PRU01129
General rule information
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| Accession | PRU01129 |
| Dates | 5-APR-2016 (Created) 19-NOV-2022 (Last updated, Version 7) |
| Data class | Domain |
| Predictors | PROSITE; PS51793; MIS18 |
| Name | Mis18 domain |
| Function | The oligomerization of Mis18, mediated by its conserved N-terminal globular domain, is crucial for its centromere localization and function. |
Propagated annotation
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Comments
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| Similarity | Belongs to the mis18 family. |
Gene Ontology
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GO:0000775; Cellular component: chromosome, centromeric region.
case <FTGroup:1>
GO:0008270; Molecular function: zinc ion binding.
Keywords
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end case
Features
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| From: PS51793 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | Mis18 # | |||||||||
| BINDING | 6 | 6 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105 | C | 1 | |||||||
| BINDING | 9 | 9 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105 | C | 1 | |||||||
| BINDING | 63 | 63 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105 | C | 1 | |||||||
| BINDING | 66 | 66 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105 | C | 1 | |||||||
Additional information
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| Size range | 87-110 amino acids |
| Related rules | None |
| Repeats | 1 |
| Topology | Undefined |
| Example | A5D7N9 (MS18A_BOVIN) |
| Scope | Eukaryota |
| Comments | None |
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UniProtKB rule member sequences
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UniProtKB/Swiss-Prot sets
Eukaryota [10]
- Retrieve set of proteins with 3D structure for this domain