ProRule PRU01145
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PURL: https://purl.expasy.org/prosite/rule/PRU01145
General rule information
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| Accession | PRU01145 |
| Dates | 27-JUN-2016 (Created)
19-NOV-2022 (Last updated, Version 8) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51804; ZF_C2HC_LYAR |
Name | Zinc finger C2HC LYAR-type |
| Function | Ly-1 antibody reactive clone (Lyar), which is known to be expressed abundantly in the testis, encodes a nucleolar protein that contain a LYAR- type C2HC zinc finger motif and three nuclear localization signals. |
| Scope(s) |
Eukaryota |
| Example(s) | O94311 (YH56_SCHPO); |
Propagated annotation
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Keywords
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| Metal-binding | |
| Zinc | |
| end case | |
| Zinc-finger | |
Gene Ontology
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| case <Feature:PS51804:6=[CH]> and <Feature:PS51804:9=[CH]> and <Feature:PS51804:21=[CH]> and <Feature:PS51804:25=[CH]> | |
| GO:0008270; Molecular function:zinc ion binding | |
| GO:0046872; Molecular function:metal ion binding | |
Features
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| From: PS51804 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| case <Feature:PS51804:6=C> and <Feature:PS51804:9=C> and <Feature:PS51804:21=H> and <Feature:PS51804:25=C> | ||||||||||||
| ZN_FING | from | to | /note="C2HC LYAR-type #" | |||||||||
| else case <Feature:PS51804:6=[CH]> and <Feature:PS51804:9=[CH]> and <Feature:PS51804:21=[CH]> and <Feature:PS51804:25=[CH]> | ||||||||||||
| ZN_FING | from | to | /note="C2HC LYAR-type #; atypical" | |||||||||
| else | ||||||||||||
| ZN_FING | from | to | /note="C2HC LYAR-type #; degenerate" | |||||||||
| end case | ||||||||||||
| BINDING | 6 | 6 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1" |
[CH] | 1 | |||||||
| BINDING | 9 | 9 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1" |
[CH] | 1 | |||||||
| BINDING | 21 | 21 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1" |
[CH] | 1 | |||||||
| BINDING | 25 | 25 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1" |
[CH] | 1 | |||||||
Additional information
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| Size range | 15-36 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 2 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [7] All [ 7 ]
- Retrieve set of proteins with 3D structure for this domain