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| annotation rule: PRU01070 |
General rule information
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| Accession | PRU01070 |
| Dates | 14-OCT-2014 (Created) 22-NOV-2019 (Last updated, Version 6) |
| Data class | Domain |
case <OC:Bacteria>
| Predictors | PROSITE; PS00409; PROKAR_NTER_METHYL |
end case
| Name | Prokaryotic N-terminal methylation |
| Function | Gram-negative bacteria produce pilin which are characterized by the presence of a very short leader peptide of 6 to 7 residues, followed by a methylated N-terminal phenylalanine residue and by a highly conserved sequence of about 24 hydrophobic residues. This class of pilin is often referred to as NMePhe or type-4 pili. |
Propagated annotation
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Description
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| Flags: Precursor; |
Features
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| From: PS00409 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| PROPEP | Nter | 2 | ||||||||||
| CHAIN | 3 | Cter |
|
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| MOD_RES | 3 | 3 | N-methylphenylalanine | F | ||||||||
| MOD_RES | 3 | 3 | N-methyltyrosine | Y | ||||||||
| MOD_RES | 3 | 3 | N-methylleucine | L | ||||||||
| MOD_RES | 3 | 3 | N-methylisoleucine | I | ||||||||
| MOD_RES | 3 | 3 | N-methylmethionine | M | ||||||||
Additional information
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| Size range | 11-31 amino acids |
| Related rules | None |
| Repeats | 1 |
| Topology | Undefined |
| Example | P02975 (FMAA_DICNO) |
| Scope | Bacteria |
| Comments | None |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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