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annotation rule: PRU01236

General rule information [?]

Accession PRU01236
Dates 28-MAR-2019 (Created)
22-NOV-2019 (Last updated, Version 3)
Data class Domain
Predictors PROSITE; PS51888; CLIP
Name Clip domain
Function Although the functions of clip domains are not completely clear, the clip domain in arthropods has been demonstrated to act in the regulation of proteinase activity, protein-protein interaction and bactericidal activities.

Propagated annotation [?]

Comments [?]

Domain The clip domain consists of 35-55 residues which are 'knitted' together usually by 3 conserved disulfide bonds forming a clip-like compact structure.
Similarity Belongs to the peptidase S1 family. CLIP subfamily.

Keywords [?]

case <FTTag:disulf>
end case

Features [?]

From: PS51888
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       Clip #        
DISULFID     2     52           disulf   C-x*-C  
DISULFID     12     42           disulf   C-x*-C  
DISULFID     18     53           disulf   C-x*-C  

Additional information [?]

Size range 40-65 amino acids
Related rules None
Repeats 1
Topology Undefined
Example Q9VB68 (GRASS_DROME)
Eukaryota; Arthropoda
Comments None


PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]