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PRU01220


General rule information [?]

Accession PRU01220
Dates 24-AUG-2018 (Created)
19-NOV-2022 (Last updated, Version 5)
Data class Domain
Predictors PROSITE; PS51872; ZF_ZBR
Name Zinc finger ZBR-type
Function The ZBR-type zinc finger is an autonomously folded domain with a central, twisted, four-stranded beta-sheet and two zinc ions on opposite ends of the sheet.

Propagated annotation [?]


Gene Ontology [?]

case (<Feature:PS51872:5=[CH]> and <Feature:PS51872:8=[CH]> and <Feature:PS51872:23=[CH]> and <Feature:PS51872:28=[CH]>) or (<Feature:PS51872:33=[CH]> and <Feature:PS51872:36=[CH]> and <Feature:PS51872:41=[CH]> and <Feature:PS51872:46=[CH]>)
GO:0046872; Molecular function: metal ion binding.

Keywords [?]

Metal-binding
Zinc
end case

Zinc-finger

Features [?]

case (<Feature:PS51872:5=[C]> and <Feature:PS51872:8=[C]> and <Feature:PS51872:23=[C]> and <Feature:PS51872:28=[C]>) and (<Feature:PS51872:33=[C]> and <Feature:PS51872:36=[C]> and <Feature:PS51872:41=[H]> and <Feature:PS51872:46=[C]>)
From: PS51872
Key     From     To       Description   Tag   Condition   FTGroup
ZN_FING     from     to       ZBR-type #        
else case (<Feature:PS51872:5=[CH]> and <Feature:PS51872:8=[CH]> and <Feature:PS51872:23=[CH]> and <Feature:PS51872:28=[CH]>) and (<Feature:PS51872:33=[CH]> and <Feature:PS51872:36=[CH]> and <Feature:PS51872:41=[CH]> and <Feature:PS51872:46=[CH]>)
ZN_FING     from     to       ZBR-type #; atypical        
else
ZN_FING     from     to       ZBR-type #; degenerate        
end case

BINDING     5     5       /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1     [CH]   1
BINDING     8     8       /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1     [CH]   1
BINDING     23     23       /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1     [CH]   1
BINDING     28     28       /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1     [CH]   1
BINDING     33     33       /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#2     [CH]   2
BINDING     36     36       /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#2     [CH]   2
BINDING     41     41       /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#2     [CH]   2
BINDING     46     46       /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#2     [CH]   2

Additional information [?]

Size range 45-55 amino acids
Related rules None
Repeats 1
Topology Undefined
Example Q66H04 (FBX43_RAT)
Scope
Eukaryota; Euteleostomi
Comments None

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.


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UniProtKB rule member sequences [?]