ProRule PRU01294

General rule information [?]

Accession PRU01294
Dates 2-DEC-2020 (Created)
-- (Last updated, Version 1)
Data class Domain;
Predictors PROSITE; PS51949; COV_NSP7
Name Coronavirus RNA-dependent RNA polymerase (RdRp) Nsp7 cofactor domain
Function The Nsp12 RNA-dependent RNA polymerase, that includes an RdRp catalytic domain conserved in all RNA viruses, possesses some minimal activity on its own, but the addition of the Nsp7 and Nsp8 cofactors greatly stimulates polymerase activity.
Scope(s) Viruses
Example(s) P0C6Y1 (R1AB_IBVB);

Propagated annotation [?]

Comments [?]

SIMILARITYBelongs to the coronaviruses polyprotein 1ab family.

Features [?]

From: PS51949
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="RdRp Nsp7 cofactor #"

Additional information [?]

Size range 75-95 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined


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UniProtKB rule member sequences [?]