PRU01223
General rule information
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Accession | PRU01223 |
Dates | 12-OCT-2018 (Created) 22-NOV-2019 (Last updated, Version 6) |
Data class | Domain |
Predictors | PROSITE; PS51875; HAV_P48_PRO |
Names | Hypovirulence-associated virus (HAV) papain-like protease p48 domain; Peptidase C8 domain |
Function | The HAV papain-like protease p48 is a cysteine protease, which forms the peptidase family C8. A Cys and a His catalytic residue are essential for autocatalytic cleavage between the cleavage site residues Gly and Ala located at the C-terminus of the domain. |
Propagated annotation
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Description
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case <FTGroup:1>
+ Contains: RecName: Full=Papain-like protease p48; EC 3.4.22.-; |
Comments
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Function | Papain-like protease p48 is a cysteine protease of the peptidase family C8. |
Gene Ontology
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GO:0008234; Molecular function: cysteine-type peptidase activity.
Keywords
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end case
Features
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From: PS51875 | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
DOMAIN | from | to | Peptidase C8 # | |||||||||
ACT_SITE | 71 | 71 | For papain-like protease p48 activity | C | 1 | |||||||
ACT_SITE | 118 | 118 | For papain-like protease p48 activity | H | 1 | |||||||
SITE | to | to+1 | Cleavage; by papain-like protease p48 | G-A |
Additional information
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Size range | 130-140 amino acids |
Related rules | None |
Repeats | 1 |
Topology | Undefined |
Example | Q9YTU2 (POLB_CHPVU) |
Scope | Viruses; Hypovirus |
Comments | None |
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UniProtKB rule member sequences
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