PROSITE logo
Black ribbon
We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU01263


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU01263
General rule information [?]

Accession PRU01263
Dates 21-FEB-2020 (Created)
19-NOV-2022 (Last updated, Version 4)
Data class Domain;
Predictors PROSITE; PS51915; ZAD
Name Zinc finger-associated domain (ZAD)
Function The ZAD is a protein-protein interaction module with the capability to form homodimers.
Scope(s) Eukaryota
Metazoa
Example(s) Q9VHM6;

Propagated annotation [?]

Keywords [?]

Metal-binding
Zinc
end case
Zinc-finger

Gene Ontology [?]

case <FTGroup:1>
GO:0008270; Molecular function:zinc ion binding

Features [?]

From: PS51915
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="ZAD #"
BINDING 3 3 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"		 C 1
BINDING 6 6 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"		 C 1
BINDING 53 53 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"		 C 1
BINDING 56 56 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"		 C 1

Additional information [?]

Size range 70-90 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]