PROSITE entry PS51896
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General information about the entry
| PURL [info] | https://purl.expasy.org/prosite/signature/PS51896 |
| Entry name [info] | ZF_C4H2 |
| Accession [info] | PS51896 |
| Entry type [info] | MATRIX |
| Date [info] |
31-JUL-2019 CREATED;
07-APR-2021 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC51896 |
| Associated ProRule [info] | PRU01244 |
Name and characterization of the entry
| Description [info] | Zinc finger C4H2-type profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=43; /DISJOINT: DEFINITION=PROTECT; N1=5; N2=39; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.4182392; R2=0.0067978; TEXT='-LogE'; /NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=4984.5571289; R2=5.5880079; PRIORITY=1; TEXT='Heuristic 5.0%'; /CUT_OFF: LEVEL=0; SCORE=1336; H_SCORE=12450; N_SCORE=10.5; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=748; H_SCORE=9164; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: M0=-6; D=-50; I=-50; B1=-500; E1=-500; MI=-105; MD=-105; IM=-105; DM=-105; ... A B C D E F G H I K L M N P Q R S T V W Y Z /I: B1=0; BI=-105; BD=-105; /M: SY='H'; M= 3,-16,-27,-16, -4,-15,-26, 24, 2,-12, -6, 1,-14,-12, 19, 5,-10, -1, 0,-27, 0, 4; /M: SY='Q'; M= 6,-14,-20,-21, 1,-19,-16, -7, 10, -7, -5, -3, -6,-11, 43, 8,-10, 0, -4,-17,-10, 14; /M: SY='P'; M= -5,-15,-28, -8, 8,-33, -8, 5,-25, 8,-28,-35,-23, 80, -2,-10, 2, 5,-33,-30,-20, -2; /M: SY='P'; M= -3,-20,-26,-17, 3,-33,-14, 14,-15, 14,-11, -3,-19, 54, -4, -6,-14, 0,-25,-30,-16, -4; /M: SY='P'; M= 9,-13,-30, -6, 6,-33, -6, -1,-19, 6,-23,-21,-19, 65, 4,-10, -3, 4,-21,-37,-27, 0; /M: SY='M'; M= -1,-24,-24,-37,-21, 25,-24, 1, 6, 9, 20, 30, -4,-40,-17, -4,-16, -7, 4,-15, 5,-21; /M: SY='Q'; M= 4, -4,-26, -4, 20,-17,-14,-13,-20, 25,-20, 9, -4, 6, 30, 17, -4, -6,-24,-16,-10, 21; /M: SY='E'; M= 13, 0,-11, 1, 17,-26,-12,-11,-13, 5, -9, -5, -1, 0, 8,-15, 14, 11, -8,-32,-22, 14; /M: SY='C'; M=-30,-20,170,-30, 10,-30,-40,-50,-20,-30, 0,-20,-10,-30,-20,-20,-20,-20,-20,-20,-60, 0; /M: SY='G'; M= -1, -6,-20,-10, -6,-11, 17,-15, -1,-11, 3, -2,-10,-15, 5, -8,-10, -7,-15, -6, -2, -1; /M: SY='N'; M= 6, 15,-16, 4, -4,-10, 0,-10, -6, 0,-20,-13, 30,-17,-10,-14, 25, 16,-14,-45,-27,-10; /M: SY='C'; M=-30,-20,170,-30, 10,-30,-40,-50,-20,-30, 0,-20,-10,-30,-20,-20,-20,-20,-20,-20,-60, 0; /M: SY='H'; M=-25,-22,-52,-18, -5,-15,-30,105,-18,-18, 0, 13,-17, 3, -2, -8,-12,-18,-20,-25, 22, -5; /M: SY='Q'; M= 6, 9,-16, -3, 9,-23,-13, -4,-13, 0,-20, -6, 23,-11, 47, 11, -6, 4,-26,-32,-21, 21; /M: SY='Q'; M= 6, 9,-16, -3, 9,-23,-13, -4,-13, 0,-20, -6, 23,-11, 47, 11, -6, 4,-26,-32,-21, 21; /M: SY='I'; M= 0,-20,-20,-40,-30, 0,-10,-20, 60,-20, 20, 10, 0,-30,-20,-30,-10, 0, 40,-30,-10,-30; /M: SY='H'; M=-20,-20,-50,-20, 0,-30,-30,140,-20,-20,-10, 20,-10, 10, 0,-10,-10,-20,-30,-50, 0, 0; /M: SY='R'; M=-10,-16,-13,-10,-10, 1,-20,-10,-11, -1, 2, 7,-20,-17, 11, 43,-14,-19, -3, -7, 11, -4; /M: SY='N'; M= 0, 40,-10, 10,-10,-10, 0,-10, 0, 0,-20, 0, 80,-30,-10,-20, 0, 10,-20,-70,-40,-10; /M: SY='A'; M= 40, 0,-30, 0, 0,-20, 0,-20, 0, 0,-10, 10, 0,-10, 10,-10, 10, 10, 10,-50,-40, 0; /M: SY='P'; M=-10,-20,-30,-10, 10,-40,-10, 10,-30, 10,-30,-40,-30,110, 0,-10,-10, 0,-40,-30,-20, 0; /M: SY='I'; M= 4,-20,-20,-33,-30, 4,-17,-24, 53,-20, 16, 6, -7,-34,-24,-23,-10, 4, 44,-30, -3,-30; /M: SY='C'; M=-30,-20,170,-30, 10,-30,-40,-50,-20,-30, 0,-20,-10,-30,-20,-20,-20,-20,-20,-20,-60, 0; /M: SY='P'; M= -3,-13,-26,-10, -1,-33,-14, -1,-19, 3,-19,-25,-15, 69, 0,-17, 1, 19,-21,-37,-16, -4; /M: SY='H'; M= -9,-16,-24,-19, -6, -9,-24, 53, 3,-10, 16, 30,-11,-18,-10,-11,-16, -7, -7,-34, 9, -6; /M: SY='C'; M=-30,-20,170,-30, 10,-30,-40,-50,-20,-30, 0,-20,-10,-30,-20,-20,-20,-20,-20,-20,-60, 0; /M: SY='K'; M= 15, 0,-30, 0, 13,-14, -6,-20,-13, 25,-16, 16, 0, 3, 4, 3, 4, -3, -9,-31,-21, 6; /M: SY='A'; M= 33, 0,-28, 0, 0,-18, 0,-18, -2, 0,-12, 3, 0,-10, 5,-10, 17, 12, 5,-45,-35, -2; /M: SY='K'; M= 0, 0,-30, 0, 20,-10,-10,-20,-20, 40,-20, 20, 0, 10, 0, 10, 0,-10,-20,-20,-10, 10; /M: SY='S'; M= 10, -7,-20,-11, -4,-14, -7, 1, -3, 7, -5, 10, 0,-21,-10, -6, 18, 13, -6,-30,-16,-10; /M: SY='R'; M= -6,-20,-20,-21,-17, -6,-16,-14, 3, -1, -5, 4,-13,-17, 11, 39,-10,-19, 9,-11, -4,-11; /M: SY='S'; M= 21, 0,-24, 0, 0,-14, 0,-14, -6, 0,-16, -9, 0,-10, -3,-10, 29, 16, -3,-37,-27, -6; /M: SY='R'; M= -4, 7,-19, 0, -3,-10,-10,-12,-16, 14,-20, 5, 22,-12, 8, 25, -4,-10,-16,-31,-17, -1; /M: SY='N'; M= 0, 40,-10, 10,-10,-10, 0,-10, 0, 0,-20, 0, 80,-30,-10,-20, 0, 10,-20,-70,-40,-10; /M: SY='P'; M= 9,-13,-30, -6, 6,-33, -6, -1,-19, 6,-23,-21,-19, 65, 4,-10, -3, 4,-21,-37,-27, 0; /M: SY='K'; M= 0, 0,-30, 0, 20,-10,-10,-20,-20, 40,-20, 20, 0, 10, 0, 10, 0,-10,-20,-20,-10, 10; /M: SY='N'; M= 0, 15,-23, 4, 9,-10, -6,-16,-13, 25,-20, 13, 30, -5, -4, -1, 0, -3,-20,-39,-21, 3; /M: SY='P'; M= -6,-13,-34,-10, -1,-36, 23, -5,-23, 3,-26,-33,-19, 65, -7,-14, -6, -7,-36,-15,-24, -7; /M: SY='K'; M= 15, 0,-30, 0, 13,-14, -6,-20,-13, 25,-16, 16, 0, 3, 4, 3, 4, -3, -9,-31,-21, 6; /M: SY='R'; M= -5, 6,-18, -1, -5,-10,-11,-12,-17, 11,-20, 3, 21,-14, 10, 31, -5,-12,-15,-29,-17, -2; /M: SY='K'; M= 4, 0,-26, 0, 13,-10, -6,-16,-16, 25,-20, 5, 0, 3, -4, 3, 15, 1,-16,-24,-14, 3; /M: SY='D'; M= 17, 10,-21, 22, 17,-33,-10,-12,-19, 3,-12, -8, -1, -4, 21, -2, 2, -2,-13,-32,-23, 17; /M: SY='Q'; M= 10, 3,-30, 12, 10,-32,-15, 15,-19, -3,-14, -4, -3, -3, 30, 5, -3, -3,-18,-33,-16, 15; /I: E1=0; IE=-105; DE=-105;» more |
Numerical results [info]
| Total number of hits | 3 in 3 different sequences |
| Number of true positive hits | 3 in 3 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 0 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 100.00 % |
Comments [info]
| Taxonomic range [info] | Eukaryotes |
| Maximum number of repetitions [info] | 1 |
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | CJA_Sigrist |
| Feature key [info] | ZN_FING |
| Feature description [info] | C4H2-type |
| Version [info] | 3 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
3 sequences
ZC4H2_DANRE (Q7T3I0), ZC4H2_HUMAN (Q9NQZ6), ZC4H2_MOUSE (Q68FG0)
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