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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU01176


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU01176
General rule information [?]

Accession PRU01176
Dates 27-MAR-2017 (Created)
22-NOV-2019 (Last updated, Version 3)
Data class Domain;
Predictors PROSITE; PS51832; HD_GYP
Name HD-GYP domain
Function The HD-GYP domain is likely to be a conserved scaffold whose main role is to allow protein-protein interactions with partner GGDEF domains while achieving (a) different function(s) through diversification of the active-site cavity and the N-terminal regulatory domains.
Scope(s) Bacteria
Example(s) Q9KL18;

Propagated annotation [?]

Features [?]

From: PS51832
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="HD-GYP #"

Additional information [?]

Size range 182-222 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]