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PROSITE entry PS51907


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General information about the entry

Entry name [info] ZF_UBZ3
Accession [info] PS51907
Entry type [info] MATRIX
Date [info] 13-NOV-2019 CREATED;
03-AUG-2022 DATA UPDATE;
27-MAR-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC51905
Associated ProRule [info] PRU01255

Name and characterization of the entry

Description [info] Zinc finger UBZ3-type profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=35;
/DISJOINT: DEFINITION=PROTECT; N1=4; N2=32;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.7665536; R2=0.0088976; TEXT='-LogE';
/CUT_OFF: LEVEL=0; SCORE=1094; N_SCORE=12.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=420; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-76; D=-100; I=-100; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255;
...
                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-255; BD=-255;
/M: SY='S';  M=   9, -41,  26,  15, -25, -39,  24, -55, -15, -28, -72, -11,  18,  23, -59,  38,  17,   5, -24, -43;
/M: SY='W';  M=   1, -62,  25,  16, -46, -24, -17, -41,  -5, -22, -28,  11,  29,  30, -67,  26,   7, -16,  64, -53;
/M: SY='E';  M=   1,-221,  10,  46, -31, -10, -44,  27, -53, -13, -48, -23,  17,  -9, -34,  12,   0,   9, -58, -27;
/M: SY='D';  M= -16, -58,  67,  21, -32, -27, -39, -70,  -5, -22, -60,  19,  39, -11, -36,  -2,  19, -35, -51, -68;
/M: SY='T';  M= -22, -11,  14, -30, -16,  -8,  19, -45, -22,  -5,  23, -13, -17,  18, -27,  16,  56, -23,  26, -14;
/M: SY='Y';  M= -75,-102, -41,   4,  44,-225, -21,   9, -17,   7, -40, -41,-129,  -1, -66, -81, -24,  16,  22,  92;
/M: SY='T';  M= -41, -28, -55, -10,  12,-112,  -8,   8,  35,   3, -23, -25,   1,  10,  12,  -8,  42,   7,-221, -15;
/M: SY='C';  M=-208, 161,-228,-228,-218,-224, -35,-226,-224,-216,-216,-214,-239,-231,-230,-211,-208,-213,-248,-228;
/I:         I=-28; MD=-71;
/M: SY='P';  M= -15,-121,  59,  45,-105, -66, -30,-109, -16,-104,-217,  -9,  63, -31,-102,  48,  -3, -77,-232,-218; D=-28;
/I:         I=-28; MD=-71;
/M: SY='R';  M= -89,-121,   9,  48,-120,-221, -27,  -9,  42, -30,-128, -63, -23,  46,  71, -90, -27, -77,-224, -60; D=-28;
/I:         I=-28; MI=-71; IM=-71; DM=-71;
/M: SY='C';  M=-208, 162,-228,-228,-219,-224,-228,-225,-224,-216,-216,-214,-239,-232,-231,-211,-208,-213,-248,-229;
/M: SY='G';  M= -86,-222,   6, -62,-226,  73,  34,-230,  33,-227, -81,  56, -92,  15, -14,   0, -73,-226,-226, -54;
/M: SY='K';  M=  25,-124, -59,  29, -52,-121, -48,   0,  61, -36,  -4, -35, -63,  53, -22,   5, -15, -37,-222, -51;
/M: SY='S';  M= -20, -74, -22,  24, -17, -98,   5, -42,   7, -20,  36,  21,  -6,  21,  21,  36,  13, -26, -33,  -2;
/M: SY='I';  M=-210,-121,-231,-227,  49,-233,-224,  77,-223,  30,  13,-131, -84,-222,-102, -72,-113,  51,-216, -90;
/M: SY='P';  M=   6,-224,  15,  19, -70, -61,  -1, -78, -10,   4, -65, -35,  88, -26, -73,  21,  -5, -87,-226, -99;
/M: SY='V';  M= -10, -13,  25,  30, -17, -60, -57,  13, -34,  -7,  -6, -19,  30, -22, -33,  20, -12,  32, -53,-210;
/M: SY='W';  M=   1, -40,  38,  32, -42, -53,  39, -91, -43, -40, -64,  -9,   2,   1, -65,  23,  28, -43,  97, -37;
/I:         I=-19; MD=-47;
/M: SY='E';  M= -24,-118,  58,  73,   6, -53, -63,-161,  14, -52, -26, -24, -72,  17, -30, -12, -41, -26, -71, -62; D=-19;
/I:         I=-19; MI=0; MD=-47; IM=0; DM=-47;
/M: SY='M';  M= -67,-221,-146, -47,  41,-142, -60,   5,  13,  36,  73,-215,-223,  -4,  40, -97,-104,   7,  -5,  25;
/M: SY='Q';  M=  -7,-226,  17,  10,-225, -24, -65, -64, -55, -25, -35, -22,  59,  96, -41, -21, -11, -53,-225,-214;
/M: SY='E';  M= -86, -57,-100, 109,-227,-217,-202,-107, -56, -78,-217, -33,-205, -24,-200,  31,  -5,-105,-228,-218;
/M: SY='H';  M=-217,-228,-200,-201,-215,-218, 160,-233,-205,-216,-201,-190,-217,-194,-199,-206,-215,-233,-251,-184;
/M: SY='Q';  M= -11, -39,  21,  27, -89,-154, -63, -55,   5,  21,  38,  26,-215,  49,  -8,  30,  -1, -48,-226,-210;
/M: SY='D';  M=-215,-228, 128,-179,-234,-211,-200,-232, -82, -97,-229, -50,-214,-201,-210,-203,-204,-229,-250,-217;
/M: SY='W';  M=-130,-230,-228,-106,  79,-128,  33, -78, -98, -96,-203,-223,-229,-103,-115,-219,-218,-212, 132,  99;
/M: SY='H';  M=-217,-228,-200,-201,-215,-218, 160,-233,-205,-216,-201,-190,-217,-194,-199,-206,-215,-233,-251,-184;
/M: SY='F';  M= -25,-217,-230,-108,  93,-228,-214, -10,-222,  30,  33,-223,-228,-117,-221,-217, -69,  41,-202,  33;
/M: SY='A';  M= 108,-209,-215,-207,-222,-197,-216,-210,-210, -85,-207, -68,-214,-206,-214, -84,-199, -59,-223,-218;
/M: SY='K';  M= -57, -55,-144,  13, -72,-221, -35, -41,  66,  39,  51,-207,-217,  58,   7, -56,-100, -27,-221,-207;
/M: SY='D';  M= -55,-225,  84,  43,-228,-106, -21,-227,  40,-166, -23,  14,-212,  12,  29,   5, -69,-223,-233,-215;
/M: SY='L';  M=-213,-217,-102,-224,-189,-233,-217,  16,-225,  95,  -2,-229,-230,-218,-222,-224,-209, -32,-219, -96;
/M: SY='Q';  M= -14,-223, -33,   0,-114,-106,  26, -95, -76,-147, -74, -26,-213, 112, -41,  55,-201, -74,-222, -14;
/M: SY='Q';  M=  -4,-118,  31,  48,-144, -94, -13, -70,  42, -58, -65,  21,-213,  56,  40,  -1, -46,-107, -69,-213;
/M: SY='E';  M= -42,-224, -22,  82,-228, -39,-108,-226,  -6,-153, -66, -17, -67,  72, -19,  45, -69,-221,-226, -99;
/I:         E1=0; IE=-255; DE=-255;
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Post-processing [info]

COMPETES_HIT_WITH PS50157; PS51801; PS51905; PS51906; PS51908

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_02 which contains 571'282 sequence entries.


Total number of hits 7 in 6 different sequences
Number of true positive hits 7 in 6 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 2
Feature key [info] ZN_FING
Feature description [info] UBZ3-type
Version [info] 4

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
6 sequences

ESO1_SCHPO  (O42917), POLH_DROME  (Q9VNX1), POLH_HUMAN  (Q9Y253), 
POLH_MOUSE  (Q9JJN0), POLH_YEAST  (Q04049), POLK_ARATH  (Q6JDV7)
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PDB
[Detailed view]
2 PDB

2I5O; 3WUP