PRU01284
General rule information
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| Accession | PRU01284 |
| Dates | 11-AUG-2020 (Created) 16-FEB-2023 (Last updated, Version 2) |
| Data class | Domain |
| Predictors | PROSITE; PS51935; NLPC_P60 |
| Name | NlpC/P60 domain |
| Function | The NlpC/P60 domain consists of ~110-140 residues and is a primitive papain-like peptidase in the CA clan of cysteine peptidase with a Cys/His/His catalytic triad and a conserved catalytic core. |
Propagated annotation
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Description
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case <FTGroup:1>
| + RecName: EC 3.4.-.-; |
end case
Comments
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| Similarity | Belongs to the peptidase C40 family. |
Gene Ontology
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case <FTGroup:1>
GO:0008234; Molecular function: cysteine-type peptidase activity.
Keywords
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end case
Features
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| From: PS51935 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | NlpC/P60 # | |||||||||
| ACT_SITE | 31 | 31 | Nucleophile | C | 1 | |||||||
| ACT_SITE | 82 | 82 | Proton acceptor | H | 1 | |||||||
| ACT_SITE | 94 | 94 | [DEHNQ] | 1 | ||||||||
Additional information
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| Size range | 110-150 amino acids |
| Related rules | None |
| Repeats | 1 |
| Topology | Undefined |
| Example | P0AFV7 (MEPS_SHIFL) |
| Scope | Bacteria
Viruses; Caudoviricetes |
| Comments | None |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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-
UniProtKB/Swiss-Prot sets
Bacteria [35] Viruses [3] All [ 38 ]
- Retrieve set of proteins with 3D structure for this domain