ProRule PRU01244

General rule information [?]

Accession PRU01244
Dates 5-JUN-2019 (Created)
22-NOV-2019 (Last updated, Version 4)
Data class Domain;
Predictors PROSITE; PS51896; ZF_C4H2
Name Zinc finger C4H2-type
Function ZC4H2, which belongs to a conserved gene family found in all metazoans, plays an important role during embryonic development of the central and peripheral nervous systems. The ZC4H2 gene encodes a zinc-finger protein with a C-terminal domain, which includes a putative C4H2 zinc-finger characterized by four cysteine residues and two histidine residues, and a coiled-coil domain.
Scope(s) Eukaryota
Example(s) Q68FG0 (ZC4H2_MOUSE);

Propagated annotation [?]

Keywords [?]

Gene Ontology [?]

case <Feature:PS51896:9=[CH]> and <Feature:PS51896:12=[CH]> and <Feature:PS51896:13=[CH]> and <Feature:PS51896:17=[CH]> and <Feature:PS51896:33=[CH]> and <Feature:PS51896:26=[CH]>
GO:0046872; Molecular function:metal ion binding

Features [?]

From: PS51896
Key From To Description Tag Condition FTGroup
case <Feature:PS51896:9=C> and <Feature:PS51896:12=C> and <Feature:PS51896:13=H> and <Feature:PS51896:17=H> and <Feature:PS51896:23=C> and <Feature:PS51896:26=C>
ZN_FING 9 26 /note="C4H2-type #"
else case <Feature:PS51896:9=[CH]> and <Feature:PS51896:12=[CH]> and <Feature:PS51896:13=[CH]> and <Feature:PS51896:17=[CH]> and <Feature:PS51896:33=[CH]> and <Feature:PS51896:26=[CH]>
ZN_FING 9 26 /note="C4H2-type #; atypical"
ZN_FING 9 26 /note="C4H2-type #; degenerate"
end case

Additional information [?]

Size range 40-45 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined


PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

View rule in raw text format (no links)

UniProtKB rule member sequences [?]