ProRule PRU01064
General rule information
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| Accession | PRU01064 |
| Dates | 20-SEP-2016 (Created)
3-SEP-2024 (Last updated, Version 7) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51728; RTT109_HAT |
Name | Rtt109-type histone acetyltransferase (HAT) domain |
| Function | Rtt109, also known as KAT11, is a recently characterized fungal- specific HAT that modifies histone H3 lysine 56 (H3K56) to promote genome stability and resistance to a variety of DNA-damaging agents. |
| Scope(s) |
Eukaryota Ascomycota |
| Example(s) | Q5AAJ8 (RT109_CANAL); |
Propagated annotation
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Identifier, protein and gene names
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| Protein name | + RecName: EC=2.3.1.48; |
Comments
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| CATALYTIC ACTIVITY | Reaction=L-lysyl-[protein] + acetyl-CoA = N(6)-acetyl-L-lysyl-[protein] + CoA + H(+); Xref=Rhea:RHEA:45948, Rhea:RHEA-COMP:9752, Rhea:RHEA-COMP:10731, ChEBI:CHEBI:15378, ChEBI:CHEBI:29969, ChEBI:CHEBI:57287, ChEBI:CHEBI:57288, ChEBI:CHEBI:61930; EC=2.3.1.48; |
| SIMILARITY | Belongs to the RTT109 family. |
Keywords
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Features
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| From: PS51728 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="Rtt109-type HAT #" | |||||||||
Additional information
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| Size range | 336-413 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [5] All [ 5 ]
- Retrieve set of proteins with 3D structure for this domain