ProRule PRU01236

General rule information [?]

Accession PRU01236
Dates 28-MAR-2019 (Created)
22-NOV-2019 (Last updated, Version 3)
Data class Domain;
Predictors PROSITE; PS51888; CLIP
Name Clip domain
Function Although the functions of clip domains are not completely clear, the clip domain in arthropods has been demonstrated to act in the regulation of proteinase activity, protein-protein interaction and bactericidal activities.
Scope(s) Eukaryota
Example(s) Q9VB68 (GRASS_DROME);

Propagated annotation [?]

Comments [?]

DOMAINThe clip domain consists of 35-55 residues which are 'knitted' together usually by 3 conserved disulfide bonds forming a clip-like compact structure.
SIMILARITYBelongs to the peptidase S1 family. CLIP subfamily.

Keywords [?]

case <FTTag:disulf>
Disulfide bond
end case

Features [?]

From: PS51888
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="Clip #"
DISULFID 2 52 disulf C-x*-C
DISULFID 12 42 disulf C-x*-C
DISULFID 18 53 disulf C-x*-C

Additional information [?]

Size range 40-65 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined


PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

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UniProtKB rule member sequences [?]