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PROSITE entry PS51804


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General information about the entry

Entry name [info] ZF_C2HC_LYAR
Accession [info] PS51804
Entry type [info] MATRIX
Date [info] 01-JUN-2016 CREATED;
01-JUN-2016 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC51804
Associated ProRule [info] PRU01145

Name and characterization of the entry

Description [info] Zinc finger C2HC LYAR-type profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=26;
/DISJOINT: DEFINITION=PROTECT; N1=1; N2=26;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.9176445; R2=0.0071149; TEXT='-LogE';
/CUT_OFF: LEVEL=0; SCORE=1066; N_SCORE=9.5; MODE=1; TEXT='R';
/CUT_OFF: LEVEL=-1; SCORE=645; N_SCORE=6.5; MODE=1; TEXT='R?';
/DEFAULT: M0=-22; D=-100; I=-100; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255;
...
                A   C   D   E   F   G   H   I   K   L   M   N   P   Q   R   S   T   V   W   Y
/I:         B1=0; BI=-255; BD=-255;
/M: SY='M';  M= 18, 54,-24,-39,-19,  8,-38,-27,-52,-31, 98, -2,-13,-28,-50,-10,-30,-30,-53,-29;
/M: SY='V';  M= 23,-25,-38,-16,-39,-55,-14,-24,-23,-35,-34,-16,  8, -8,-43, -1, 16, 57, 21, -1;
/M: SY='W';  M=-18, 11,-46,-40, 32,-39,-17,-42, 10,-36,-18, -3,-39,-31,-14, 42, 26,  7, 45, 21;
/M: SY='F';  M=-59,-55,-40,-67, 97,-63,-42,-23,-58, 18,-25,-63,-72,-68,-62,-34,-37,  3,-36, 32;
/M: SY='S';  M=-23,-12,-36,-34,-54,-46,-17,-14,-46,-46,-40,  0,-53, 16,-45, 67, 58, -2,-72,-44;
/M: SY='C';  M=-50,146,-69,-69,-59,-59,-37,-43,-65,-41,-56,-56,-56,-71,-63,-40,-40,-53,-88,-69;
/M: SY='I';  M=-41,-39, 22, 24,-49,-40,-27, 56,-27,-10, 30, 26,-56,-33,-49,-14,-36, 18,-69,-36;
/M: SY='D';  M= -4,-59, 91,-22,-52,  0, -1,-54,-12,-59,-60,  4,-56,-16,-29,-13,-20, -9,-79,-35;
/M: SY='C';  M=-49,149,-68,-68,-59,-65,-69,-66,-64,-57,-57,-55,-79,-52,-71,-51,-36,-54,-89,-70;
/M: SY='G';  M=-29,-50,-32,-51,-24, 66, -4,-60,-41,-23, 34, 45,-57, 26,-48, 17,-38,-59,-64,-40;
/I:         I=-28; MI=0; MD=-71; IM=0; DM=-71;
/M: SY='D';  M=-14,-63, 56, 44,-55,-53,-38,-53, 39,-44,-46, 14,-52, 18,-15,-30,  5, -1,-71,-52;
/M: SY='T';  M=-22, -8, 38,-16,-45,-49,  9,-11,-46,-40, 28, -9,-56,-45,-43, 28, 50, 35,-68,-25;
/I:         I=-28; MI=0; MD=-71; IM=0; DM=-71;
/M: SY='F';  M=-53,-45,-43,-55, 89,-71,-41,  4,-52, 34,-10,-59,-70,-66,-62,-60,-50, 28,-33, -6;
/M: SY='K';  M=-35,-59, 15,-14,-52, -1,-17,-33, 59,-44,-46,-26, 14,  6,  2,-11, 32,-42, 46, -7;
/M: SY='K';  M=-40,-33,-26,-26,-66, 42,-36,-52, 74,-33,-50,-13,-37, 28, 10,-31,-48,-59,-62,-48;
/M: SY='P';  M=-19,-64, 22,  9,-33,-22,-21,-39, 32,-53,-38, 28, 53, 17,-25,-22,  8,  3,-56,-23;
/M: SY='K';  M=-10,-61, 26, 22,-64,-38,-31,-63, 54,-60,-55,  6,-51, 38,-24, 31, 21,-54,-26,-54;
/M: SY='Y';  M=-30,-60,-65,-55, -2,-68,-26, -3,-59, 26,-30,-62,-50,-57,-58,-50, -9, 55,-32, 82;
/M: SY='D';  M= -4,-65, 51, 34,-62,-49, 29,-41, 32,-43,-40, -1,-23, 31, 22,-20,-30,-28,-70,-40;
/M: SY='K';  M= 16,-33,-13,-12,-52,  9,-37,-50, 37,-51,-45, 19, 10, 33,-12, 23, -2,-34,-32, 11;
/M: SY='H';  M=-45,-39,-41,-42,-56,-59,143,-74,-46,-56,-42,-31,-58,-35,-40,-46,-45,-73,-91,-25;
/M: SY='T';  M= -8,  2,-51,-51,  6,-41,-21, -3,-18,-20, -9, 22,-58,-21, 19, -9, 57, 10,-14, 27;
/M: SY='Q';  M=-25, -2,-44,-19,-25,-23,-32,-49, 33,-45,-24, 30,-38, 60,  8, 41,-12,-43,-20, 15;
/I:         I=-11; MD=-29;
/M: SY='R';  M=-64,-58,-62,-70,-53,-59,-45,-54,-17,-81,-22,-24,-67, 17, 38,-15,-15,-58,-68,-64; D=-11;
/I:         I=-11; MI=0; MD=-29; IM=0; DM=-29;
/M: SY='C';  M=-45,148,-68,-68,-60,-57,-34,-66,-53,-57,-57,-54,-79,-63,-70,-42,-49,-54,-89,-69;
/M: SY='I';  M=-47,-65,-60,-46,-42,-34, 18, 62,-26,-31, 25,-41,  2,-39, 48,-10,-25, 13, 14, -8;
/I:         E1=0; IE=-255; DE=-255;
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_03 which contains 571'609 sequence entries.


Total number of hits 14 in 7 different sequences
Number of true positive hits 14 in 7 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 2
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] ZN_FING
Feature description [info] C2HC LYAR-type
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
7 sequences

LYAR_HUMAN  (Q9NX58), LYAR_MOUSE  (Q08288), LYAR_RAT(Q6AYK5), 
UBA1C_ARATH (O64571), YC16_YEAST  (P37263), YH56_SCHPO  (O94311), 
YQ58_CAEEL  (Q09464)
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PDB
[Detailed view]
3 PDB

1WJV; 6ZMI; 6ZMO