Home  |  Contact
annotation rule: PRU01223

General rule information [?]

Accession PRU01223
Dates 12-OCT-2018 (Created)
22-NOV-2019 (Last updated, Version 6)
Data class Domain
Predictors PROSITE; PS51875; HAV_P48_PRO
Names Hypovirulence-associated virus (HAV) papain-like protease p48 domain; Peptidase C8 domain
Function The HAV papain-like protease p48 is a cysteine protease, which forms the peptidase family C8. A Cys and a His catalytic residue are essential for autocatalytic cleavage between the cleavage site residues Gly and Ala located at the C-terminus of the domain.

Propagated annotation [?]


Description [?]

case <FTGroup:1>
+ Contains: RecName: Full=Papain-like protease p48; EC 3.4.22.-;

Comments [?]

Function Papain-like protease p48 is a cysteine protease of the peptidase family C8.

Gene Ontology [?]

GO:0008234; Molecular function: cysteine-type peptidase activity.

Keywords [?]

end case


Features [?]

From: PS51875
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       Peptidase C8 #        
ACT_SITE     71     71       For papain-like protease p48 activity     C   1
ACT_SITE     118     118       For papain-like protease p48 activity     H   1
SITE     to     to+1       Cleavage; by papain-like protease p48     G-A  

Additional information [?]

Size range 130-140 amino acids
Related rules None
Repeats 1
Topology Undefined
Example Q9YTU2 (POLB_CHPVU)
Scope
Viruses; Hypovirus
Comments None

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.



UniProtKB rule member sequences [?]

UniProtKB/Swiss-Prot sets
Viruses [2]