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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU01292


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU01292
General rule information [?]

Accession PRU01292
Dates 26-OCT-2020 (Created)
26-OCT-2020 (Last updated, Version 2)
Data class Domain;
Predictors PROSITE; PS51947; NIRAN
Name Nidovirus RdRp-associated nucleotidyl transferase (NiRAN) domain
Function The NiRAN domain has an essential nucleotidylation activity and its potential functions in nidovirus replication may include RNA ligation, protein-primed RNA synthesis, and the guanylly-transferase function that is necessary for mRNA capping.
Scope(s) Viruses
Nidovirales
Example(s) P0C6Y1;

Propagated annotation [?]

Features [?]

From: PS51947
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="NiRAN #"

Additional information [?]

Size range 150-270 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]