We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
ProRule PRU01214
View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU01214
General rule information
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| Accession | PRU01214 |
| Dates | 29-JUN-2018 (Created)
22-NOV-2019 (Last updated, Version 4) |
| Data class | Domain; |
| Predictors |
Metamotif; -; PS51865~PS51865 |
Name | GRASP region |
| Function | Essentially all GRASPs contain a conserved N-terminal GRASP region, which comprises two tandem PDZ domains (PDZ1 and PDZ2), a classical protein- peptide interaction domain, and is responsible for GRASP homo-oligomerization and for the attachment to the Golgi membrane. |
| Scope(s) |
Eukaryota |
| Example(s) | Q9BQQ3; |
Propagated annotation
[?]
Cross-references
[?]
| PROSITE | PS51865; PDZ_GRASP; 2; |
Features
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| From: PS51865~PS51865 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| REGION | from | to+16 | /note="GRASP #" | |||||||||
Additional information
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| Size range | 175-230 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1-2 |
| Topology | Cytoplasmic |
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