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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU01141


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU01141
General rule information [?]

Accession PRU01141
Dates 24-MAY-2016 (Created)
19-NOV-2022 (Last updated, Version 7)
Data class Domain;
Predictors PROSITE; PS51800; ZF_CHHC_U11_48K
Name Zinc finger CHHC U11-48K-type
Function The CHHC U11-48K-type zinc finger may function as a RNA recognition and binding module.
Scope(s) Eukaryota
Eutheria
Example(s) Q4R8M9;

Propagated annotation [?]

Keywords [?]

Metal-binding
Zinc
end case
Zinc-finger

Gene Ontology [?]

case <Feature:PS51800:4=[CH]> and <Feature:PS51800:10=[CH]> and <Feature:PS51800:20=[CH]> and <Feature:PS51800:24=[CH]>
GO:0046872; Molecular function:metal ion binding

Features [?]

From: PS51800
Key From To Description Tag Condition FTGroup
case <Feature:PS51800:4=[C]> and <Feature:PS51800:10=[H]> and <Feature:PS51800:20=[H]> and <Feature:PS51800:24=[C]>
ZN_FING from to /note="CHHC U11-48K-type #"
else case <Feature:PS51800:4=[CH]> and <Feature:PS51800:10=[CH]> and <Feature:PS51800:20=[CH]> and <Feature:PS51800:24=[CH]>
ZN_FING from to /note="CHHC U11-48K-type #; atypical"
else
ZN_FING from to /note="CHHC U11-48K-type #; degenerate"
end case
BINDING 4 4 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"		 [CH] 1
BINDING 10 10 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"		 [CH] 1
BINDING 20 20 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"		 [CH] 1
BINDING 24 24 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"		 [CH] 1

Additional information [?]

Size range 18-38 amino acids
Related rules None
Fusion None
Repeats 2
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]