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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU01290


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU01290
General rule information [?]

Accession PRU01290
Dates 08-OCT-2020 (Created)
08-OCT-2020 (Last updated, Version 2)
Data class Domain;
Predictors PROSITE; PS51945; BCOV_NSP3E_NAB
Name Betacoronavirus Nsp3e nucleic acid-binding (NAB) domain
Function Nsp3e is unique to Betacoronaviruses and consists of a nucleic acid- binding domain (NAB) and the so-called group 2-specific marker (G2M). The Nsp3e NAB was shown to bind G-rich single-stranded RNA (ssRNA) and to possess double-stranded DNA (dsDNA) unwinding capability.
Scope(s) Viruses
Betacoronavirus
Example(s) P0C6F7;

Propagated annotation [?]

Keywords [?]

RNA-binding

Features [?]

From: PS51945
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="Nucleic acid-binding #"

Additional information [?]

Size range 95-125 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]