PROSITE logo

PROSITE entry PS51804


View entry in original PROSITE format
View entry in raw text format (no links)
View entry auxiliary file in raw text format (no links)
Direct ScanProsite submission
General information about the entry

Entry name [info] ZF_C2HC_LYAR
Accession [info] PS51804
Entry type [info] MATRIX
Date [info] 01-JUN-2016 CREATED;
01-JUN-2016 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC51804
Associated ProRule [info] PRU01145

Name and characterization of the entry

Description [info] Zinc finger C2HC LYAR-type profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=26;
/DISJOINT: DEFINITION=PROTECT; N1=1; N2=26;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.9176445; R2=0.0071149; TEXT='-LogE';
/CUT_OFF: LEVEL=0; SCORE=1066; N_SCORE=9.5; MODE=1; TEXT='R';
/CUT_OFF: LEVEL=-1; SCORE=645; N_SCORE=6.5; MODE=1; TEXT='R?';
/DEFAULT: M0=-22; D=-100; I=-100; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255;
...
                A   C   D   E   F   G   H   I   K   L   M   N   P   Q   R   S   T   V   W   Y
/I:         B1=0; BI=-255; BD=-255;
/M: SY='M';  M= 18, 54,-24,-39,-19,  8,-38,-27,-52,-31, 98, -2,-13,-28,-50,-10,-30,-30,-53,-29;
/M: SY='V';  M= 23,-25,-38,-16,-39,-55,-14,-24,-23,-35,-34,-16,  8, -8,-43, -1, 16, 57, 21, -1;
/M: SY='W';  M=-18, 11,-46,-40, 32,-39,-17,-42, 10,-36,-18, -3,-39,-31,-14, 42, 26,  7, 45, 21;
/M: SY='F';  M=-59,-55,-40,-67, 97,-63,-42,-23,-58, 18,-25,-63,-72,-68,-62,-34,-37,  3,-36, 32;
/M: SY='S';  M=-23,-12,-36,-34,-54,-46,-17,-14,-46,-46,-40,  0,-53, 16,-45, 67, 58, -2,-72,-44;
/M: SY='C';  M=-50,146,-69,-69,-59,-59,-37,-43,-65,-41,-56,-56,-56,-71,-63,-40,-40,-53,-88,-69;
/M: SY='I';  M=-41,-39, 22, 24,-49,-40,-27, 56,-27,-10, 30, 26,-56,-33,-49,-14,-36, 18,-69,-36;
/M: SY='D';  M= -4,-59, 91,-22,-52,  0, -1,-54,-12,-59,-60,  4,-56,-16,-29,-13,-20, -9,-79,-35;
/M: SY='C';  M=-49,149,-68,-68,-59,-65,-69,-66,-64,-57,-57,-55,-79,-52,-71,-51,-36,-54,-89,-70;
/M: SY='G';  M=-29,-50,-32,-51,-24, 66, -4,-60,-41,-23, 34, 45,-57, 26,-48, 17,-38,-59,-64,-40;
/I:         I=-28; MI=0; MD=-71; IM=0; DM=-71;
/M: SY='D';  M=-14,-63, 56, 44,-55,-53,-38,-53, 39,-44,-46, 14,-52, 18,-15,-30,  5, -1,-71,-52;
/M: SY='T';  M=-22, -8, 38,-16,-45,-49,  9,-11,-46,-40, 28, -9,-56,-45,-43, 28, 50, 35,-68,-25;
/I:         I=-28; MI=0; MD=-71; IM=0; DM=-71;
/M: SY='F';  M=-53,-45,-43,-55, 89,-71,-41,  4,-52, 34,-10,-59,-70,-66,-62,-60,-50, 28,-33, -6;
/M: SY='K';  M=-35,-59, 15,-14,-52, -1,-17,-33, 59,-44,-46,-26, 14,  6,  2,-11, 32,-42, 46, -7;
/M: SY='K';  M=-40,-33,-26,-26,-66, 42,-36,-52, 74,-33,-50,-13,-37, 28, 10,-31,-48,-59,-62,-48;
/M: SY='P';  M=-19,-64, 22,  9,-33,-22,-21,-39, 32,-53,-38, 28, 53, 17,-25,-22,  8,  3,-56,-23;
/M: SY='K';  M=-10,-61, 26, 22,-64,-38,-31,-63, 54,-60,-55,  6,-51, 38,-24, 31, 21,-54,-26,-54;
/M: SY='Y';  M=-30,-60,-65,-55, -2,-68,-26, -3,-59, 26,-30,-62,-50,-57,-58,-50, -9, 55,-32, 82;
/M: SY='D';  M= -4,-65, 51, 34,-62,-49, 29,-41, 32,-43,-40, -1,-23, 31, 22,-20,-30,-28,-70,-40;
/M: SY='K';  M= 16,-33,-13,-12,-52,  9,-37,-50, 37,-51,-45, 19, 10, 33,-12, 23, -2,-34,-32, 11;
/M: SY='H';  M=-45,-39,-41,-42,-56,-59,143,-74,-46,-56,-42,-31,-58,-35,-40,-46,-45,-73,-91,-25;
/M: SY='T';  M= -8,  2,-51,-51,  6,-41,-21, -3,-18,-20, -9, 22,-58,-21, 19, -9, 57, 10,-14, 27;
/M: SY='Q';  M=-25, -2,-44,-19,-25,-23,-32,-49, 33,-45,-24, 30,-38, 60,  8, 41,-12,-43,-20, 15;
/I:         I=-11; MD=-29;
/M: SY='R';  M=-64,-58,-62,-70,-53,-59,-45,-54,-17,-81,-22,-24,-67, 17, 38,-15,-15,-58,-68,-64; D=-11;
/I:         I=-11; MI=0; MD=-29; IM=0; DM=-29;
/M: SY='C';  M=-45,148,-68,-68,-60,-57,-34,-66,-53,-57,-57,-54,-79,-63,-70,-42,-49,-54,-89,-69;
/M: SY='I';  M=-47,-65,-60,-46,-42,-34, 18, 62,-26,-31, 25,-41,  2,-39, 48,-10,-25, 13, 14, -8;
/I:         E1=0; IE=-255; DE=-255;
» more

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_04 which contains 571'864 sequence entries.


Total number of hits 14 in 7 different sequences
Number of true positive hits 14 in 7 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 2
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] ZN_FING
Feature description [info] C2HC LYAR-type
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
7 sequences

LYAR_HUMAN  (Q9NX58), LYAR_MOUSE  (Q08288), LYAR_RAT(Q6AYK5), 
UBA1C_ARATH (O64571), YC16_YEAST  (P37263), YH56_SCHPO  (O94311), 
YQ58_CAEEL  (Q09464)
» more

PDB
[Detailed view]
3 PDB

1WJV; 6ZMI; 6ZMO