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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU01279


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU01279
General rule information [?]

Accession PRU01279
Dates 16-JUL-2020 (Created)
14-FEB-2022 (Last updated, Version 6)
Data class Domain;
Predictors PROSITE; PS51931; BMC_CP
Name Bacterial microcompartment (BMC) circularly permuted domain
Function Bacterial microcompartments (BMCs) are large virion-sized protein assemblies comprised of specific enzymes encased within a protein shell. The shells of all BMCs are architecturally similar, being composed of homohexamers of proteins containing a single BMC domain, homotrimer of proteins containing two BMC domains (that resemble the hexamers in size and shape) and pentamers of proteins containing one BMV domain that assemble into an icosahedral shell. Some instances of the BMC shell domain reveal a circular permutation in which a highly similar tertiary structure is built from secondary structure elements occurring in a different order.
Scope(s) Bacteria
Example(s) P0A1D1;

Propagated annotation [?]

Comments [?]

case <AnyFeature:PS51931==1>
SIMILARITYBelongs to the EutS/PduU family.
else case <AnyFeature:PS51931==2>
SIMILARITYBelongs to the EutL/PduB family.
end case

Gene Ontology [?]

GO:0031469; Cellular component:bacterial microcompartment

Features [?]

From: PS51931
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="BMC circularly permuted #"

Additional information [?]

Size range 90-120 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]