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| annotation rule: PRU01064 |
General rule information
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| Accession | PRU01064 |
| Dates | 20-SEP-2016 (Created) 22-NOV-2019 (Last updated, Version 6) |
| Data class | Domain |
| Predictors | PROSITE; PS51728; RTT109_HAT |
| Name | Rtt109-type histone acetyltransferase (HAT) domain |
| Function | Rtt109, also known as KAT11, is a recently characterized fungal- specific HAT that modifies histone H3 lysine 56 (H3K56) to promote genome stability and resistance to a variety of DNA-damaging agents. |
Propagated annotation
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Description
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| + RecName: EC 2.3.1.48; |
Comments
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| Catalytic activity | RHEA:45948: acetyl-CoA + L-lysyl-[protein] = CoA + H(+) + N(6)-acetyl-L-lysyl-[protein]
EC 2.3.1.48 |
| Similarity | Belongs to the RTT109 family. |
Keywords
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Features
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| From: PS51728 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | Rtt109-type HAT # | |||||||||
Additional information
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| Size range | 336-413 amino acids |
| Related rules | None |
| Repeats | 1 |
| Topology | Undefined |
| Example | Q5AAJ8 (RT109_CANAL) |
| Scope | Eukaryota; Ascomycota |
| Comments | None |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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UniProtKB/Swiss-Prot sets
Eukaryota [3]
- Retrieve set of proteins with 3D structure for this domain