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annotation rule: PRU01150

General rule information [?]

Accession PRU01150
Dates 5-AUG-2016 (Created)
19-DEC-2016 (Last updated, Version 2)
Data class Domain
Predictors PROSITE; PS51808; CHCH
Name Coiled coil-helix-coiled coil-helix (CHCH) domain
Function Twin CX(9)C proteins are eukaryotic proteins that adopt a coiled coil-helix-coiled coil helix (CHCH) fold stabilized by two disulfide bonds, which are formed by the four cysteines in the twin CX(9)C motifs (i.e., two pairs of cysteines each spaced by nine residues).

Propagated annotation [?]


Keywords [?]

case <FTTag:disulf>
end case


Features [?]

From: PS51808
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       CHCH #        
MOTIF     4     14       Cx9C motif #     C-x(9)-C  
MOTIF     4     14       Cx10C motif #     C-x(10)-C  
MOTIF     25     35       Cx9C motif #     C-x(9)-C  
MOTIF     25     35       Cx10C motif #     C-x(10)-C  
DISULFID     4     35           disulf   C-x*-C  
DISULFID     14     25           disulf   C-x*-C  

Additional information [?]

Size range 24-67 amino acids
Related rules None
Repeats 1
Topology Undefined
Example Q5RFJ0 (COA5_PONAB)
Scope
Eukaryota
Comments None

Copyright

PROSITE is copyright. It is produced by the SIB Swiss Institute Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified. Usage by and for commercial entities requires a license agreement. For information about the licensing scheme send an email to license@isb-sib.ch or see: prosite_license.html.



UniProtKB rule member sequences [?]