ProRule PRU01064

General rule information [?]

Accession PRU01064
Dates 20-SEP-2016 (Created)
22-NOV-2019 (Last updated, Version 6)
Data class Domain;
Predictors PROSITE; PS51728; RTT109_HAT
Name Rtt109-type histone acetyltransferase (HAT) domain
Function Rtt109, also known as KAT11, is a recently characterized fungal- specific HAT that modifies histone H3 lysine 56 (H3K56) to promote genome stability and resistance to a variety of DNA-damaging agents.
Scope(s) Eukaryota
Example(s) Q5AAJ8 (RT109_CANAL);

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name + RecName: EC=;

Comments [?]

CATALYTIC ACTIVITY Reaction=acetyl-CoA + L-lysyl-[protein] = CoA + H(+) + N(6)-acetyl-L- lysyl-[protein]; Xref=Rhea:RHEA:45948, Rhea:RHEA-COMP:9752, Rhea:RHEA-COMP:10731, ChEBI:CHEBI:15378, ChEBI:CHEBI:29969, ChEBI:CHEBI:57287, ChEBI:CHEBI:57288, ChEBI:CHEBI:61930; EC=;
SIMILARITYBelongs to the RTT109 family.

Keywords [?]

Features [?]

From: PS51728
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="Rtt109-type HAT #"

Additional information [?]

Size range 336-413 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined


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UniProtKB rule member sequences [?]