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ProRule PRU01244


General rule information [?]

PURL https://purl.expasy.org/prosite/rule/PRU01244
Accession PRU01244
Dates 5-JUN-2019 (Created)
22-NOV-2019 (Last updated, Version 4)
Data class Domain;
Predictors PROSITE; PS51896; ZF_C4H2
Name Zinc finger C4H2-type
Function ZC4H2, which belongs to a conserved gene family found in all metazoans, plays an important role during embryonic development of the central and peripheral nervous systems. The ZC4H2 gene encodes a zinc-finger protein with a C-terminal domain, which includes a putative C4H2 zinc-finger characterized by four cysteine residues and two histidine residues, and a coiled-coil domain.
Scope(s) Eukaryota
Metazoa
Example(s) Q68FG0 (ZC4H2_MOUSE);

Propagated annotation [?]

Keywords [?]

Metal-binding
Zinc
Zinc-finger
end case

Gene Ontology [?]

case <Feature:PS51896:9=[CH]> and <Feature:PS51896:12=[CH]> and <Feature:PS51896:13=[CH]> and <Feature:PS51896:17=[CH]> and <Feature:PS51896:33=[CH]> and <Feature:PS51896:26=[CH]>
GO:0046872; Molecular function:metal ion binding

Features [?]

From: PS51896
Key From To Description Tag Condition FTGroup
case <Feature:PS51896:9=C> and <Feature:PS51896:12=C> and <Feature:PS51896:13=H> and <Feature:PS51896:17=H> and <Feature:PS51896:23=C> and <Feature:PS51896:26=C>
ZN_FING 9 26 /note="C4H2-type #"
else case <Feature:PS51896:9=[CH]> and <Feature:PS51896:12=[CH]> and <Feature:PS51896:13=[CH]> and <Feature:PS51896:17=[CH]> and <Feature:PS51896:33=[CH]> and <Feature:PS51896:26=[CH]>
ZN_FING 9 26 /note="C4H2-type #; atypical"
else
ZN_FING 9 26 /note="C4H2-type #; degenerate"
end case

Additional information [?]

Size range 40-45 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

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UniProtKB rule member sequences [?]