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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU01181


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU01181
General rule information [?]

Accession PRU01181
Dates 09-JUN-2017 (Created)
19-NOV-2022 (Last updated, Version 6)
Data class Domain;
Predictors PROSITE; PS51837; LITAF
Name LITAF domain
Function LITAF is a monotypic membrane protein anchored to membranes via an in-plane helical membrane anchor, present within the highly conserved C- terminal region known as the LITAF domain.
Scope(s) Eukaryota
Viruses
Ranavirus
Example(s) Q5U2U6;

Propagated annotation [?]

Comments [?]

SUBCELLULAR LOCATIONMembrane; Peripheral membrane protein.

Keywords [?]

Membrane
case <FTGroup:1>
Metal-binding
Zinc
end case

Features [?]

From: PS51837
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="LITAF"
BINDING 21 21 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"		 C 1
BINDING 24 24 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"		 C 1
BINDING 73 73 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"		 C 1
BINDING 76 76 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"		 C 1

Additional information [?]

Size range 71-98 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]