PROSITE entry PS51839
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General information about the entry
Entry name [info] | 4FE4S_HC3 |
Accession [info] | PS51839 |
Entry type [info] | MATRIX |
Date [info] |
27-SEP-2017 CREATED;
26-FEB-2020 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
PROSITE Doc. [info] | PDOC51839 |
Associated ProRule [info] | PRU01184 |
Name and characterization of the entry
Description [info] | His(Cys)3-ligated-type [4Fe-4S] domain profile. |
Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=40; /DISJOINT: DEFINITION=PROTECT; N1=5; N2=36; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.8934792; R2=0.0111744; TEXT='-LogE'; /NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=2196.2661133; R2=1.4897637; PRIORITY=1; TEXT='Heuristic 5.0%'; /CUT_OFF: LEVEL=0; SCORE=592; H_SCORE=3078; N_SCORE=8.5; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=413; H_SCORE=2812; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: M0=-9; D=-50; I=-50; B1=-500; E1=-500; MI=-105; MD=-105; IM=-105; DM=-105; ... A B C D E F G H I K L M N P Q R S T V W Y Z /I: B1=0; BI=-105; BD=-105; /M: SY='E'; M= -6, 1,-26, 5, 15,-22,-19, -8,-16, 6,-12, -9, -4,-11, 3, 4, -5, -7,-12,-26,-14, 8; /M: SY='V'; M= 5,-23,-13,-26,-22, -3,-23,-24, 17,-20, 12, 6,-22,-24,-21,-19, -6, 1, 26,-27,-10,-22; /M: SY='K'; M=-10, 0,-26, 0, 6,-23,-18, -6,-20, 22,-19, -9, 3,-15, 7, 19, -6, -7,-15,-25,-11, 6; /M: SY='E'; M= -5, 10,-26, 13, 22,-28,-15, -5,-26, 15,-23,-16, 6, -9, 9, 7, 1, -6,-21,-28,-16, 15; /M: SY='A'; M= 13,-15,-17,-23,-14, 5,-15,-15, -3,-10, -2, 0,-12,-17,-13,-13, -3, -3, 0,-13, -1,-13; /M: SY='R'; M=-16, -9,-30,-10, 3,-24,-22, 0,-19, 19,-16, -4, -2,-17, 21, 44, -8,-10,-18,-20, -9, 8; /M: SY='K'; M= -5, -1,-26, 0, 14,-27,-18, -3,-23, 22,-22,-10, -1,-10, 12, 13, -2, -5,-17,-24,-12, 12; /M: SY='S'; M= 3, -1,-19, -1, 8,-24, 6,-12,-23, -6,-22,-16, 2,-11, -2,-10, 9, -2,-18,-29,-21, 2; /M: SY='V'; M= 1,-22,-19,-26,-20, -7,-20,-21, 14,-12, 6, 8,-18,-22,-16,-10,-11, -6, 19,-23, -9,-20; /M: SY='M'; M= -8,-27,-19,-31,-24, 3,-28,-17, 26,-21, 26, 31,-25,-25,-16,-18,-21, -8, 22,-22, -2,-20; /M: SY='E'; M= -7, 16,-27, 26, 38,-31,-15, -3,-30, 7,-23,-21, 5, -4, 11, -2, 4, -7,-26,-32,-19, 25; /M: SY='F'; M=-12,-22,-25,-25,-14, 13,-24,-14, -4,-11, 9, 3,-18,-24,-10, -1,-19,-11, -7, 3, 6,-11; /M: SY='L'; M=-10,-28,-22,-31,-21, 6,-31,-21, 25,-28, 39, 20,-26,-26,-17,-21,-25, -8, 13,-20, -1,-20; /M: SY='L'; M=-11,-29,-20,-31,-21, 14,-29,-17, 18,-27, 42, 24,-28,-29,-19,-19,-28,-10, 9,-18, 2,-19; /M: SY='T'; M= 2, -4,-20, -5, -1,-14,-13,-13, -6,-11, -7, -6, -6,-14, -7,-14, 2, 3, -2,-25, -9, -5; /M: SY='N'; M=-11, 25,-24, 16, 8,-22,-10, 2,-17, 4,-24,-16, 33,-15, 2, -1, 3, -4,-23,-34,-17, 5; /M: SY='H'; M=-18, -1,-30, -1, -2,-21,-13, 91,-31,-11,-21, -2, 9,-20, 8, -2, -9,-20,-30,-29, 16, -2; /M: SY='P'; M=-10,-11,-34, -6, 6,-25,-19,-12,-16, -7,-20,-10,-11, 52, -4,-14, -9, -9,-24,-29,-23, -2; /M: SY='H'; M=-10,-18,-23,-20,-13, 4,-25, 18, -2,-19, 17, 9,-14,-25,-11,-12,-19,-13, -5,-20, 8,-13; /M: SY='D'; M=-13, 24,-27, 33, 7,-21,-13, 2,-27, 2,-23,-20, 11,-15, -1, -6, -1, -7,-22,-23, 1, 2; /M: SY='C'; M=-10,-20,120,-30,-30,-20,-30,-30,-30,-30,-20,-20,-20,-40,-30,-30,-10,-10,-10,-50,-30,-30; /M: SY='P'; M= -7,-17,-30,-13, -7,-20,-13,-20,-14,-14,-14,-12,-16, 41,-13,-18, -6, 1,-18,-27,-21,-13; /M: SY='V'; M= -4,-24,-18,-27,-23, 0,-28,-25, 20,-20, 4, 6,-21,-13,-22,-20, -7, 2, 25,-26, -8,-23; /M: SY='C'; M=-10,-20,120,-30,-30,-20,-30,-30,-30,-30,-20,-20,-20,-40,-30,-30,-10,-10,-10,-50,-30,-30; /M: SY='D'; M= -9, 30,-27, 40, 28,-33,-11, -1,-32, 2,-25,-24, 15, -8, 6, -7, 2, -8,-27,-35,-20, 17; /M: SY='E'; M=-10, -1,-29, 0, 17,-20,-20, 2,-22, 16,-19, -9, -2,-12, 17, 13, -6, -9,-22,-15, 2, 16; /I: I=-5; MI=0; MD=-10; IM=0; DM=-10; /M: SY='G'; M= -4, 5,-25, -1, -9,-25, 30, -9,-31, -5,-29,-19, 17,-18, -8, -2, 6, -9,-26,-28,-23, -9; /I: I=-15; MI=0; MD=-32; IM=0; DM=-32; /M: SY='G'; M= 2, -8,-29, -8,-11,-29, 57,-18,-37,-16,-28,-19, -1,-17,-15,-18, 1,-18,-28,-21,-28,-13; /M: SY='E'; M= -9, 16,-26, 16, 18,-26, -7, 6,-28, 5,-24,-18, 18,-12, 6, 6, 2, -7,-26,-32,-17, 11; /M: SY='C'; M=-10,-20,120,-30,-30,-20,-30,-30,-30,-30,-20,-20,-20,-40,-30,-30,-10,-10,-10,-50,-30,-30; /M: SY='E'; M=-13, 13,-30, 21, 33,-30,-18, 18,-30, 3,-22,-16, 5, -2, 15, -2, -2,-10,-29,-31,-12, 23; /M: SY='L'; M=-11,-30,-22,-33,-23, 15,-32,-22, 23,-30, 41, 18,-27,-28,-22,-22,-27,-10, 12,-17, 3,-23; /M: SY='Q'; M=-12, -3,-29, -3, 12,-31,-21, 25,-18, 2,-13, 2, -1,-14, 42, 5, -5,-12,-26,-22, -3, 26; /M: SY='D'; M= -9, 30,-25, 31, 13,-29, -9, -1,-28, 7,-27,-21, 24,-12, 2, -1, 3, -4,-25,-34,-18, 7; /M: SY='M'; M= -4,-16,-20,-21,-12, -9,-23,-12, 9,-11, 8, 16,-14,-18, 0, -9, -8, 2, 5,-22, -6, -7; /M: SY='T'; M= 11,-12, -7,-19,-16,-12, -9,-19, -3,-13, -6, 0,-10,-17,-14,-16, 6, 13, 7,-27,-14,-15; /M: SY='M'; M=-10,-11,-23,-11, -7, -5,-25, -9, 7, -8, 2, 10,-14,-20, -8,-11,-12, -8, 7,-19, 3, -9; /M: SY='K'; M= 0, -8,-23,-10, 3,-16,-13, -6,-11, 6, -9, 6, -8,-14, 4, 2, -5, -7, -9,-20, -8, 3; /M: SY='Y'; M=-10,-21,-23,-26,-22, 14,-25, -9, 6,-17, 3, 5,-19,-25,-17,-15,-14, -3, 5, 10, 21,-20; /M: SY='G'; M= -4, -3,-30, -1, -9,-30, 44,-16,-37, -5,-29,-19, 2,-17,-12,-10, -1,-16,-28,-22,-25,-11; /I: E1=0; IE=-105; DE=-105;» more |
Numerical results [info]
Total number of hits | 65 in 65 different sequences |
Number of true positive hits | 65 in 65 different sequences |
Number of 'unknown' hits | 0 |
Number of false positive hits | 0 |
Number of false negative sequences | 0 |
Number of 'partial' sequences | 0 |
Precision (true positives / (true positives + false positives)) | 100.00 % |
Recall (true positives / (true positives + false negatives)) | 100.00 % |
Comments [info]
Taxonomic range [info] | Eukaryotes, Prokaryotes (Bacteria) |
Maximum number of repetitions [info] | 1 |
Matrix type [info] | protein_domain |
Scaling database [info] | reversed |
Author [info] | CJA_Sigrist |
Feature key [info] | DOMAIN |
Feature description [info] | 4Fe-4S His(Cys)3-ligated-type |
Version [info] | 3 |
Cross-references [info]
UniProtKB/Swiss-Prot True positive sequences |
65 sequences
FDHL_BACSU (Q795Y4), FDHL_STAA3 (Q2FEI5), FDHL_STAA8 (Q2FVV9), FDHL_STAAB (Q2YYT1), FDHL_STAAC (Q5HDP9), FDHL_STAAM (Q931G2), FDHL_STAAN (Q99RW4), FDHL_STAAR (Q6GEC4), FDHL_STAAS (Q6G711), FDHL_STAAW (Q7A057), FDHL_STAHJ (Q4L8G8), FDHL_STAS1 (Q49ZN0), HNDD_SOLFR (Q46508), HOXU_CUPNH (P22318), HYDA_THEMA (O52683), NDUS1_ACACA (Q37373), NDUS1_ARATH (Q9FGI6), NDUS1_BOVIN (P15690), NDUS1_CANAL (A0A1D8PU51), NDUS1_DICCI (Q2LCP5), NDUS1_DICDI (Q34312), NDUS1_DROME (Q94511), NDUS1_GORGO (Q0MQG1), NDUS1_HUMAN (P28331), NDUS1_MACFA (Q4R6K9), NDUS1_MOUSE (Q91VD9), NDUS1_NEUCR (P24918), NDUS1_PANTR (Q0MQG2), NDUS1_PONAB (P0CB67), NDUS1_PONPY (P0CB68), NDUS1_RAT (Q66HF1), NDUS1_RECAM (O21241), NDUS1_SOLTU (Q43644), NQO3_PARDE (P29915), NQO3_THET8 (Q56223), NUOG2_RHIME (P56914), NUOG_BLOFL (Q7VRV7), NUOG_BUCAI (P57257), NUOG_BUCAP (Q8K9Y2), NUOG_BUCBP (Q89AU1), NUOG_ECO57 (Q8XCX2), NUOG_ECOL6 (Q8FFJ9), NUOG_ECOLI (P33602), NUOG_MYCBO (P59962), NUOG_MYCTO (P9WIV8), NUOG_MYCTU (P9WIV9), NUOG_PSEAE (Q9I0J6), NUOG_PSEFL (Q9KGW3), NUOG_PSEPK (Q88FH2), NUOG_PSESM (Q87ZQ4), NUOG_RICBR (Q1RKD2), NUOG_RICCN (Q92G92), NUOG_RICFE (Q4UK22), NUOG_RICPR (Q9ZCF6), NUOG_RICTY (Q68VV2), NUOG_SALTI (P0A1Y5), NUOG_SALTY (P0A1Y4), NUOG_SHEON (Q8EI34), NUOG_SHIFL (Q7UC56), NUOG_STRCO (Q9XAR0), NUOG_YERPE (Q8ZDL2), PHF1_CLOPA (P29166), SFRA_GEOSK (D7AF63), SFRA_GEOSL (Q74FU6), YJGC_BACSU (O34720)» more
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PDB [Detailed view] |
161 PDB
1C4A; 1C4C; 1FEH; 2FUG; 2YBB; 3C8Y; 3I9V; 3IAM; 3IAS; 3M9S; 4HEA; 4XDC; 4XDD; 5BYQ; 5BYR; 5BYS; 5LA3; 5LC5; 5LDW; 5LDX; 5O31; 5OEF; 5XTB; 5XTD; 5XTH; 5XTI; 6G2J; 6G72; 6GLY; 6GLZ; 6GM0; 6GM1; 6GM2; 6GM3; 6GM4; 6GM8; 6H63; 6I0D; 6I1P; 6N59; 6N6P; 6NAC; 6Q8O; 6Q8W; 6Q8X; 6Y11; 6YF4; 6ZIY; 6ZJL; 6ZJN; 6ZJY; 6ZR2; 6ZTQ; 7A23; 7A24; 7AK5; 7AK6; 7AQR; 7AR7; 7AR8; 7ARB; 7AWT; 7B93; 7DGQ; 7DGR; 7DGS; 7DGZ; 7DH0; 7DKF; 7NYR; 7NYU; 7NYV; 7NZ1; 7P5H; 7P61; 7P62; 7P63; 7P64; 7P69; 7P7C; 7P7E; 7P7J; 7P7K; 7P7L; 7P7M; 7P8N; 7P91; 7P92; 7PSA; 7QHF; 7QSD; 7QSK; 7QSL; 7QSM; 7QSN; 7QSO; 7R41; 7R42; 7R43; 7R44; 7R45; 7R46; 7R47; 7R48; 7R4C; 7R4D; 7R4F; 7R4G; 7Z7R; 7Z7S; 7Z7T; 7Z7V; 7Z80; 7Z83; 7Z84; 7ZC5; 7ZCI; 8AIO; 8AJ6; 8ALN; 8AP2; 8B9Z; 8BA0; 8BED; 8BPX; 8BQ5; 8BQ6; 8C2S; 8CA3; 8CA4; 8CA5; 8CJY; 8ESW; 8ESZ; 8OLT; 8OM1; 8PVM; 8PW5; 8PW6; 8PW7; 8Q0A; 8Q0F; 8Q0J; 8Q0M; 8Q0O; 8Q0Q; 8Q1P; 8Q1U; 8Q1Y; 8Q25; 8Q45; 8Q46; 8Q47; 8Q48; 8Q49; 8Q4A; 8QM3; 8RGP; 8RGQ; 8RGR; 8RGT » more |