PRU01245
General rule information
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| Accession | PRU01245 |
| Dates | 19-JUN-2019 (Created) 22-NOV-2019 (Last updated, Version 4) |
| Data class | Domain |
| Predictors | PROSITE; PS51897; ANNEXIN_2 |
| Name | Annexin repeat |
| Function | Annexins are a group of calcium-binding proteins that associate reversibly with membranes. Each of these proteins consist of a unique N- terminal domain followed by four or eight copies (in annexin A6) of a conserved segment of approximately 70 residues. Each of the repeats has the potential to have a type II Ca(2+)-binding bipartite motif, located on two different alpha-helices (GxGT-(38-40 residues)-D/E), but typically some of them are non-functional. |
Propagated annotation
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Cross-references
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| PROSITE | PS00223; ANNEXIN_1; 4-8; |
Comments
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| Similarity | Belongs to the annexin family. |
Gene Ontology
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GO:0005509; Molecular function: calcium ion binding.
GO:0005544; Molecular function: calcium-dependent phospholipid binding.
GO:0005544; Molecular function: calcium-dependent phospholipid binding.
Keywords
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Features
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| From: PS51897 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| REPEAT | from | to | Annexin # | |||||||||
Additional information
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| Size range | 60-80 amino acids |
| Related rules | None |
| Repeats | 4-8 |
| Topology | Undefined |
| Example | P09525 (ANXA4_HUMAN) |
| Scope | Eukaryota |
| Comments | None |
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UniProtKB rule member sequences
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UniProtKB/Swiss-Prot sets
Eukaryota [101]
- Retrieve set of proteins with 3D structure for this domain