ProRule PRU01311
General rule information
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| Accession | PRU01311 |
| Dates | 10-MAR-2021 (Created)
30-SEP-2022 (Last updated, Version 3) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51966; COV_VIROPORIN_3A_TM |
Name | Coronavirus (CoV) 3a-like viroporin transmembrane (TM) domain |
| Function | 3a-like accessory proteins are transmembrane proteins of the viroporin family that form ion channels in the host membrane and have been implicated in inducing apoptosis, pathogenicity, and virus release. 3a-like viroporins contain a transmembrane domain (TM) and a cytosolic domain (CD). |
| Scope(s) |
Viruses Orthocoronavirinae |
| Example(s) | Q3I5J4 (AP3A_BCRP3); |
Propagated annotation
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Keywords
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Gene Ontology
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| GO:0016020; Cellular component:membrane |
Features
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| From: PS51966 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="CoV 3a-like viroporin TM #" | |||||||||
Additional information
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| Size range | 85-105 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Viruses [18] All [ 18 ]
- Retrieve set of proteins with 3D structure for this domain