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annotation rule: PRU01244

General rule information [?]

Accession PRU01244
Dates 5-JUN-2019 (Created)
22-NOV-2019 (Last updated, Version 4)
Data class Domain
Predictors PROSITE; PS51896; ZF_C4H2
Name Zinc finger C4H2-type
Function ZC4H2, which belongs to a conserved gene family found in all metazoans, plays an important role during embryonic development of the central and peripheral nervous systems. The ZC4H2 gene encodes a zinc-finger protein with a C-terminal domain, which includes a putative C4H2 zinc-finger characterized by four cysteine residues and two histidine residues, and a coiled-coil domain.

Propagated annotation [?]


Gene Ontology [?]

case <Feature:PS51896:9=[CH]> and <Feature:PS51896:12=[CH]> and <Feature:PS51896:13=[CH]> and <Feature:PS51896:17=[CH]> and <Feature:PS51896:33=[CH]> and <Feature:PS51896:26=[CH]>
GO:0046872; Molecular function: metal ion binding.

Keywords [?]

end case


Features [?]

case <Feature:PS51896:9=C> and <Feature:PS51896:12=C> and <Feature:PS51896:13=H> and <Feature:PS51896:17=H> and <Feature:PS51896:23=C> and <Feature:PS51896:26=C>
From: PS51896
Key     From     To       Description   Tag   Condition   FTGroup
ZN_FING     9     26       C4H2-type #        
else case <Feature:PS51896:9=[CH]> and <Feature:PS51896:12=[CH]> and <Feature:PS51896:13=[CH]> and <Feature:PS51896:17=[CH]> and <Feature:PS51896:33=[CH]> and <Feature:PS51896:26=[CH]>
ZN_FING     9     26       C4H2-type #; atypical        
else
ZN_FING     9     26       C4H2-type #; degenerate        
end case


Additional information [?]

Size range 40-45 amino acids
Related rules None
Repeats 1
Topology Undefined
Example Q68FG0 (ZC4H2_MOUSE)
Scope
Eukaryota; Metazoa
Comments None

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.



UniProtKB rule member sequences [?]

UniProtKB/Swiss-Prot sets
Eukaryota [3]