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ProRule PRU01142


General rule information [?]

PURL https://purl.expasy.org/prosite/rule/PRU01142
Accession PRU01142
Dates 3-JUN-2016 (Created)
19-NOV-2022 (Last updated, Version 6)
Data class Domain;
Predictors PROSITE; PS51801; ZF_CCHC_NOA
Name Zinc finger CCHC NOA-type
Function The CCHC NOA (NEMO Optineurin ABIN2)-type zinc finger has been shown to function as an ubiquitin-binding domain.
Scope(s) Eukaryota
Metazoa
Example(s) Q95KA2 (OPTN_MACFA);

Propagated annotation [?]

Keywords [?]

Metal-binding
Zinc
end case
Zinc-finger

Gene Ontology [?]

case <Feature:PS51801:9=[CH]> and <Feature:PS51801:12=[CH]> and <Feature:PS51801:25=[CH]> and <Feature:PS51801:29=[CH]>
GO:0046872; Molecular function:metal ion binding

Features [?]

From: PS51801
Key From To Description Tag Condition FTGroup
case <Feature:PS51801:9=C> and <Feature:PS51801:12=C> and <Feature:PS51801:25=H> and <Feature:PS51801:29=C>
ZN_FING from to /note="CCHC NOA-type #"
else case <Feature:PS51801:9=[CH]> and <Feature:PS51801:12=[CH]> and <Feature:PS51801:25=[CH]> and <Feature:PS51801:29=[CH]>
ZN_FING from to /note="CCHC NOA-type #; atypical"
else
ZN_FING from to /note="CCHC NOA-type #; degenerate"
end case
BINDING 9 9 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"		 [CH] 1
BINDING 12 12 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"		 [CH] 1
BINDING 25 25 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"		 [CH] 1
BINDING 29 29 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"		 [CH] 1

Additional information [?]

Size range 21-43 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.



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UniProtKB rule member sequences [?]