ProRule PRU01284

General rule information [?]

Accession PRU01284
Dates 11-AUG-2020 (Created)
16-FEB-2023 (Last updated, Version 2)
Data class Domain;
Predictors PROSITE; PS51935; NLPC_P60
Name NlpC/P60 domain
Function The NlpC/P60 domain consists of ~110-140 residues and is a primitive papain-like peptidase in the CA clan of cysteine peptidase with a Cys/His/His catalytic triad and a conserved catalytic core.
Scope(s) Bacteria
Example(s) P0AFV7 (MEPS_SHIFL);

Propagated annotation [?]

Identifier, protein and gene names [?]

case <FTGroup:1>
Protein name + RecName: EC=3.4.-.-;
end case

Comments [?]

SIMILARITYBelongs to the peptidase C40 family.

Keywords [?]

Gene Ontology [?]

case <FTGroup:1>
GO:0008234; Molecular function:cysteine-type peptidase activity

Features [?]

From: PS51935
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="NlpC/P60 #"
ACT_SITE 31 31 /note="Nucleophile" C 1
ACT_SITE 82 82 /note="Proton acceptor" H 1
ACT_SITE 94 94 [DEHNQ] 1

Additional information [?]

Size range 110-150 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined


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UniProtKB rule member sequences [?]