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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU01212


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU01212
General rule information [?]

Accession PRU01212
Dates 25-JUN-2018 (Created)
22-NOV-2019 (Last updated, Version 3)
Data class Domain;
Predictors PROSITE; PS51865; PDZ_GRASP
Name GRASP-type PDZ domain
Function Essentially all GRASPs contain a conserved N-terminal GRASP region, which comprises two tandem PDZ domains (PDZ1 and PDZ2), a classical protein- peptide interaction domain, and is responsible for GRASP homo-oligomerization and for the attachment to the Golgi membrane.
Scope(s) Eukaryota
Example(s) Q04410;

Propagated annotation [?]

Comments [?]

SUBCELLULAR LOCATIONGolgi apparatus membrane.

Keywords [?]

Golgi apparatus
Membrane

Gene Ontology [?]

GO:0007030; Biological process:Golgi organization
GO:0005794; Cellular component:Golgi apparatus

Features [?]

From: PS51865
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="PDZ GRASP-type #"

Additional information [?]

Size range 80-125 amino acids
Related rules None
Fusion None
Repeats 2
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]