ProRule PRU01184

General rule information [?]

Accession PRU01184
Dates 20-JUL-2017 (Created)
19-NOV-2022 (Last updated, Version 6)
Data class Domain;
Predictors PROSITE; PS51839; 4FE4S_HC3
Name His(Cys)3-ligated-type [4Fe-4S] domain
Function The His(Cys)3-ligated-type [4Fe-4S] domain consists of just two alpha helices separated by a loop region that coordinates a [4Fe-4S] cluster through an unusual H-x(3)-C-x(2)-C-x(5)-C motif that includes one His and three Cys residues.
Scope(s) Bacteria
Example(s) P15690 ();

Propagated annotation [?]

Comments [?]

case <FTGroup:1>
COFACTOR Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
end case

Keywords [?]

Gene Ontology [?]

case <FTGroup:1>
GO:0051539; Molecular function:4 iron, 4 sulfur cluster binding
GO:0005506; Molecular function:iron ion binding

Cross-references [?]

PROSITE PS00642; COMPLEX1_75K_2; 0-1;

Features [?]

From: PS51839
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="4Fe-4S His(Cys)3-ligated-type #"
BINDING 17 17 /ligand="[4Fe-4S] cluster"
H 1
BINDING 19 19 /ligand="[4Fe-4S] cluster"
H 1
BINDING 21 21 /ligand="[4Fe-4S] cluster"
C 1
BINDING 24 24 /ligand="[4Fe-4S] cluster"
C 1
BINDING 30 30 /ligand="[4Fe-4S] cluster"
C 1

Additional information [?]

Size range 30-51 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined


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UniProtKB rule member sequences [?]