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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU01188


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU01188
General rule information [?]

Accession PRU01188
Dates 01-SEP-2017 (Created)
22-NOV-2019 (Last updated, Version 3)
Data class Domain;
Predictors PROSITE; PS51842; IF_ROD_2
Name Intermediate filament (IF) rod domain
Function IF proteins have a very strong tendency to dimerize via the formation of an alpha-helical coiled coil (CC) by their rod domains.
Scope(s) Eukaryota
Example(s) Q9D646;

Propagated annotation [?]

Comments [?]

SIMILARITYBelongs to the intermediate filament family.

Keywords [?]

Coiled coil
Intermediate filament

Gene Ontology [?]

GO:0005198; Molecular function:structural molecule activity

Cross-references [?]

PROSITE PS00226; IF_ROD_1; 1;

Features [?]

From: PS51842
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="IF rod #"

Additional information [?]

Size range 13-467 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]