PRU01255
General rule information
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Accession | PRU01255 |
Dates | 19-SEP-2019 (Created) 19-NOV-2022 (Last updated, Version 8) |
Data class | Domain |
Predictors | PROSITE; PS51907; ZF_UBZ3 |
Name | Zinc finger UBZ3-type |
Function | The ubiquitin-binding zinc finger (UBZ) is a type of zinc- coordinating beta-beta-alpha fold domain found mainly in proteins involved in DNA repair and transcriptional regulation. UBZ domains coordinate a zinc ion with cysteine or histidine residues; depending on their amino acid sequence, UBZ domains are classified into several families. Type 3 UBZs are CCHH-type zinc fingers found only in the Y-family translesion polymerase eta. |
Propagated annotation
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Comments
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Similarity | Belongs to the DNA polymerase type-Y family. |
Gene Ontology
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GO:0042276; Biological process: error-prone translesion synthesis.
GO:0035861; Cellular component: site of double-strand break.
GO:0009314; Biological process: response to radiation.
GO:0035861; Cellular component: site of double-strand break.
GO:0009314; Biological process: response to radiation.
case <Feature:PS51907:8=[CH]> and <Feature:PS51907:11=[CH]> and <Feature:PS51907:23=[CH]> and <Feature:PS51907:27=[CH]>
GO:0046872; Molecular function: metal ion binding.
Keywords
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end case
Features
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case <Feature:PS51907:8=C> and <Feature:PS51907:11=C> and <Feature:PS51907:23=H> and <Feature:PS51907:27=H>
From: PS51907 | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
ZN_FING | from | to | UBZ3-type # |
else case <Feature:PS51907:8=[CH]> and <Feature:PS51907:11=[CH]> and <Feature:PS51907:23=[CH]> and <Feature:PS51907:27=[CH]>
else
end case
Additional information
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Size range | 30-40 amino acids |
Related rules | None |
Repeats | 1 |
Topology | Undefined |
Example | Q9Y253 (POLH_HUMAN) |
Scope | Eukaryota |
Comments | None |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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-
UniProtKB/Swiss-Prot sets
Eukaryota [6]
- Retrieve set of proteins with 3D structure for this domain