PROSITE entry PS51908
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General information about the entry
| PURL [info] | https://purl.expasy.org/prosite/signature/PS51908 |
| Entry name [info] | ZF_UBZ4 |
| Accession [info] | PS51908 |
| Entry type [info] | MATRIX |
| Date [info] |
13-NOV-2019 CREATED;
07-APR-2021 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC51905 |
| Associated ProRule [info] | PRU01256 |
Name and characterization of the entry
| Description [info] | Zinc finger UBZ4-type profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=28; /DISJOINT: DEFINITION=PROTECT; N1=3; N2=26; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.5569990; R2=0.0071366; TEXT='-LogE'; /NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=2649.1757812; R2=0.5597523; PRIORITY=1; TEXT='Heuristic 5.0%'; /CUT_OFF: LEVEL=0; SCORE=1184; H_SCORE=3312; N_SCORE=11.0; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=553; H_SCORE=2959; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: M0=-34; D=-100; I=-100; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255; ... A C D E F G H I K L M N P Q R S T V W Y /I: B1=0; BI=-255; BD=-255; /M: SY='K'; M= -24, -84, 12, -66, -72, -5, 14, 1, 41, 32, 30, -68, -81, 35, -14, -32, 7, -15, 16, -69; /M: SY='V'; M= -10, -80, -88, -82, 17, -4, -86, 1, 1, 21, -55, -82, 1, -80, -25, -75, -67, 73, -86, -68; /M: SY='Q'; M= 22, -14, -4, 3, 5, -76, 5, 2, -30, -41, -68, -6, 35, 52, -71, 17, 2, -20, -81, 26; /M: SY='C'; M= -72, 156, -92, -92, -82, -87, -92, -89, -87, -80, -80, -78,-103, -95, -94, -74, -72, -76,-112, -93; /M: SY='P'; M= -75,-101, -76, -64, -96, -78, -78, -84, -72, -94, -80, -81, 126, 13, -83, -22, -69, -89, -89, -92; /M: SY='I'; M= -45, -81, -89, -86, -62, -91, -87, 68, -84, 21, 9, -22, -86, -81, -86, 2, -15, 61, -90, -69; /M: SY='C'; M= -72, 156, -92, -92, -82, -87, -92, -89, -87, -80, -80, -78,-103, -95, -94, -74, -72, -76,-112, -93; /M: SY='Q'; M= -9, -85, -10, -20, 6, 42, 10, -83, -64, -22, -73, 48, -80, 79, -68, 18, -67, -82, -86, -72; /M: SY='K'; M= -41, -86, -37, 19, -82, -39, -69, -2, 55, -46, 37, -13, -77, 54, 32, -65, 29, -12, -87, -74; /M: SY='M'; M= -42, -16, 7, 26, -27, -41, -12, -71, 14, -8, 57, 41, 38, -63, 18, -22, 5, -16, -90, -74; /M: SY='F'; M= -74, -82, -92, -84, 69, -92, -77, 16, -81, 19, 68, -85, -89, 25, -81, -80, -70, 48, -72, 11; /M: SY='P'; M= -67, -86, -68, 30, -10, -42, -73, -78, 11, -14, -7, -21, 79, -64, -29, 54, -11, -51, -88, -77; /M: SY='E'; M= 14, -9, -67, 37, -27, -10, 22, -37, -30, 17, 13, 16, 18, -64, 14, 4, 16, -70, -89, -73; /M: SY='S'; M= 16, -80, -3, 12, -70, -75, -68, -35, -31, 16, 28, 25, -79, -13, -6, 33, 32, -38, -83, 31; /M: SY='D'; M= 0, -83, 43, -5, -26, -77, 38, -31, 33, 12, -67, 10, -79, 33, -64, 18, -23, -14, -89, -20; /M: SY='I'; M= -72, -83, -26, -86, -57, -7, -81, 66, -85, 43, -49, -83, -88, -81, -86, -13, -69, 34, -79, 35; /I: I=-26; MI=0; MD=-65; IM=0; DM=-65; /M: SY='N'; M= -73, -84, -18, 36, -8, -21, -2, -7, -3, -83, -76, 92, -79, -14, 33, -61, -5, -80, -93, -75; /M: SY='W'; M= -67, 3, -33, 15, -81, -39, -71, -15, 7, -80, -74, -65, -5, 58, 38, 42, 20, -20, 74, -71; /M: SY='H'; M= -80, -92, -64, -64, -78, -82, 151, -97, -69, -79, -64, -53, -80, -58, -63, -69, -78, -96,-114, -47; /M: SY='L'; M= -5, 10, -93, -86, -58, -92, -83, 15, -86, 65, 38, -89, -90, -82, -85, -80, -69, 52, -87, -68; /M: SY='D'; M= -37, -87, 105, -49, -4, -74, -63, -86, -9, -84, 35, 48, -79, -65, -71, -65, -67, -86,-102, -75; /I: I=-30; MI=0; MD=-77; IM=0; DM=-77; /M: SY='E'; M= -69, -86, -1, 49, -71, -80, -67, 8, -37, -44, -22, -25, -78, 22, 30, 34, 13, -8, 25, 45; /M: SY='C'; M= -72, 154, -90, -90, -82, -87, 12, -89, -87, -79, -79, -77,-101, -93, -92, -74, -72, -77,-112, -90; /M: SY='L'; M= 9, -80, -81, -79, -60, -42, -74, 0, -19, 69, -50, 30, -23, -21, -78, -73, 2, -56, -82, 2; /M: SY='D'; M= -67, -83, 55, -5, -84, 34, -70, -74, -32, -25, -8, 53, -80, -25, -75, 22, 5, 15, -97, -80; /M: SY='K'; M= -6, -84, 5, 9, -30, 24, -72, -78, 26, 4, -7, 21, -80, -65, 19, 22, 6, -40, -90, -77; /M: SY='P'; M= -3, -89, 41, -4, -85, 20, -5, -79, 3, -48, 56, -35, 57, -17, -25, 2, -70, -34, -91, -27; /M: SY='S'; M= -22, -86, 11, 44, -16, -17, -73, -41, -29, -83, -78, -11, 39, 12, -73, 48, 18, -13, -92, -79; /I: E1=0; IE=-255; DE=-255;» more |
Post-processing [info]
| COMPETES_HIT_WITH | PS50157; PS51801; PS51905; PS51906; PS51907 |
Numerical results [info]
| Total number of hits | 53 in 48 different sequences |
| Number of true positive hits | 53 in 48 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 1 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 98.15 % |
Comments [info]
| Taxonomic range [info] | Eukaryotes |
| Maximum number of repetitions [info] | 2 |
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | CJA_Sigrist |
| Feature key [info] | ZN_FING |
| Feature description [info] | UBZ4-type |
| Version [info] | 3 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
48 sequences
DCR1A_CHICK (Q5QJC4), DCR1A_HUMAN (Q6PJP8), DCR1A_MOUSE (Q9JIC3), FAN1_AILME (D2HNY3), FAN1_CAEBR (A8WZU5), FAN1_CAEEL (P90740), FAN1_DANRE (Q1LWH4), FAN1_HUMAN (Q9Y2M0), FAN1_MOUSE (Q69ZT1), FAN1_ORYSJ (Q5SNL7), POLK_CAEEL (P34409), POLK_HUMAN (Q9UBT6), POLK_MOUSE (Q9QUG2), POLK_SCHPO (O74944), PSO2_SCHPO (Q10264), PSO2_YEAST (P30620), RAD18_ASPFU (Q4WZJ6), RAD18_CANAL (Q5A4N5), RAD18_CANGA (Q6FPI4), RAD18_DEBHA (Q6BLM3), RAD18_EMENI (Q02398), RAD18_EREGS (Q75EN0), RAD18_HUMAN (Q9NS91), RAD18_KLULA (Q6CTZ8), RAD18_MOUSE (Q9QXK2), RAD18_NEUCR (P33288), RAD18_SCHPO (O74747), RAD18_YARLI (Q6CHI1), RAD18_YEAST (P10862), SLX4_HUMAN (Q8IY92), SLX4_MOUSE (Q6P1D7), SPRTN_BOVIN (A5D979), SPRTN_CAEEL (Q22557), SPRTN_DANRE (A0A0G2L7I0), SPRTN_HUMAN (Q9H040), SPRTN_MOUSE (G3X912), SPRTN_RAT (D3ZVU1), SPRTN_XENLA (A0A1L8G2K9), SPRTN_XENTR (F6UH96), UIMC1_HUMAN (Q96RL1), UIMC1_MOUSE (Q5U5Q9), UIMC1_PIG (A0P8Z5), UIMC1_RAT (Q5PQK4), WRIP1_HUMAN (Q96S55), WRIP1_MOUSE (Q91XU0), WRIP1_RAT (Q8CG07), WRIP1_SCHPO (O13984), WRIP1_YEAST (P40151)» more
|
| UniProtKB/Swiss-Prot False negative sequences |
1 sequence
NCAA_ASPFU (Q4WN10) |
| PDB [Detailed view] |
7 PDB
2MRE; 2MRF; 3VHS; 3VHT; 5VF0; 7NV0; 7NV1 |