General rule information
[?]
Accession |
PRU01184 |
Dates |
20-JUL-2017 (Created) 19-NOV-2022 (Last updated, Version 6) |
Predictors |
PROSITE; PS51839; 4FE4S_HC3
|
Name |
His(Cys)3-ligated-type [4Fe-4S] domain |
Function |
The His(Cys)3-ligated-type [4Fe-4S] domain consists of just two alpha helices separated by a loop region that coordinates a [4Fe-4S] cluster through an unusual H-x(3)-C-x(2)-C-x(5)-C motif that includes one His and three Cys residues. |
Propagated annotation
[?]
case <FTGroup:1>
end case
PROSITE |
PS00642; COMPLEX1_75K_2; 0-1; |
case <FTGroup:1>
GO:0051539; Molecular function: 4 iron, 4 sulfur cluster binding.
GO:0005506; Molecular function: iron ion binding.
end case
From: PS51839 |
Key
|
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From
|
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To
|
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Description
|
|
Tag
|
|
Condition
|
|
FTGroup
|
DOMAIN
|
|
from
|
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to
|
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4Fe-4S His(Cys)3-ligated-type #
|
|
|
|
|
|
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BINDING
|
|
17
|
|
17
|
|
/ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883" /ligand_label="#1
|
|
|
|
H
|
|
1
|
BINDING
|
|
19
|
|
19
|
|
/ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883" /ligand_label="#1
|
|
|
|
H
|
|
1
|
BINDING
|
|
21
|
|
21
|
|
/ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883" /ligand_label="#1
|
|
|
|
C
|
|
1
|
BINDING
|
|
24
|
|
24
|
|
/ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883" /ligand_label="#1
|
|
|
|
C
|
|
1
|
BINDING
|
|
30
|
|
30
|
|
/ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883" /ligand_label="#1
|
|
|
|
C
|
|
1
|
Additional information
[?]
Size range |
30-51 amino acids |
Related rules |
None |
Repeats |
1 |
Topology |
Undefined |
Example |
P15690 (NDUS1_BOVIN) |
Scope |
Bacteria
Eukaryota |
Comments |
None |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and
distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives
(CC BY-NC-ND 4.0) License, see
prosite_license.html.
UniProtKB rule member sequences
[?]