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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU01296


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU01296
General rule information [?]

Accession PRU01296
Dates 09-DEC-2020 (Created)
09-DEC-2020 (Last updated, Version 2)
Data class Domain;
Predictors PROSITE; PS51951; COV_NSP9_SSRNA_BD
Name Coronavirus (CoV) Nsp9 ssRNA-binding domain
Function Nsp9 is able to bind single-stranded (ss)DNA or ssRNA, although binding of ssRNA is expected to be the native function. The CoV Nsp9 ssRNA- binding domain is a seemingly obligate homodimer but CoV Nsp9 ssRNA-binding domains have diverse forms of dimerization that promote their biological function.
Scope(s) Viruses
Orthocoronavirinae
Example(s) P0C6Y1;

Propagated annotation [?]

Comments [?]

SIMILARITYBelongs to the coronaviruses polyprotein 1ab family.

Keywords [?]

RNA-binding

Features [?]

From: PS51951
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="Nsp9 ssRNA-binding #"

Additional information [?]

Size range 100-120 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]