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| annotation rule: PRU01129 |
General rule information
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| Accession | PRU01129 |
| Dates | 5-APR-2016 (Created) 22-NOV-2019 (Last updated, Version 5) |
| Data class | Domain |
| Predictors | PROSITE; PS51793; MIS18 |
| Name | Mis18 domain |
| Function | The oligomerization of Mis18, mediated by its conserved N-terminal globular domain, is crucial for its centromere localization and function. |
Propagated annotation
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Comments
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| Similarity | Belongs to the mis18 family. |
Gene Ontology
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GO:0000775; Cellular component: chromosome, centromeric region.
case <FTGroup:1>
GO:0008270; Molecular function: zinc ion binding.
Keywords
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end case
Features
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| From: PS51793 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | Mis18 # | |||||||||
| METAL | 6 | 6 | Zinc | C | 1 | |||||||
| METAL | 9 | 9 | Zinc | C | 1 | |||||||
| METAL | 63 | 63 | Zinc | C | 1 | |||||||
| METAL | 66 | 66 | Zinc | C | 1 | |||||||
Additional information
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| Size range | 87-110 amino acids |
| Related rules | None |
| Repeats | 1 |
| Topology | Undefined |
| Example | A5D7N9 (MS18A_BOVIN) |
| Scope | Eukaryota |
| Comments | None |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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-
UniProtKB/Swiss-Prot sets
Eukaryota [10]
- Retrieve set of proteins with 3D structure for this domain