General rule information
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Accession |
PRU01253 |
Dates |
18-SEP-2019 (Created) 19-NOV-2022 (Last updated, Version 6) |
Predictors |
PROSITE; PS51905; ZF_UBZ1
|
Name |
Zinc finger UBZ1-type |
Function |
The ubiquitin-binding zinc finger (UBZ) is a type of zinc- coordinating beta-beta-alpha fold domain found mainly in proteins involved in DNA repair and transcriptional regulation. UBZ domains coordinate a zinc ion with cysteine or histidine residues; depending on their amino acid sequence, UBZ domains are classified into several families. Type 1 UBZs are CCHH-type zinc fingers found in tandem UBZ domains of TAX1-binding protein 1 (TAX1BP1). |
Propagated annotation
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case <Feature:PS51905:4=[CH]> and <Feature:PS51905:7=[CH]> and <Feature:PS51905:23=[CH]> and <Feature:PS51905:27=[CH]>
end case
case <Feature:PS51905:4=C> and <Feature:PS51905:7=C> and <Feature:PS51905:23=H> and <Feature:PS51905:27=H>
From: PS51905 |
Key
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From
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To
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Description
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Tag
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Condition
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FTGroup
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ZN_FING
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from
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to
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UBZ1-type #
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else case <Feature:PS51905:4=[CH]> and <Feature:PS51905:7=[CH]> and <Feature:PS51905:23=[CH]> and <Feature:PS51905:27=[CH]>
ZN_FING
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from
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to
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UBZ1-type #; atypical
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else
ZN_FING
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from
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to
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UBZ1-type #; degenerate
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end case
BINDING
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4
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4
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/ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1
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[CH]
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1
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BINDING
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7
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7
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/ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1
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[CH]
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1
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BINDING
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23
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23
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/ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1
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|
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[CH]
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1
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BINDING
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27
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27
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/ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1
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[CH]
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1
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Additional information
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Size range |
20-30 amino acids |
Related rules |
None |
Repeats |
1-2 |
Topology |
Undefined |
Example |
Q9V9Y9 (SPNF_DROME) |
Scope |
Eukaryota; Metazoa |
Comments |
None |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and
distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives
(CC BY-NC-ND 4.0) License, see
prosite_license.html.
UniProtKB rule member sequences
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