ProRule PRU01282

General rule information [?]

Accession PRU01282
Dates 28-JUL-2020 (Created)
-- (Last updated, Version 1)
Data class Domain;
Predictors PROSITE; PS51353; ARSC
Name ArsC family
Function ArsC is an ~150-residue arsenate reductase that uses reduced glutathione (GSH) to convert arsenate to arsenite with a redox active cysteine residue in the active site. The arsC family also comprises the Spx proteins which are GRAM-positive bacterial transcription factors that regulate the transcription of multiple genes in response to disulfide stress.
Scope(s) Bacteria
Example(s) P52147 (ARSC2_ECOLX);

Propagated annotation [?]

Comments [?]

SIMILARITYBelongs to the ArsC family.

Keywords [?]

case <FTTag:disulf>
Disulfide bond
Redox-active center
end case
case <Feature:PS51353:10-13=C-x*-C>

Features [?]

From: PS51353
Key From To Description Tag Condition FTGroup
case <Feature:PS51353:10-13=C-x*-C>
DISULFID 10 13 /note="Redox-active" disulf
else case <Feature:PS51353:10=C>
ACT_SITE 10 10 ArsC
end case

Additional information [?]

Size range 110-135 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined


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UniProtKB rule member sequences [?]