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PROSITE entry PS51801


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General information about the entry

Entry name [info] ZF_CCHC_NOA
Accession [info] PS51801
Entry type [info] MATRIX
Date [info] 01-JUN-2016 CREATED;
13-FEB-2019 DATA UPDATE;
27-MAR-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC51801
Associated ProRule [info] PRU01142

Name and characterization of the entry

Description [info] Zinc finger CCHC NOA-type profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=31;
/DISJOINT: DEFINITION=PROTECT; N1=4; N2=28;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.3267822; R2=0.0114355; TEXT='-LogE';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=3317.8935547; R2=0.5922078; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=1109; H_SCORE=3975; N_SCORE=15.0; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=365; H_SCORE=3534; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-102; D=-100; I=-100; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255;
...
                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-255; BD=-255;
/M: SY='Q';  M=  21,  -6,-208, -23, -46,  -5, -19, -67, -21, -85,-209, -17,  60,  76,  31, -17,  -1, -40,   3, -63;
/M: SY='R';  M= -60,-227,  -8,  39, -68, -32, -48,-219,-105, -57,-211,-131,  67,  39,  68, -31,  16, -67, -78,  17;
/M: SY='G';  M=  -1,-220,   9,  33,-223,  49,  -7,-220,-131, -39, -92,  37,  25, -17, -30,  29,  19, -66,-228,-217;
/M: SY='Q';  M=  -9,-223, -21, -12, -73, -39,-209,  33, -27,  11,   7, -69,  36,  75,   9,   3, -13, -40,-223,-210;
/M: SY='P';  M=  -1,-222, -17, -15,-226,  36, -39,-222,-206,-140,-216, -49,  81,  -5, -47,  61,  10,-218,-227, -79;
/M: SY='D';  M= -25,-222,  68,  57, -83, -78,-207,  32, -37, -26,  19, -18,-213,  -3, -53, -35,  18, -12,-230,-212;
/M: SY='H';  M=-216,-220,-222,-218,  38,-228,  85, -58,-100,  75, -56, -62,-228,-102, -81,-218,-212,-197,-209,  56;
/M: SY='Q';  M= -13,  41,-207, -32,-216,-214, -14, -12, -40, -37, -18, -15,-217,  90,  46,  39, -63, -33, -12,   4;
/M: SY='C';  M=-208, 162,-228,-228,-219,-224,-228,-225,-224,-216,-216,-214,-239,-232,-231,-211,-208,-213,-248,-229;
/M: SY='P';  M=-214,-239,-214,-202,-233,-215,-217,-221,-210,-231,-218,-220, 136,-214,-223,-211,-206,-226,-226,-231;
/M: SY='K';  M= -66,-224,-210,-200,-212, -71,  72,  36,  80,   7,-199,-202,-217,   0,  38, -84,-207, -63,-222, -40;
/M: SY='C';  M=-208, 162,-228,-228,-219,-224,-228,-225,-224,-216,-216,-214,-239,-232,-231,-211,-208,-213,-248,-229;
/M: SY='M';  M= -21,-218, -25, -19,   9,  17,   3,-204, -62,  36,  59,  47,-219,  39,-209,  32, -76,-206,-221, -41;
/M: SY='Q';  M=  11,  -6,-100,  38,  -3, -29,-203,   8,  38, -88, -10, -18,-216,  49,  43,-203, -30,-209,-214,  42;
/M: SY='C';  M= -41,  48,-214,-212,  -9,  15, -16,  33, -16, -58,   2,-112, -66,  16,  -2,  35,  42,  20,-224, -59;
/M: SY='F';  M=   6,  38,-229,-225, 107,-225,-210,-196,-222,  17,-195,-222,-230,-225,-220,-215, -57, -75,-194,  61;
/M: SY='P';  M=-206,  26,  11,-201,-225, -76, -73,-222,   7,-226,-216,  47,  84,-201,  38,  48,   6,-220,-229, -57;
/M: SY='D';  M= -24,-224, 114,   0,-231,-209,-201,-229,-201,-229,-226,  29,-213,-200,-209,  10, -10,-224,-244,-218;
/M: SY='M';  M= -81,-222, -24,  37, -17, -82,-212,  33, -12,  53,  63,-216,-221, -37, -55,-214,   6, -93,-219,   6;
/I:         I=-28; MI=0; MD=-71; IM=0; DM=-71;
/M: SY='D';  M=  18,-222,  87,  39,-228, -97, -30,-222, -45,-222, -18, -43,-213, -10,-208,  25,  25, -43,-237,-217;
/M: SY='T';  M= -28,-217,-198,  64,-221,-214,-210, -69, -94,-215, -18, -18, -40, -12,-209,  45,  78,   1,-232,-216;
/M: SY='L';  M= -68,  25,-231,-225,  33,-232,-213,-186,-225,  87,-182,-229,-233,-220,-223,-223,-212, -79,-210,  44;
/M: SY='Q';  M=-210,-226,-206,  36,   4,-221,-203,-207, -58,  35,   9, -61,-218, 111,-199, -66, -61, -63,-220,-205;
/M: SY='I';  M= -93,-223, -55,  23,-214, -80, -49,  63,  25, -32,-203,  59,-218,-110,  30,  33,-202,-198,-228,-212;
/M: SY='H';  M=-219,-231,-203,-203,-218,-221, 157,-236,-208,-218,-203,-192,-220,-197,-202,-209,-218,-235,-253,-186;
/M: SY='V';  M=   8,  54,-232,-226, -13,-229,-231,  29,-224, -27, -18,-226,-228,-225,-226,-215,-205,  86,  24,-209;
/M: SY='M';  M=  24,-219,  12,  29,-218,-212,   6,-208,-206, -65,  90,  54, -35, -42,-211,  13,  15, -33,-233,-213;
/M: SY='D';  M=-213,-231,  90,  80, -59,-220, -34,-229,-198,-226, -35,-196,-213,  18, -62, -58,-209, -63,-234,  -6;
/M: SY='C';  M=-212, 157,-230,-230, -44,-227,   2,-228,-226,-218,-218,-217,-241,-233,-119,-214,-212,-216,-249,-228;
/M: SY='C';  M=  20,  87,-231,-227, -37,-228,-226,  70,-105,  36,  23,-223, -56,-222,-227,-216,-209, -42,-227,-210;
/M: SY='Q';  M= -76, -34,  69, -20,-229,   6, -24,  -3,  -5, -60,-216,  16,-219,  73,   1, -15, -52,-220,-234,-217;
/I:         E1=0; IE=-255; DE=-255;
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_02 which contains 571'282 sequence entries.


Total number of hits 18 in 18 different sequences
Number of true positive hits 18 in 18 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Feature key [info] ZN_FING
Feature description [info] CCHC NOA-type
Version [info] 3

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
18 sequences

NEMO_BOVIN  (Q95KU9), NEMO_DROME  (Q9GYV5), NEMO_HUMAN  (Q9Y6K9), 
NEMO_MOUSE  (O88522), NEMO_PIG(A9QT41), NEMO_RAT(Q6TMG5), 
OPTN_CHICK  (Q90Z16), OPTN_DANRE  (Q5RI56), OPTN_HUMAN  (Q96CV9), 
OPTN_MACFA  (Q95KA2), OPTN_MACMU  (Q861Q8), OPTN_MOUSE  (Q8K3K8), 
OPTN_PIG(Q7YS99), OPTN_PONAB  (Q5R923), OPTN_RAT(Q8R5M4), 
OPTN_XENLA  (Q5M7B7), TNIP2_HUMAN (Q8NFZ5), TNIP2_MOUSE (Q99JG7)
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PDB
[Detailed view]
5 PDB

2JVX; 2JVY; 2LO4; 5AAY; 5AAZ