ProRule PRU01129

General rule information [?]

Accession PRU01129
Dates 5-APR-2016 (Created)
19-NOV-2022 (Last updated, Version 7)
Data class Domain;
Predictors PROSITE; PS51793; MIS18
Name Mis18 domain
Function The oligomerization of Mis18, mediated by its conserved N-terminal globular domain, is crucial for its centromere localization and function.
Scope(s) Eukaryota
Example(s) A5D7N9 (MS18A_BOVIN);

Propagated annotation [?]

Comments [?]

SIMILARITYBelongs to the mis18 family.

Keywords [?]

Gene Ontology [?]

GO:0000775; Cellular component:chromosome, centromeric region
case <FTGroup:1>
GO:0008270; Molecular function:zinc ion binding

Features [?]

From: PS51793
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="Mis18 #"
BINDING 6 6 /ligand="Zn(2+)"
C 1
BINDING 9 9 /ligand="Zn(2+)"
C 1
BINDING 63 63 /ligand="Zn(2+)"
C 1
BINDING 66 66 /ligand="Zn(2+)"
C 1

Additional information [?]

Size range 87-110 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined


PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

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UniProtKB rule member sequences [?]