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annotation rule: PRU01071

General rule information [?]

Accession PRU01071
Dates 24-OCT-2014 (Created)
22-NOV-2019 (Last updated, Version 3)
Data class Domain
Predictors PROSITE; PS51735; VP35_IID
Names Filoviruses VP35 interferon inhibitory domain profile; VP35 IID domain
Function VP35 contains an N-terminal coiled-coil domain required for its oligomerization and a C-terminal interferon (IFN) inhibitory domain (IID). The VP35 IID can bind dsRNA and VP35-mediated IFN antagonism correlates with dsRNA-binding activity.

Propagated annotation [?]


Comments [?]

Similarity Belongs to the filoviridae polymerase cofactor VP35 family.

Features [?]

From: PS51735
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       VP35 IID #        

Additional information [?]

Size range 116-136 amino acids
Related rules None
Repeats 1
Topology Undefined
Example Q6UY68 (VP35_MABVO)
Scope
Viruses; Filoviridae
Comments None

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.



UniProtKB rule member sequences [?]