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ProRule PRU01220


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PURL: https://purl.expasy.org/prosite/rule/PRU01220
General rule information [?]

Accession PRU01220
Dates 24-AUG-2018 (Created)
19-NOV-2022 (Last updated, Version )
Data class Domain;
Predictors PROSITE; PS51872; ZF_ZBR
Name Zinc finger ZBR-type
Function The ZBR-type zinc finger is an autonomously folded domain with a central, twisted, four-stranded beta-sheet and two zinc ions on opposite ends of the sheet.
Scope(s) Eukaryota
Euteleostomi
Example(s) Q66H04;

Propagated annotation [?]

Keywords [?]

Metal-binding
Zinc
end case
Zinc-finger

Gene Ontology [?]

case (<Feature:PS51872:5=[CH]> and <Feature:PS51872:8=[CH]> and <Feature:PS51872:23=[CH]> and <Feature:PS51872:28=[CH]>) or (<Feature:PS51872:33=[CH]> and <Feature:PS51872:36=[CH]> and <Feature:PS51872:41=[CH]> and <Feature:PS51872:46=[CH]>)
GO:0046872; Molecular function:metal ion binding

Features [?]

From: PS51872
Key From To Description Tag Condition FTGroup
case (<Feature:PS51872:5=[C]> and <Feature:PS51872:8=[C]> and <Feature:PS51872:23=[C]> and <Feature:PS51872:28=[C]>) and (<Feature:PS51872:33=[C]> and <Feature:PS51872:36=[C]> and <Feature:PS51872:41=[H]> and <Feature:PS51872:46=[C]>)
ZN_FING from to /note="ZBR-type #"
else case (<Feature:PS51872:5=[CH]> and <Feature:PS51872:8=[CH]> and <Feature:PS51872:23=[CH]> and <Feature:PS51872:28=[CH]>) and (<Feature:PS51872:33=[CH]> and <Feature:PS51872:36=[CH]> and <Feature:PS51872:41=[CH]> and <Feature:PS51872:46=[CH]>)
ZN_FING from to /note="ZBR-type #; atypical"
else
ZN_FING from to /note="ZBR-type #; degenerate"
end case
BINDING 5 5 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"		 [CH] 1
BINDING 8 8 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"		 [CH] 1
BINDING 23 23 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"		 [CH] 1
BINDING 28 28 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"		 [CH] 1
BINDING 33 33 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#2"		 [CH] 2
BINDING 36 36 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#2"		 [CH] 2
BINDING 41 41 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#2"		 [CH] 2
BINDING 46 46 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#2"		 [CH] 2

Additional information [?]

Size range 45-55 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]