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PRU01253


General rule information [?]

Accession PRU01253
Dates 18-SEP-2019 (Created)
19-NOV-2022 (Last updated, Version 6)
Data class Domain
Predictors PROSITE; PS51905; ZF_UBZ1
Name Zinc finger UBZ1-type
Function The ubiquitin-binding zinc finger (UBZ) is a type of zinc- coordinating beta-beta-alpha fold domain found mainly in proteins involved in DNA repair and transcriptional regulation. UBZ domains coordinate a zinc ion with cysteine or histidine residues; depending on their amino acid sequence, UBZ domains are classified into several families. Type 1 UBZs are CCHH-type zinc fingers found in tandem UBZ domains of TAX1-binding protein 1 (TAX1BP1).

Propagated annotation [?]


Keywords [?]

Zinc-finger
case <Feature:PS51905:4=[CH]> and <Feature:PS51905:7=[CH]> and <Feature:PS51905:23=[CH]> and <Feature:PS51905:27=[CH]>
Zinc
Metal-binding
end case


Features [?]

case <Feature:PS51905:4=C> and <Feature:PS51905:7=C> and <Feature:PS51905:23=H> and <Feature:PS51905:27=H>
From: PS51905
Key     From     To       Description   Tag   Condition   FTGroup
ZN_FING     from     to       UBZ1-type #        
else case <Feature:PS51905:4=[CH]> and <Feature:PS51905:7=[CH]> and <Feature:PS51905:23=[CH]> and <Feature:PS51905:27=[CH]>
ZN_FING     from     to       UBZ1-type #; atypical        
else
ZN_FING     from     to       UBZ1-type #; degenerate        
end case

BINDING     4     4       /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1     [CH]   1
BINDING     7     7       /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1     [CH]   1
BINDING     23     23       /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1     [CH]   1
BINDING     27     27       /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1     [CH]   1

Additional information [?]

Size range 20-30 amino acids
Related rules None
Repeats 1-2
Topology Undefined
Example Q9V9Y9 (SPNF_DROME)
Scope
Eukaryota; Metazoa
Comments None

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.


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UniProtKB rule member sequences [?]