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annotation rule: PRU01311

General rule information [?]

Accession PRU01311
Dates 10-MAR-2021 (Created)
10-MAR-2021 (Last updated, Version 2)
Data class Domain
Predictors PROSITE; PS51966; COV_VIROPORIN_3A_TM
Name Coronavirus (CoV) 3a-like viroporin transmembrane (TM) domain
Function 3a-like accessory proteins are transmembrane proteins of the viroporin family that form ion channels in the host membrane and have been implicated in inducing apoptosis, pathogenicity, and virus release. 3a-like viroporins contain a transmembrane domain (TM) and a cytosolic domain (CD).

Propagated annotation [?]


Gene Ontology [?]

GO:0016021; Cellular component: integral component of membrane.

Keywords [?]


Features [?]

From: PS51966
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       CoV 3a-like viroporin TM #        

Additional information [?]

Size range 85-105 amino acids
Related rules None
Repeats 1
Topology Undefined
Example Q3I5J4 (AP3A_BCRP3)
Scope
Viruses; Orthocoronavirinae
Comments None

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.



UniProtKB rule member sequences [?]