ProRule PRU01296
General rule information
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| PURL | https://purl.expasy.org/prosite/rule/PRU01296 |
| Accession | PRU01296 |
| Dates | 9-DEC-2020 (Created)
-- (Last updated, Version 1) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51951; COV_NSP9_SSRNA_BD |
Name | Coronavirus (CoV) Nsp9 ssRNA-binding domain |
| Function | Nsp9 is able to bind single-stranded (ss)DNA or ssRNA, although binding of ssRNA is expected to be the native function. The CoV Nsp9 ssRNA- binding domain is a seemingly obligate homodimer but CoV Nsp9 ssRNA-binding domains have diverse forms of dimerization that promote their biological function. |
| Scope(s) |
Viruses Orthocoronavirinae |
| Example(s) | P0C6Y1 (R1AB_IBVB); |
Propagated annotation
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Comments
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| SIMILARITY | Belongs to the coronaviruses polyprotein 1ab family. |
Keywords
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Features
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| From: PS51951 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="Nsp9 ssRNA-binding #" | |||||||||
Additional information
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| Size range | 100-120 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Viruses [59] All [ 59 ]
- Retrieve set of proteins with 3D structure for this domain