PRU01071
General rule information
[?]
| Accession | PRU01071 |
| Dates | 24-OCT-2014 (Created) 22-NOV-2019 (Last updated, Version 3) |
| Data class | Domain |
| Predictors | PROSITE; PS51735; VP35_IID |
| Names | Filoviruses VP35 interferon inhibitory domain profile; VP35 IID domain |
| Function | VP35 contains an N-terminal coiled-coil domain required for its oligomerization and a C-terminal interferon (IFN) inhibitory domain (IID). The VP35 IID can bind dsRNA and VP35-mediated IFN antagonism correlates with dsRNA-binding activity. |
Propagated annotation
[?]
Comments
[?]
| Similarity | Belongs to the filoviridae polymerase cofactor VP35 family. |
Features
[?]
| From: PS51735 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | VP35 IID # | |||||||||
Additional information
[?]
| Size range | 116-136 amino acids |
| Related rules | None |
| Repeats | 1 |
| Topology | Undefined |
| Example | Q6UY68 (VP35_MABVO) |
| Scope | Viruses; Filoviridae |
| Comments | None |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
[?]
-
UniProtKB/Swiss-Prot sets
Viruses [10]
- Retrieve set of proteins with 3D structure for this domain