ProRule PRU01071

General rule information [?]

Accession PRU01071
Dates 24-OCT-2014 (Created)
22-NOV-2019 (Last updated, Version 3)
Data class Domain;
Predictors PROSITE; PS51735; VP35_IID
Name Filoviruses VP35 interferon inhibitory domain profile
Function VP35 contains an N-terminal coiled-coil domain required for its oligomerization and a C-terminal interferon (IFN) inhibitory domain (IID). The VP35 IID can bind dsRNA and VP35-mediated IFN antagonism correlates with dsRNA-binding activity.
Scope(s) Viruses
Example(s) Q6UY68 (VP35_MABVO);

Propagated annotation [?]

Comments [?]

SIMILARITYBelongs to the filoviridae polymerase cofactor VP35 family.

Features [?]

From: PS51735
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="VP35 IID #"

Additional information [?]

Size range 116-136 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined


PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

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UniProtKB rule member sequences [?]