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ProRule PRU01150


General rule information [?]

PURL https://purl.expasy.org/prosite/rule/PRU01150
Accession PRU01150
Dates 5-AUG-2016 (Created)
22-NOV-2019 (Last updated, Version 3)
Data class Domain;
Predictors PROSITE; PS51808; CHCH
Name Coiled coil-helix-coiled coil-helix (CHCH) domain
Function Twin CX(9)C proteins are eukaryotic proteins that adopt a coiled coil-helix-coiled coil helix (CHCH) fold stabilized by two disulfide bonds, which are formed by the four cysteines in the twin CX(9)C motifs (i.e., two pairs of cysteines each spaced by nine residues).
Scope(s) Eukaryota
Example(s) Q5RFJ0 (COA5_PONAB);

Propagated annotation [?]

Keywords [?]

case <FTTag:disulf>
Disulfide bond
end case
Mitochondrion

Features [?]

From: PS51808
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="CHCH #"
MOTIF 4 14 /note="Cx9C motif #" C-x(9)-C
MOTIF 4 14 /note="Cx10C motif #" C-x(10)-C
MOTIF 25 35 /note="Cx9C motif #" C-x(9)-C
MOTIF 25 35 /note="Cx10C motif #" C-x(10)-C
DISULFID 4 35 disulf C-x*-C
DISULFID 14 25 disulf C-x*-C

Additional information [?]

Size range 24-67 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.



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UniProtKB rule member sequences [?]