We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
ProRule PRU01252
View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU01252
General rule information
[?]
| Accession | PRU01252 |
| Dates | 30-AUG-2019 (Created)
22-NOV-2019 (Last updated, Version 3) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51904; GLYCOSYL_HYDROL_F25_2 |
Name | Chalaropsis (Ch)-type lyzozyme domain |
| Function | The Ch-type lysozymes family GH25 domain exhibits both beta-1,4-N- acetylmuramidase and beta-1,4-N,6-O-diacetylmuramidase activities and its evolutionary spread is diverse, comprising bacterial, viral (mainly phage) and eukaryotic representatives. |
| Scope(s) |
Eukaryota Bacteria Viruses |
| Example(s) | P34020; |
Propagated annotation
[?]
Comments
[?]
| SIMILARITY | Belongs to the glycosyl hydrolase 25 family. |
Keywords
[?]
Gene Ontology
[?]
| case <FTGroup:1> | |
| GO:0003824; Molecular function:catalytic activity | |
| GO:0019835; Biological process:cytolysis | |
| GO:0042742; Biological process:defense response to bacterium | |
| GO:0016798; Molecular function:hydrolase activity, acting on glycosyl bonds | |
| GO:0008152; Biological process:metabolic process | |
| GO:0016787; Molecular function:hydrolase activity | |
| GO:0003796; Molecular function:lysozyme activity | |
| GO:0009253; Biological process:peptidoglycan catabolic process | |
| GO:0016998; Biological process:cell wall macromolecule catabolic process | |
Cross-references
[?]
| PROSITE | PS00953; GLYCOSYL_HYDROL_F25_1; 1; |
Features
[?]
| From: PS51904 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="Ch-type lysozyme #" | |||||||||
| ACT_SITE | 6 | 6 | D | 1 | ||||||||
| ACT_SITE | 94 | 94 | D | 1 | ||||||||
| ACT_SITE | 96 | 96 | E | 1 | ||||||||
Additional information
[?]
| Size range | 190-230 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
[?]
- UniProtKB/Swiss-Prot sets
Bacteria [6] Eukaryota [14] Viruses [5] All [ 25 ]
- Retrieve set of proteins with 3D structure for this domain