   7, -15, -68, -13, -25;
/M: SY='L';  M= -34, -99,-107,-103,  25, -33,-100,  22,-102,  58,  23, -52,-106, -41,-103,  -3,  15,  31,-101, -45;
/M: SY='M';  M=  10, -15, -29, -34,  -9, -28,  -3,  34, -98,  43,  70,   0,-104, -94, -59, -24, -29, -10, -10, -25;
/M: SY='D';  M=  17,-104,  50,  40,-106, -15, -14,-104,  22, -30, -96,  33, -96,   5,  31, -27,  -3, -76,-111, -57;
/M: SY='Y';  M=   8,-104, -26,   6,  54,-102,  25, -23,   9,   4,  -5, -56,-103,  22, -30, -16,  -7, -62,   7,  62;
/M: SY='W';  M= -71,-112,-109,-104,  13, -70,  22,  -5, -99,   0,  -3, -57,-109, -96, -99, -30, -37, -23, 130,  93;
/M: SY='D';  M= -48, -34,  89,  23,-108, -40, -11, -71, -13, -18, -99,  49, -97,   1, -14, -23,  -4,-103,-120, -98;
/M: SY='N';  M= -60,-104,  31,  39, -67, -31,  -3, -66,  36, -41, -96,  39, -96,  18,  34,  28,  12,-100,-111, -96;
/M: SY='I';  M=   4,-101, -69, -74,   1, -80,-102,  60,-102,  23,  41, -37,-106, -52, -62, -47, -87,  53,-102,   4;
/M: SY='I';  M= -41,-101, -60,-104,  26, -75, -17,  58,-101,  -5,  58,-100,-105,-100, -41, -19,  11,  53,-102,  -9;
/M: SY='E';  M=  17, -57,  28,  43, -35,  -6,   4,  -5,   7, -99, -94, -26, -96,   0,  31,  13,  -3, -56,   3,  -1;
/M: SY='H';  M=  25, -14,  -7, -10,  19, -45,  32,  16, -48,   9,   1,   5, -46, -53,  -8,   4,   0, -18,  11,  19;
/M: SY='Y';  M= -37, -51,  -1,  21, -12, -32,  37,  -6, -91, -13,  26, -27,-103,  25, -92, -26, -14,   5, -87,  88;
/M: SY='D';  M=   7, -22,  61,   4, -19, -95,  35, -43, -29, -21, -12,  52, -32,  19, -57, -43, -57, -60,  13,  42;
/I:         I=-25; MI=0; MD=-63; IM=0; DM=-63;
/M: SY='E';  M=   5,-105,  49,  51,-102, -31,   2, -69,  21, -59, -34,  20, -95,  25, -24,  12, -14, -77,   4,   9;
/M: SY='L';  M= -69,-102, -64, -72,  37,-112, -13,  37,-103,  55,   8, -53,-109, -61,-103, -52, -19,  25, -16,  42;
/M: SY='M';  M=  45, -35, -39, -65, -51, -54, -91,  -5, -18,   0,  49,  13,-100, -48,   0,  33,  10, -37,  14,  21;
/M: SY='G';  M=  -2, -45, -40, -46, -44,  93, -97,-113, -95,-111,-102,   9, -54, -13, -70, -11, -46, -70,-105,-104;
/M: SY='L';  M= -65,-102, -39, -41,  39, -65, -94,  28, -54,  49,  26, -56,-107, -96, -10, -47,  15,  -1, -24,  45;
/M: SY='D';  M= -30,-104,  67, -13, -44, -51, -32, -51,   9, -82, -44,  15,  35, -12, -26,  34,  30, -29,-113, -18;
/M: SY='W';  M= -45,-105,  20,  -3,  27,  24, -11,  11,  13, -36,  -6,  12,  -5, -53,   7,   0, -15, -18,  28,   6;
/M: SY='P';  M= -22, -45,  20,  15, -98, -34, -43, -51,   1, -78, -15,  32,  35,   7,  13,  29,  18, -16,-105,  30;
/M: SY='R';  M=  13,-104,  21, -12, -15,  21,   6, -33, -11, -70, -94,   0,  31, -25,  32,  24,   2, -40,-105,   1;
/M: SY='P';  M=   6, -35,  18,  15, -67, -27, -10, -23,  31, -75, -17, -10,  54,  13,  13, -12, -17, -26, -17,   9;
/I:         I=-13; MD=-32;
/M: SY='R';  M= -12,-106,  20, -28,  10, -11,   2, -13,  -3,  -5, -24,   7,  -9,  -9,  28, -30,  12,   1,-105,   9; D=-13;
/I:         I=-13; MD=-32;
/M: SY='P';  M= -22,-115,   3,   2, -16, -52,  44, -56,   0, -25, -98,  20,  61,  -4,  12, -24, -47, -48,-115, -46; D=-13;
/I:         I=-13; MD=-32;
/M: SY='E';  M=  -8, -45, -41,  19, -62, -45,   9, -35, -19, -31,-104, -35,  -2, -17,  -4,   8,  18, -24,  18,-107; D=-13;
/I:         I=-13; MD=-32;
/M: SY='D';  M= -27,-128,  46, -29,-126,-117,  12, -53,  -6,-122,  -2,  24,  13, -29, -24, -52,-108, -43,-136, -36; D=-13;
/I:         I=-13; MD=-32;
/M: SY='R';  M= -28,-130,  -9, -50, -16, -48,  -3, -40,   0, -69, -47, -21,  -2, -15,   5,  -3, -30, -45,-132,-116; D=-13;
/I:         I=-13; MD=-32;
/M: SY='P';  M= -15,-131, -25, -72,-127, -94,-122, -16, -26, -51,-117,  12,  23, -67, -37,  -7, -20, -24, -26, -65; D=-13;
/I:         I=-13; MI=0; MD=-32; IM=0; DM=-32;
/M: SY='M';  M= -42,-121, -30, -58,  -7,-119,  27, -14,   0,  -2,  47, -53, -29,  23,  28, -82, -48, -71, -28, -15; D=-13;
/I:         I=-13; DM=-32;
/M: SY='R';  M= -54,  25, -93, -92,  31, -53,  -6, -37, -58, -44, -13,  50,-107, -20,  74, -32, -63, -29,  58,  53;
/M: SY='F';  M= -67,  -8, -66, -68,  79, -74, -24,  45, -25,  -7,   8,-100, -28, -62,   4, -63,  -1,  11,   8,  13;
/M: SY='V';  M=   2,  15,   8, -68,  -8, -39, -10,   1, -24, -14,  32, -10,-103,  -7, -28,  -9, -12,  62,-108, -14;
/M: SY='F';  M=  11,  17, -60, -16,  51, -67, -92, -24,  38, -15,  19,   3, -20, -49, -42, -16,  -7,   2,  28,  32;
/M: SY='D';  M=  38,-103,  86, -41, -31, -42, -16, -47, -46, -61,   2, -52, -32,  13, -14, -57,   5,  -6,-114, -33;
/M: SY='D';  M= -35,-104,  57, -25, -94, -49, -22,  29, -15, -15, -84, -29, -21,   8,  28, -31,  -9,  42,-111, -24;
/M: SY='Q';  M=   1,-105,  14,  10, -37, -29,  31, -30,  17, -70,  37, -18, -63,  71, -40,  15, -21, -28,   3,  20;
/M: SY='I';  M=  -4,-101, -56, -64,  -6, -30,  -5,  44, -36,  -6,  22,  34,   1,  -6, -38,  20,   6,  18, -33, -26;
/M: SY='S';  M= -10,-103,   9, -11, -11,  45, -93, -33, -15, -19, -93, -52,  21, -13, -26,  47, -14, -31,   6,   1;
/M: SY='H';  M=  30,  -4,  18, -89,   0,  30,  35, -19, -13, -60, -92,  -2,  35, -90, -28,  14,  -5, -16,  -5, -21;
/M: SY='G';  M=  15, -14,  -5, -60,-105,  85, -96, -45, -95, -66, -14,   9, -99, -93, -45,  -4, -49, -31, -26, -29;
/M: SY='W';  M=  25, -35, -66, -12,  30,  22, -92,  -1, -42, -20, -85, -38, -52, -94, -98, -47, -28,   3,  76,  75;
/M: SY='M';  M=  59,  -9, -60, -93, -35, -14,  11, -84, -42, -39, 103, -53,   4,  15, -93, -54, -52, -57,   2, -13;
/I:         I=-36; MD=-90;
/M: SY='H';  M= -77, -36, -43, -59,  29, -78, 101, -56, -58, -66,  16, -32,-108, -90, -92, -23, -40, -20,  14,  94; D=-36;
/I:         I=-36; MD=-90;
/M: SY='Y';  M=  46,  23,-115,-112, -55,-110, -44, -35, -69,-103,  23, -56,-119,-107, -40, -41, -27, -41,-103,  71; D=-36;
/I:         I=-36; MI=0; MD=-90; IM=0; DM=-90;
/M: SY='S';  M=  34,  -6, -28, -58, -45,  35, -94, -63, -91, -72, -94,   3, -50, -88, -97,  62,  41, -20, -21,  -7;
/M: SY='G';  M=  -2,-104,  35, -44,-105,  70,  26,-110, -66,-109,-100,  18, -13, -27, -20,  17, -10,-105,   5,  -3;
/M: SY='Y';  M= -28,-108,  -8, -26,  -7,   1, -17, -49, -63, -38, -86,  44,-106,  16, -28, -34, -62, -95,  41, 106;
/M: SY='W';  M= -74, -39, -57, -56,   5,  -4,  53, -66, -65, -59, -44, -32,  79,  -4,  23, -73, -49,-103,  97,  53;
/M: SY='I';  M=   5,  14,-104,-103, -64, -53,-103,  73, -99, -20,  39, -19, -56, -98,-104, -27,  46,  26,-108, -41;
/M: SY='M';  M=  46, -46, -59, -94, -37,  34, -35, -15, -91, -64,  73, -29,-100,  33, -22, -61, -10,  22, -28, -11;
/M: SY='C';  M=   8,  56, -71,  -6,  29, -13, -13,  26, -94, -13,  26,  14, -55,   0, -97, -17,  12, -30, -96,  48;
/M: SY='H';  M= -21,-102,   4, -15,  -4,  14,  48, -35, -90, -19, -91,  34,  46, -35, -62,  40,  20, -15,-111, -92;
/M: SY='S';  M=  -1,-101, -22, -32, -21,   8, -36,  11, -40,  -4,  -7,  29,   0,  -5, -22,  37,  28, -27, -16,  13;
/M: SY='D';  M= -22, -50,  65, -31, -28,  37, -46, -65, -21, -60, -51,  17,   3, -26, -49,  29,  15, -35,-109,  -1;
/I:         I=-29; MI=0; MD=-75; IM=0; DM=-75;
/M: SY='W';  M= -12,  46,  25, -42,  -4, -43, -94, -40, -42, -12, -38,  13, -58, -49, -44,  59,  24, -35,  80, -29;
/M: SY='M';  M=  23, -47, -46, -26, -33, -16,  26,  14, -37,   7,  44, -37,-100,  18, -62,  32, -12,  25,-107, -30;
/M: SY='S';  M=  15, -23,  21,   9,-104,  36, -89, -37,   2, -60, -97,  25,   7,  -7,  13,  37, -29, -98,-108, -17;
/M: SY='N';  M=  -4,   8,  10,  25,  25,   1,   8, -36, -12, -46,  20,  43,  -8, -49,   4,  18,  -1, -95,  -7, -24;
/M: SY='W';  M= -21, -40,-108,-103,  44, -72, -36,  32,-101,  33,  23, -42,  25, -51,-103, -65,   1,  16,  59,  31;
/M: SY='W';  M= -50,  -5,-109, -65,  -8, -42, -98,  17, -67,  58,  -1,-104, -34, -98, -45, -44,   6,  14,  77,  37;
/M: SY='N';  M= -91, -43,  60, -37,-100, -15,  12, -96, -13,   0, -93,  78, -42,  -4, -62,   2,   2, -21,  32, -43;
/M: SY='P';  M=   6,-104, -40,   4, -22,   1,  16, -15,  10, -19, -87,  14,  34,  -2, -32,  -7,  13,   7,  10,  30;
/I:         I=-18; MD=-45;
/M: SY='D';  M= -31,-112,  42,   6, -35, -74, -41, -57,   9, -62, -43,   7,  28,  25,  12,  21, -21, -31, -32,  -9; D=-18;
/I:         I=-18; MD=-45;
/M: SY='W';  M=  -6,-116, -37,  -3, -45, -32, -25, -42,   9, -32,  -8,  15,  27, -24, -36,  -1,   6, -56,  65, -35; D=-18;
/I:         I=-18; MD=-45;
/M: SY='M';  M= -18,-118,-118, -48, -32, -57, -26,  21, -45,  26,  30, -13, -63, -53, -61, -17, -61,  -6,-120, -30; D=-18;
/I:         I=-18; MD=-45;
/M: SY='K';  M= -32,-130,-120, -56,   1, -51, -61, -11,  17, -31, -20, -61,  15, -16,  14, -54, -47, -49,-125, -52; D=-18;
/I:         I=-18; MI=0; MD=-45; IM=0; DM=-45;
/M: SY='N';  M= -25,-116, -25, -42,-122, -40,  -5, -77, -13, -75,-114,  49,-114, -50, -65,  38,  33,-113,-134,-115; D=-18;
/I:         I=-18; DM=-45;
/M: SY='P';  M= -25, -35,   4,  -6, -71,   8, -56, -47,   1, -45, -36,   2,  50,  -2, -60,   0, -18, -68,  33,   5; D=-18;
/I:         I=-18; DM=-45;
/M: SY='G';  M= -30,-106,  42, -27, -11,  47, -34, -66, -58, -12, -97,  32,-103, -53, -17, -14,  33,-101, -29,  -5; D=-18;
/I:         I=-18; DM=-45;
/M: SY='N';  M= -42,  32,   1, -44, -48,  50, -31, -18, -89,  -3, -17,  65, -13,  -6, -32,  29, -85, -71, -34, -54;
/M: SY='W';  M=-105,-126,-128,-109,  27,-104, -15,-100,-102, -97,-100,-121, -60,-102,-105, -73,-114, -67, 177, -31;
/M: SY='G';  M= -56, -45, -35, -25,-102,  92, -98, -65, -50,   3,   7, -31, -52, -95,-103, -83, -38, -29,-104, -50;
/M: SY='P';  M=  -4,  -4,   9, -11,   6, -45,  -9,  28, -96,  26,  -1, -32,  57, -23,-101, -51,  -6,  15,-105, -47;
/M: SY='W';  M=   8,-104,-110,-104,  32, -32, -36,   8,-101,  45,  18, -19,-108, -99,-102, -33, -36, -16, 112,  20;
/M: SY='H';  M= -46,-109, -84, -84, -98, -99, 150, -70, -88, -98, -84, -38, -99, -47, -83, -30, -36, -72,-131, -69;
/M: SY='E';  M= -32,-110, -64, 112, -58, -51, -85,-110, -53, -57,-100, -87, -87, -35, -50, -56, -90, -70,-109,-101;
/M: SY='I';  M= -49,-102,-111,-107,   6,-113,-100,  66,-105,  52,  23, -58,-108, -55,-105, -53, -48,  20, -17,  31;
/M: SY='G';  M=   9,-104, -93,-102,-110,  99, -46,-114, -97,-112,-102,  -7, -98, -95,-104, -21, -94, -70,-104, -42;
/M: SY='H';  M= -69,-110, -57, -84, -56,-101, 150, -47, -88, -53, -31, -75,-100, -78, -36, -89, -57,-109,-127, -29;
/M: SY='N';  M=   1, -19, -50, -44,-102,  22,  63, -95, -85, -27, -18,  82,-100,  24, -33,   4, -15,  -1,-116, -93;
/M: SY='Y';  M= -74, -33, -97, -95,  43,-104,  60, -14, -90,   4,  47,  17,-107,  14,  10, -19, -26, -64, -84,  84;
/M: SY='Q';  M= -27,-111,  48,  20,-112, -97, -81, -17, -75, -35, -90,  -6, -96, 115, -78, -50, -89,-100,-108, -93;
/M: SY='Q';  M= -28, -38, -26,  -7,  39,   1,   7, -18,   3, -17,  22, -19, -15,  45,  19, -25,  11,   0, -29, -15;
/M: SY='G';  M=   3,-104, -36,  15,-101,  40, -27, -66, -27, -66, -39,  23,  27,   5,  14,  19,  19, -32,  15,   1;
/I:         I=-20; MI=0; MD=-51; IM=0; DM=-51;
/M: SY='P';  M=   3,-120,  14, -24,  35,   3, -36,-113, -65,-111, -22,-102,  40, -34,  21, -66,  -8, -83, -23,-101; D=-20;
/I:         I=-20; DM=-51;
/M: SY='W';  M= -25, -35, -51, -33,  27, -13, -47, -11, -64, -15,  24, -35,-114,-105, -68,-107,-106, -14, 132,   9; D=-20;
/I:         I=-20; DM=-51;
/M: SY='N';  M= -73,-105,  -7, -10,  16, -19, -53, -47,   4, -67, -11,  57, -23, -35,   2,   5,  51, -31,-114, -96; D=-20;
/I:         I=-20; DM=-51;
/M: SY='W';  M= -54,-112,  28, -98,  59,-104,-102, -44, -16, -77, -24,  -7,-109, -37, -48,  14, -39,  -5, 123,   5; D=-20;
/I:         I=-20; DM=-51;
/M: SY='W';  M= -12,-106,  27,   9, -43,  21, -33, -67,  17,-103, -97,  40,  34,   9,  -9,   4, -17, -23,  54,   5;
/I:         I=-31; MD=-79;
/M: SY='P';  M= -75,-122,  -8, -64,-107,  -2,  -8, -26, -56, -22,  29,-106,  31, -42, -11, -37,  16, -20,-119,  22; D=-31;
/I:         I=-31; MI=0; MD=-79; IM=0; DM=-79;
/M: SY='G';  M=   0,-104,  18, -46, -67,  51,  36, -32, -44, -74, -34,  24,  -3, -34,  -2,   6,  17, -12,  42, -17;
/M: SY='M';  M=  -1, -43, -41,  13,  -8, -39, -93, -14, -60,  28,  49, -40, -38,  -4, -66,   3,  48, -11,  24,  18;
/M: SY='T';  M= -20, -99, -59, -23,-101,  57, -43, -13, -89, -56, -14,  -4, -48, -32, -13,  27,  65, -11,-110, -98;
/M: SY='E';  M=  -5,-109, -33, 111, -62, -41, -10,-112, -74,-105,-101, -56, -87, -40, -83, -55, -90,-105,-110,-101;
/M: SY='V';  M=   0, -22, -59, -66, -87,-105,-107,  21, -99, -36, -34, -52,-103,-100,-103,  -3,  32,  85,-113, -37;
/M: SY='W';  M= -29, -98, -93, -61, -21, -64, -99, -66, -90, -62, -93, -29, -95,  -5, -95,  51,  88, -51, 107, -84;
/M: SY='N';  M= -47,  45, -28, -92, -98, -91, -40, -82, -87, -65, -90, 100, -38, -44, -94, -28,  18,  51, -19, -98;
/M: SY='N';  M= -45, -98, -34, -58,-105, -48, -32, -63, -80, -58, -97, 124,-103, -48, -88, -22, -77, -49,-123,-100;
/M: SY='I';  M= -48,-102,-112, -66, -17,-114,-106,  75,-104,  32,  26,-106, -58,-102, -39, -65, -88,  51, -13, -21;
/M: SY='Y';  M= -13,-105,-108,-105,  72,-107, -18, -10, -58,  30,   7, -63, -42, -99, -99, -71, -51, -82,  58,  88;
/M: SY='S';  M=  37,  29, -89, -56,-105, -17, -93,-101, -44, -77, -97,  17,  49, -86, -60,  73,  23, -94,-112,-101;
/M: SY='L';  M=  -3,-101,  32, -69, -46,-104, -46,   9, -45,  60,  20,   5,-106,   5, -97, -64, -26,   6,-103,  11;
/M: SY='Y';  M=  24, -42, -99, -42, -13, -68,  48,  18, -64,   3,  17, -59, -48,  -7,   3, -32, -36, -27, -86,  87;
/M: SY='Y';  M=  29, -45, -66, -98,  25, -60, -92,   0, -44,  -9,  45, -22,-104, -40, -97,   5,   4,  41, -93,  58;
/M: SY='Q';  M= -67,  33, -39,   9, -42, -31,  35, -36, -17, -27,  38,  -3, -54,  96, -25, -22, -56, -66,-100,  34;
/M: SY='Y';  M= -22,-106,  22,  34,   1,-100, -16, -17,  -6, -47, -36, -37, -98,  28,  34,   1,  26, -54,  40,  53;
/M: SY='M';  M=  -7,-102, -13,   2,   1, -30,  11,  -8,  30,   3,  44, -33, -99,  -2,  34, -30,  35, -42,-103, -12;
/M: SY='W';  M= -48,-104, -22, -47,  34, -56,   9,  10, -35,  17,  42,  12,-106, -93,  -9, -66,   2,  13,  72,  57;
/M: SY='M';  M= -28,  -8,  -7,  11,  -7,  25, -14, -37, -33,  21,  51,  10,  10, -15, -25, -21,  28, -68,-104,  -7;
/M: SY='G';  M= -48,-103,  13,   6, -63,  52,  -3, -72,   2, -50, -49,  49, -17,  -9,   4,   8,  17, -32,-110, -46;
/M: SY='P';  M=   0,-105,  -1,  22,   6, -37, -93,  30,  22, -50, -87,  -9,  31,  -7,   0, -14,  -1,   9, -15,  -1;
/M: SY='D';  M=  17,-102,  49,   8, -62,  -8,   2, -65,   5, -31,  25,   1,  14,  -3, -45,  29,  16, -64,-110, -27;
/M: SY='R';  M=  -9,-106,  -9,  27, -21,   5, -13, -20, -10, -61, -45,  13,  39, -16,  49,  17, -21, -22,-106, -18;
/M: SY='R';  M= -10,-106,   0,  -7,   5, -30,  -1, -18,  -8,  -2,   4, -21, -11, -15,  54, -31,   5, -36,  41,  44;
/I:         I=-13; MD=-33;
/M: SY='Q';  M= -71,-109,  19,  11, -61, -71,   8,   2,   7,   4, -19,  20, -39,  40,  32, -20, -26,  -5,   3, -16; D=-13;
/I:         I=-13; MD=-33;
/M: SY='H';  M=   9, -47, -15,  10, -34, -38,  26, -75,   8, -11, -95,   3, -24,   0,   8, -22,  14,  -8,-114,  -9; D=-13;
/I:         I=-13; MD=-33;
/M: SY='H';  M= -43,  18,  26,  17, -60,   1,  45, -37, -10, -30,-103,   0, -22,   6, -37,  -7, -61, -48,  -5, -22; D=-13;
/I:         I=-13; MD=-33;
/M: SY='W';  M=   0,  24,   8,  -7, -66,  12,  12, -33, -67, -81, -23, -11,   2,-101, -20,  -1, -58,-112,  85,-102; D=-13;
/I:         I=-13; MD=-33;
/M: SY='W';  M= -43, -38, -27, -17, -12, -19, -42, -52,-109,   5,  15, -29,-120, -14, -24,  -5,   9, -71,  58, -46; D=-13;
/I:         I=-13; MD=-33;
/M: SY='W';  M= -85, -35, -67, -49, -48, -16, -16,   1, -72, -10, -17,  11, -33,  -8, -63, -53,-113, -13,  38,  24; D=-13;
/I:         I=-13; MI=0; MD=-33; IM=0; DM=-33;
/M: SY='Q';  M= -33,-129, -38, -17, -48,  -1,  33,-124, -25, -51, -20,  10, -49,  37, -14, -26, -68,-123,   1, -20; D=-13;
/I:         I=-13; DM=-33;
/M: SY='R';  M= -13,-123, -47, -66,  -6, -38,-107, -11,   0, -43,   0, -55,  17,  20,  35, -46, -25, -43, -29, -28; D=-13;
/I:         I=-13; DM=-33;
/M: SY='E';  M= -30,-116,  18,  28,-116, -18, -34, -71,   3, -86,-107,  21,  27,  11, -32,   7,   6, -59,-120, -17; D=-13;
/I:         I=-13; DM=-33;
/M: SY='W';  M= -27, -12,  -3,  -5,   2,   0, -99, -12, -71, -44, -50,   8,-108,  18,  -4,  19,   3,  -8,  50,   6; D=-13;
/I:         I=-13; DM=-33;
/M: SY='R';  M= -26, -44,  38,  -8, -72, -28,   2, -38, -24, -50, -11,  25, -37,  31,  42,   0, -62,  13,-114, -17; D=-13;
/I:         I=-13; DM=-33;
/M: SY='W';  M=   2, -39,  -8,  44, -25, -76, -93,   3,   4, -22, -49, -33,  19,  22, -19, -20, -61, -25,  55,  37; D=-13;
/I:         I=-13; DM=-33;
/M: SY='D';  M= -10, -48,  43, -17,-104,  -3, -87, -65,  37, -34,  -2,  35,   7,  34,  14,   3,   9, -69,-110, -32;
/M: SY='A';  M=  31,-101, -26,  -3,  -8, -29, -91,  -5,  15, -16, -44,  24, -33, -12,  24,   1,   7,  -4,  12,   9;
/M: SY='I';  M=  13,-102, -14, -40,  -6,  -7, -40,  49, -20,  10,   8, -37, -27, -47, -38, -52, -20,  37,  42, -26;
/M: SY='W';  M=  -3,-105, -45,  -4,  10,   7, -90, -65,  39,  -8,   6,  15,  16,  27,   1, -19, -13, -23,  41,  10;
/M: SY='N';  M=  15,-102,  22,  26,-103, -43,   5, -52,   6, -41, -21,  59, -55,  26,  17,  25,  -7, -97,-111, -25;
/M: SY='Y';  M=  -7,-105, -14, -37,  35,-104, -10,  14, -37,  12, -14,  -5, -66, -53, -24, -47, -12, -18,  52,  86;
/M: SY='I';  M= -15,-102, -66, -72,  18,-110, -98,  61, -77,  48,  -1, -24,-107, -34,-103, -65,  -6,  10, -96,  32;
/M: SY='N';  M=  33,-101,  20,  15, -56, -46,  -8, -64,  16, -75,  25,  41, -38, -14,   2,  12,  11, -33,-105,  23;
/M: SY='N';  M=  24,-101,   6,   1, -56, -16, -31, -66,  31, -44, -14,  47, -97,  24,  -1,  44, -21, -60, -20, -48;
/M: SY='G';  M=  -3,-104,   8,   1,   2,  49,  -5, -34,  -5, -33, -36,  33,   3, -50, -10,  12, -25, -39,  12, -19;
/M: SY='N';  M=   5, -16,   9,  -7, -37, -15,  23,  -8,   1, -30,  12,  30, -12,  20,   0,  -7,   1,  14,   8,   0;
/M: SY='P';  M=  -3,-104,  15, -12,-101,  17,   7, -34,  10, -57, -95,  28,  39, -21,  -6,  24,  30, -68,  23,  -2;
/M: SY='Y';  M= -53,-105,   1,   8,  40,  -4,  23, -47,  -8,  -7, -87,  15,  25,   5, -92, -16,   5, -18,  35,  53;
/M: SY='N';  M=   8,-103,  28,  17, -21, -44,   2, -66,  18, -58,   3,  47,  17,  -4, -13,   6,  10, -42,-105,  24;
/M: SY='W';  M=  -6,-104,  32,  -2,   5, -52, -48, -19,  15, -30,  -6,  24, -12,  23,   4,  18,   5, -11,  40,   0;
/M: SY='W';  M=  -3,-109,  27, -48,  21,  -2,  15, -25, -19, -28, -29, -38,  12, -14, -30,   9, -26, -67, 120,  10;
/I:         I=-19; MD=-49;
/M: SY='D';  M=  -7,-112,  29, -15, -36,   6,  -3, -23,  -6, -27,-100,  20, -33,  19, -43,  13,  -7, -38,-118, -45; D=-19;
/I:         I=-19; MI=0; MD=-49; IM=0; DM=-49;
/M: SY='W';  M=   2,-115,  13,  12, -73, -12, -46, -30, -14, -68,-105,   4, -45, -24, -58,  22, -11, -36,  68,  14; D=-19;
/I:         I=-19; DM=-49;
/M: SY='D';  M= -69, -53,  69,  10,-104,   9,  -2, -47, -32, -48, -97,  50,   4,  18, -12,   2,   3, -40,   0, -18;
/M: SY='P';  M=   3,-103, -23,   8,  22, -57,  11, -13, -65,  16,   1,  22,  44, -92, -68, -44,  -6,  28,  28,   2;
/M: SY='W';  M= -38, -47, -20,   6,  76,  10,  -4, -65, -49, -23, -38, -14, -53, -50,  31, -11,  -3, -94,  90, -41;
/M: SY='T';  M=  -6,  -7,  29,  38, -56, -24,  26,   6, -13, -21, -24, -34, -36,  -1, -16, -14,  40,   2,-109, -10;
/M: SY='R';  M=  27, -49, -54, -82,-101, -14,   2, -36,  47, -37,  12, -86,  -2,  46,  59, -43, -27, -35,-104, -15;
/M: SY='L';  M= -53,-100, -62,-104,   1,-113, -98, -33,-105,  86,  24,-110,-112, -28,-103,-104, -42, -23,  43, -80;
/M: SY='V';  M=  20, -16, -29, -10,  31,  -5, -40,  22, -60,  -4,  -9, -34,-103, -15, -17, -17,  -1,  35, -99,  21;
/M: SY='M';  M= -35,-101,-105,-100,  63, -43, -22,   5, -60, -25,  95, -96,  28, -95, -99,  16,  20, -18,  25, -44;
/M: SY='Y';  M=-100,-105, -58,-105,  81, -71,  -7, -28, -63,  33,   0, -57,-112, -48, -99,-100, -59, -83,   8,  92;
/M: SY='W';  M=  23, -34, -31,  -4, -87,  -1, -49, -35, -93,   3,  36, -51,-101, -55, -20, -16,  24,  25, 107, -15;
/M: SY='Q';  M= -91,-109,  -8, -13, -27, -98, -29, -69, -40,   3,  -3,  18, -37, 107,   7,  -8, -24, -70,  25, -52;
/M: SY='L';  M= -95,-101, -38, -41,   3,-110, -45,  15, -63,  73,  52, -10, -34, -97,-101, -43, -29, -13,  11, -43;
/M: SY='M';  M=   5, -34, -65,   8,  -6, -53,  36,   9,  20,   2,  43, -40,-101,  36,  19, -24, -40,  -5,   5,  12;
/M: SY='H';  M= -67, -32,  10,  20,  10, -48,  41, -14, -37,  32, -17,  37,-102,  19, -19,  -5, -37, -18,-100,  33;
/M: SY='Y';  M=  38,-101, -62, -48, -22, -11,  15, -63,  31, -58, -22, -18, -54,  -2, -33,  15,  17, -11,  50,  57;
/M: SY='F';  M=  20, -43,  -6, -99,  82, -49, -92,   3, -40, -11, -20, -52,-107, -29, -65, -22, -58, -27,  41,  61;
/M: SY='G';  M= -20, -38,   3,   3, -56,  84,  -2, -49, -32,-109,-100,  -2,   0, -14, -44, -25, -26,-106,-106, -34;
/I:         E1=0; IE=-380; DE=-380;
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2020_04 which contains 563'082 sequence entries.


Total number of hits 21 in 21 different sequences
Number of true positive hits 21 in 21 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 1
Feature key [info] DOMAIN
Feature description [info] Peptidase M60
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
21 sequences

ACFD_ECOH1  (E3PJ90    ), ACFD_ECOLI  (P0CK95    ), ACFD_VIBC3  (A5F372    ), 
ACFD_VIBCH  (P0C6F0    ), APRN_ENTHI  (P20301    ), APRP_ENTHI  (P20302    ), 
IMPA_PSEAE  (Q9I5W4    ), TCAF1_BOVIN (A5PJN5    ), TCAF1_HUMAN (Q9Y4C2    ), 
TCAF1_MOUSE (Q8BNE1    ), TCAF1_PONAB (Q5R8R3    ), TCAF2_BOVIN (A6QLU7    ), 
TCAF2_HUMAN (A6NFQ2    ), TCAF2_MOUSE (Q921K8    ), TCAF3_MOUSE (Q6QR59    ), 
TCAF3_RAT   (Q6P6V7    ), TCAF_DANRE  (A4IG42    ), TCAF_XENLA  (Q5XHI4    ), 
VEF_GVHA    (P54232    ), VEF_GVPU    (P41723    ), VEF_GVTN    (P29998    )
» more

PDB
[Detailed view]
3 PDB

5KDV; 5KDW; 5KDX

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