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annotation rule: PRU01184

General rule information [?]

Accession PRU01184
Dates 20-JUL-2017 (Created)
22-NOV-2019 (Last updated, Version 3)
Data class Domain
Predictors PROSITE; PS51839; 4FE4S_HC3
Name His(Cys)3-ligated-type [4Fe-4S] domain
Function The His(Cys)3-ligated-type [4Fe-4S] domain consists of just two alpha helices separated by a loop region that coordinates a [4Fe-4S] cluster through an unusual H-x(3)-C-x(2)-C-x(5)-C motif that includes one His and three Cys residues.

Propagated annotation [?]

Comments [?]

case <FTGroup:1>
Cofactor [4Fe-4S] cluster
end case

Cross-references [?]

PROSITE PS00642; COMPLEX1_75K_2; 0-1;

Gene Ontology [?]

case <FTGroup:1>
GO:0051539; Molecular function: 4 iron, 4 sulfur cluster binding.
GO:0005506; Molecular function: iron ion binding.

Keywords [?]

end case

Features [?]

From: PS51839
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       4Fe-4S His(Cys)3-ligated-type #        
METAL     17     17       Iron-sulfur #1 (4Fe-4S); via tele nitrogen     H   1
METAL     19     19       Iron-sulfur #1 (4Fe-4S); via tele nitrogen     H   1
METAL     21     21       Iron-sulfur #1 (4Fe-4S)     C   1
METAL     24     24       Iron-sulfur #1 (4Fe-4S)     C   1
METAL     30     30       Iron-sulfur #1 (4Fe-4S)     C   1

Additional information [?]

Size range 30-51 amino acids
Related rules None
Repeats 1
Topology Undefined
Example P15690 (NDUS1_BOVIN)
Comments None


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UniProtKB rule member sequences [?]