PROSITE logo

ProRule logo
PRU01284


General rule information [?]

Accession PRU01284
Dates 11-AUG-2020 (Created)
16-FEB-2023 (Last updated, Version 2)
Data class Domain
Predictors PROSITE; PS51935; NLPC_P60
Name NlpC/P60 domain
Function The NlpC/P60 domain consists of ~110-140 residues and is a primitive papain-like peptidase in the CA clan of cysteine peptidase with a Cys/His/His catalytic triad and a conserved catalytic core.

Propagated annotation [?]


Description [?]

case <FTGroup:1>
+ RecName: EC 3.4.-.-;
end case


Comments [?]

Similarity Belongs to the peptidase C40 family.

Gene Ontology [?]

case <FTGroup:1>
GO:0008234; Molecular function: cysteine-type peptidase activity.

Keywords [?]

end case


Features [?]

From: PS51935
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       NlpC/P60 #        
ACT_SITE     31     31       Nucleophile     C   1
ACT_SITE     82     82       Proton acceptor     H   1
ACT_SITE     94     94             [DEHNQ]   1

Additional information [?]

Size range 110-150 amino acids
Related rules None
Repeats 1
Topology Undefined
Example P0AFV7 (MEPS_SHIFL)
Scope
Bacteria
Viruses; Caudoviricetes
Comments None

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.



UniProtKB rule member sequences [?]