Home  |  Contact
annotation rule: PRU01064

General rule information [?]

Accession PRU01064
Dates 20-SEP-2016 (Created)
22-NOV-2019 (Last updated, Version 6)
Data class Domain
Predictors PROSITE; PS51728; RTT109_HAT
Name Rtt109-type histone acetyltransferase (HAT) domain
Function Rtt109, also known as KAT11, is a recently characterized fungal- specific HAT that modifies histone H3 lysine 56 (H3K56) to promote genome stability and resistance to a variety of DNA-damaging agents.

Propagated annotation [?]


Description [?]

+ RecName: EC 2.3.1.48;

Comments [?]

Catalytic activity RHEA:45948: acetyl-CoA + L-lysyl-[protein] = CoA + H(+) + N(6)-acetyl-L-lysyl-[protein]
EC 2.3.1.48
Similarity Belongs to the RTT109 family.

Keywords [?]

DNA damage

Features [?]

From: PS51728
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       Rtt109-type HAT #        

Additional information [?]

Size range 336-413 amino acids
Related rules None
Repeats 1
Topology Undefined
Example Q5AAJ8 (RT109_CANAL)
Scope
Eukaryota; Ascomycota
Comments None

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.


View rule in raw text format (no links)


UniProtKB rule member sequences [?]