We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
ProRule PRU01243
View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU01243
General rule information
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| Accession | PRU01243 |
| Dates | 20-MAY-2019 (Created)
22-NOV-2019 (Last updated, Version 3) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51895; AA1 |
Name | Alt a 1 (AA1)-like domain |
| Function | AA1-like proteins are fungal toxins that can induce plant defense responses and cell death. They may contribute to virulence by protecting the cell wall, thus allowing fungal growth to be maintained and preventing the recognition of degraded beta-1,3-glucan by the plant. AA1 proteins comprise ~150 amino acids and contain two pairs of highly conserved disulfide bonds. |
| Scope(s) |
Eukaryota Pezizomycotina |
| Example(s) | Q5EZ82; |
Propagated annotation
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Keywords
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| case <FTTag:disulf> | |
| Disulfide bond | |
| end case | |
Features
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| From: PS51895 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="AA1-like" | |||||||||
| DISULFID | 40 | 55 | disulf | C-x*-C | ||||||||
| DISULFID | 97 | 109 | disulf | C-x*-C | ||||||||
Additional information
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| Size range | 105-125 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [5] All [ 5 ]
- Retrieve set of proteins with 3D structure for this domain