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annotation rule: PRU01282

General rule information [?]

Accession PRU01282
Dates 28-JUL-2020 (Created)
28-JUL-2020 (Last updated, Version 1)
Data class Domain
Predictors PROSITE; PS51353; ARSC
Name ArsC family
Function ArsC is an ~150-residue arsenate reductase that uses reduced glutathione (GSH) to convert arsenate to arsenite with a redox active cysteine residue in the active site. The arsC family also comprises the Spx proteins which are GRAM-positive bacterial transcription factors that regulate the transcription of multiple genes in response to disulfide stress.

Propagated annotation [?]


Comments [?]

Similarity Belongs to the ArsC family.

Keywords [?]

case <FTTag:disulf>
Disulfide bond
Redox-active center
end case


Features [?]

case <Feature:PS51353:10-13=C-x*-C>
From: PS51353
Key     From     To       Description   Tag   Condition   FTGroup
DISULFID     10     13       Redox-active   disulf      
else case <Feature:PS51353:10=C>
ACT_SITE     10     10           ArsC      
end case


Additional information [?]

Size range 110-135 amino acids
Related rules None
Repeats 1
Topology Undefined
Example P52147 (ARSC2_ECOLX)
Scope
Bacteria
Viruses; Fromanvirus
Comments None

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.


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UniProtKB rule member sequences [?]