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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU01209


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU01209
General rule information [?]

Accession PRU01209
Dates 24-APR-2018 (Created)
22-NOV-2019 (Last updated, Version 3)
Data class Domain;
Predictors PROSITE; PS51862; BSPN_CSAB
Name BetaSPN-type cysteine-stabilized alpha/beta (CS-alpha/beta) domain
Function The betaSPN-type CS-alpha/beta has K(+) channel blocking activity.
Scope(s) Eukaryota
Scorpiones
Example(s) Q0GY40;

Propagated annotation [?]

Comments [?]

TISSUE SPECIFICITYExpressed by the venom gland.

Keywords [?]

case <FTTag:disulf>
Disulfide bond
end case
Toxin

Gene Ontology [?]

GO:0090729; Molecular function:toxin activity

Features [?]

From: PS51862
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="BetaSPN-type CS-alpha/beta #"
DISULFID 4 24 disulf C-x*-C
DISULFID 11 29 disulf C-x*-C
DISULFID 15 31 disulf C-x*-C

Additional information [?]

Size range 30-45 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]